2 Bromo 3 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-bromo-3-(trifluoromethyl)pyridine

    Specifications

    HS Code

    509416

    Chemical Formula C6H3BrF3N
    Molecular Weight 226.009
    Appearance Colorless to light yellow liquid
    Boiling Point 176 - 178 °C
    Density 1.658 g/cm³
    Flash Point 70 °C
    Solubility Soluble in organic solvents like dichloromethane, ethyl acetate
    Purity Typically high - purity products are 98%+
    Cas Number 102005-33-0

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    General Information
    Where to Buy 2-bromo-3-(trifluoromethyl)pyridine in China?
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    Frequently Asked Questions

    As a leading 2-bromo-3-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-bromo-3- (trifluoromethyl) pyridine?
    2-% arsine-3- (triethylmethyl) pyridine, which has a wide range of uses.
    In the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to its unique chemical structure, it can participate in the construction of many drug molecules. For example, in the preparation of some antibacterial drugs, 2-% arsine-3- (triethylmethyl) pyridine can be cleverly combined with other compounds through specific chemical reactions to derive new structures with antibacterial activity, which contributes to the research and development of antibacterial drugs.
    In the field of materials science, it also has outstanding performance. It can be used to prepare functional materials, and by adjusting its combination with other substances or reaction conditions, it can give materials such as special optical and electrical properties. For example, in the preparation of some organic optoelectronic materials, adding an appropriate amount of this compound can optimize the charge transport performance of the material, improve the photoelectric conversion efficiency, and have potential application value in the fabrication of organic Light Emitting Diodes (OLEDs).
    In the field of catalysis, 2-% arsine-3- (triethylmethyl) pyridine can act as a ligand. After coordinating with metal ions, the formed complexes exhibit unique catalytic activity and selectivity. In some organic synthesis reactions, such as carbon-carbon bond formation reactions, such complex catalysts can effectively reduce the activation energy of the reaction, promote the reaction to be more efficient and gentle, and have high selectivity for specific products, greatly improving the economic benefits and environmental friendliness of the reaction. From this perspective, 2-% arsine-3- (triethyl) pyridine has important uses in medicine, materials, catalysis, and other fields, providing strong support for the development of various fields.
    What are the synthesis methods of 2-bromo-3- (trifluoromethyl) pyridine?
    To prepare 2-hydroxy- 3- (triethyl) pyridine, the synthesis method is as follows:
    First, it can be formed by the condensation reaction of the corresponding aldehyde, ammonia and ketone. Under suitable reaction conditions, aldehyde, ammonia and ketone interact, and after a series of complex chemical changes, the ring structure of pyridine is gradually constructed, and hydroxyl and triethyl groups are introduced at specific positions. This reaction requires precise regulation of reaction temperature, pH and the ratio of reactants to make the reaction proceed smoothly in the expected direction and improve the yield and purity of the product.
    Second, it can also be achieved by chemical modification of existing pyridine derivatives. Select a suitable pyridine precursor and introduce hydroxyl and triethyl groups at specific positions by means such as substitution reactions and oxidation reactions. For example, a suitable triethyl-containing group is first introduced into the pyridine ring through a substitution reaction, and then a hydroxyl group is formed at a specific position by an oxidation method. This process requires precise control of the selectivity of the reaction to avoid unnecessary reactions at other positions in the pyridine ring, so as to ensure the target product.
    Third, the reaction path catalyzed by transition metals can also be considered. The unique properties of transition metal catalysts promote the coupling and cyclization of related reactants to achieve the synthesis of 2-hydroxyl-3- (triethyl) pyridine. This method often has the advantages of mild reaction conditions and high efficiency, but it requires high requirements for the selection of catalysts and the optimization of the reaction system, and requires in-depth investigation to obtain the best reaction effect.
    What are the physical properties of 2-bromo-3- (trifluoromethyl) pyridine?
    2-% ether-3- (triethylmethyl) pentyl is a special substance with several physical properties.
    Looking at its shape, under room temperature and pressure, it is mostly a clear and transparent liquid state. The quality is like clear water, and the visibility is good. It is like an invisible elf hiding in it, only showing people in a transparent state.
    When it comes to smell, it emits a unique fragrance. Although it is not a rich and strong fragrance, it seems to be absent, and it faintly reveals a different smell, just like the ancient poem "Dark Fragrance Floating Moon Dusk". This smell is not public, but it can quietly penetrate into the nose and attract people to explore.
    When it comes to boiling point, the boiling point of this substance is moderate, neither easily volatile flow nor something that requires extremely high temperature to gasify. Under normal heating conditions, it gradually turns into a curling gaseous state, like light smoke rising, following the rules of its own physical properties.
    Its density is slightly lighter than that of water. If it is placed in one place with water, it can be seen that it floats leisurely on the water surface, like a light boat floating on the blue waves, distinct and incompatible with each other.
    Solubility is also one of its characteristics. In organic solvents, such as alcohols, esters, etc., it can be well miscible, just like a bosom friend meeting and blending with each other; however, in water, the solubility is quite low, like two worlds, difficult to blend, showing its own hydrophobic characteristics.
    In addition, the substance also has a certain degree of volatility. In an open environment, over time, the amount will gradually decrease, as if there is a pair of invisible hands that slowly pull it away and integrate it into the surrounding air. These physical properties make 2-% ether-3- (triethylmethyl) pentyl unique in many fields, and also open a door to knowledge for those who explore its mysteries.
    What is the market price of 2-bromo-3- (trifluoromethyl) pyridine?
    Now there is 2-hydroxy- 3 - (triethylmethyl) pyridine, what is the price of its market? This is a question related to business affairs. However, if you want to clarify its price, you need to study all the reasons in detail.
    The supply and demand of this product in the city, if there are many people who need it in the market, and there are few suppliers, the price will increase; on the contrary, if the supply exceeds the demand, the price will be reduced. Furthermore, the difficulty of its production also depends on the price. If the production requires exquisite techniques, precious materials, or difficult processes, the price will be high; if the production is easy, the materials used are often, and the process is simple, the price will be flat.
    And the difference in origin also affects the price. In different places, the price of materials and labor costs are different, and the cost of the product produced is different, and the price is also different. And the competition situation of the market cannot be ignored. If there are many people in this market, they will fight hard to attract customers, or there will be a price reduction; if there are few people in the market, and they are almost unique, the price can be set by them.
    However, according to my current feelings, it is difficult to determine the price of the market without knowing the supply and demand, production, origin, and competition of 2-hydroxy- 3- (triethyl) pyridine. If you want to know the details, you should enter the market for a detailed investigation, consult all merchants, and visit all producers, gather the feelings of all parties, synthesize and break them, and then you can get their near-real price.
    What should be paid attention to when storing and transporting 2-bromo-3- (trifluoromethyl) pyridine?
    When storing and transporting 2-hydroxyl-3- (triethylmethyl) pyridine, many matters need to be carefully noted.
    When storing, the temperature and humidity of the environment should be the first priority. This substance should be placed in a cool and dry place. If the temperature and humidity are too high, it may cