2 Bromo 4 Tert Butyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-bromo-4-(tert-butyl)pyridine

    Specifications

    HS Code

    673352

    Name 2-bromo-4-(tert-butyl)pyridine
    Molecular Formula C9H12BrN
    Molecular Weight 214.102 g/mol
    Appearance Solid (Typical)
    Boiling Point 223 - 224 °C
    Melting Point 44 - 47 °C
    Density 1.283 g/cm³
    Solubility Soluble in organic solvents like dichloromethane
    Flash Point 98 °C
    Purity Typically high - 95%+ in commercial products
    Cas Number 128747-68-6

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    General Information
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    Frequently Asked Questions

    As a leading 2-bromo-4-(tert-butyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-bromo-4- (tert-butyl) pyridine?
    2-% cyanogen-4- (tert-butyl) pyridine is a key intermediate in the field of organic synthesis. Although there is no record of this specific compound in the process involved in Tiangong Kaiwu, it can be inferred according to the chemical process ideas and common applications at that time.
    This pyridine derivative is often the cornerstone of the construction of complex organic molecules in chemical preparation. The specific structure of tert-butyl and cyano gives unique chemical activity and steric resistance. In the ancient chemical process concept, attention was paid to the transformation of substances and the creation of new substances. 2-% cyanogen-4- (tert-butyl) pyridine can be used to prepare dyes with special properties. The color and fastness of extremely heavy dyes in ancient dyes. The special structure of this pyridine derivative may be chemically modified to introduce chromophore groups to obtain bright and long-lasting dyes.
    In addition, it may also have potential uses in the direction of pharmaceutical preparation. Although ancient medicine was mostly derived from natural products, it also explored the synthesis of new pharmaceuticals. 2-% cyanogen-4- (tert-butyl) pyridine may be used as a key intermediate to prepare substances with specific pharmacological activities through a series of reactions. The cyano and tert-butyl groups in its structure may affect the interaction between the drug and the biological target, and then exert therapeutic effects.
    In the flavor formulation surface, this compound has a unique structure or imparts a different odor. Ancient fragrance production pursued a unique aroma, and 2-% cyanogen-4- (tert-butyl) pyridine or properly treated became an ingredient for the formulation of unique fragrances, which were used for incense and incense by dignitaries. In short, although "Tiangong Kaiwu" did not directly mention it, according to its chemical process concept, 2-% cyanogen-4- (tert-butyl) pyridine has potential important uses in dyes, medicine, fragrances and other fields.
    What are the synthesis methods of 2-bromo-4- (tert-butyl) pyridine?
    To prepare 2-hydroxy-4- (formyl) pyridine, there are many methods for synthesis, which are described in detail below.
    First, pyridine is used as the starting material, and halogen atoms are introduced at specific positions in the pyridine ring through halogenation reaction. This step can be achieved under suitable reaction conditions by suitable halogenating reagents, such as liquid bromine and N-bromosuccinimide (NBS). Subsequently, the nucleophilic substitution reaction is used to replace the halogen atoms with suitable reagents containing formyl groups and hydroxyl groups, and then the target product is obtained. In this process, precise control of reaction conditions, such as reaction temperature, reaction time, and reagent dosage, will affect the yield and selectivity of the reaction. < Br >
    Second, it can be started from the corresponding pyridine derivatives. For example, a pyridine derivative with suitable substituents is selected and the target product is obtained through a series of functional group conversion reactions. The substituents on the pyridine derivatives can be modified first, and the desired 2-hydroxy- 4 - (formyl) pyridine structure can be gradually constructed through oxidation, reduction, acylation and other reactions. This approach requires careful design of the reaction route according to the structural characteristics of the starting material to ensure the efficient and smooth progress of each step of the reaction.
    Third, with the help of the reaction strategy of transition metal catalysis. The coupling reaction occurs with the substrate containing the pyridine structure and the reagent containing the formyl group and the hydroxyl group under the action of the transition metal catalyst. Commonly used transition metal catalysts such as palladium and nickel usually have high atomic economy and selectivity. However, the selection of catalysts, the design of ligands, and the optimization of reaction conditions are crucial to achieve the best reaction effect.
    The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, production costs, and the purity and yield of the target product, and carefully select the most suitable synthesis path.
    What are the physical properties of 2-bromo-4- (tert-butyl) pyridine?
    2-% hydroxyl-4- (pyridyl) pentyl, is a kind of thing. It has a number of physical properties and has unique uses in various scenes.
    This substance, viewed at room temperature, is colorless and transparent, like clear water and slightly thick, like the initial condensation of nectar, clear and free of impurities. To touch it, it feels smooth, like silk over the finger, but without the flexibility of silk, slightly fluid, but not as easy to disperse as water.
    Smell it, the breath is elegant, not pungent, nor rich fragrance, but a kind of faint air, just like the occasional clear fen in the mountains and ancient trees, which is not noticeable, but looming, lingering on the nose.
    Its melting point is quite low, just like spring snow meets the warm sun, and it melts when it is slightly warmer. The boiling point is relatively high, and in order to boil it into gas, it needs to be burned for a long time, just like an iron pestle grinding a needle, which takes a lot of effort.
    Furthermore, this thing is soluble in water, just like salt entering a clear spring, and it blends with the water silently, seamlessly integrated and indistinguishable from each other. In organic solvents, it also has a certain solubility, showing a unique affinity, such as when close friends meet and accept each other.
    Looking at its density, it is slightly heavier than water. If it is placed on a scale with the same volume of matter, it sinks at the end of the water, just like the old man is calm, not impatient.
    2-% hydroxyl-4- (pyridyl) pentyl, with its unique physical properties, can be used as a raw material in the field of chemical industry to participate in various delicate synthesis, such as craftsman tools, turning ordinary into magical; in the field of medicine, or as a key agent, helping drugs to play a miraculous effect, like a good medicine in the hands of a good doctor, treating diseases and diseases. Its physical properties are the key to opening the door to many applications.
    What is the market price of 2-bromo-4- (tert-butyl) pyridine?
    Today there are diene and tetrapyridyl alkyne, what is the market price?
    The determination of the price of the husband depends on various factors and cannot be determined. First, the price of the raw materials is based. The preparation of diene and tetrapyridyl alkyne requires specific raw materials. If the raw materials are dilute, the mining is labor-intensive and the price is high, and the price of the finished product is also high; if the raw materials are abundant and easy to obtain, the price may be low.
    Second, the manufacturing process is difficult and easy to tie. If the synthesis method is complicated, requires exquisite techniques, high-priced tools and long-term work, during which manpower and material resources are consumed very much, and the market price is not low; if the production is simple, saving labor and time, the price is expected to drop.
    Third, the supply and demand of the city will influence it. If there is a wide demand for the two in the fields of engineering and academia, but the supply is small, the demand is too much, and the price will rise; on the contrary, if the supply exceeds the demand, the market is full and difficult to sell, and the price will fall.
    Fourth, the new technology also has an impact. If the new technology is produced, the quality can be improved and the consumption can be reduced, and the price may change accordingly.
    Furthermore, political regulations, tax rates, etc., can make prices fluctuate. To sum up, if you want to determine the market prices of diene and tetrapyridyne, you must consider all the factors in detail, and then you can get a more accurate judgment.
    What are the precautions for storing and transporting 2-bromo-4- (tert-butyl) pyridine?
    There are many things that should be paid attention to when it comes to hiding.
    The first thing to say about hiding is that there may be differences between the two, and they must be difficult, transparent, and difficult to deal with. If you are in a tidal place, the second layer is vulnerable to water vapor invasion, and the fourth (butyl) may also be due to its characteristics. In addition, the hidden utensils also need to be appropriate to prevent their leakage and need to be hidden. If an unused utensil is used, the second layer may be released, and the fourth (butyl) may also escape, not only the waves, but also the surrounding area may be contaminated, and there is even more fear of dangerous things.
    When it comes to safety, the first thing is safety. Diethane (butyl) may be dangerous to a certain extent, and it must be used to prevent emergencies. It is advisable to travel on the way to avoid severe shocks and collisions to prevent the container from breaking. In addition, the environment of the container also needs to be controlled, and it should not be exposed to high temperatures or light. High temperatures may cause diethane and tetrabutyl (butyl) reactions, causing changes in their properties, and even the risk of explosion or fire.
    In addition, people who work hard are also affected. The characteristics of diethane and tetrabutyl (butyl) are well known. In this way, it is possible to operate with caution and avoid such problems. In addition, two-and-four (butyl) are generally safe and cannot be ignored.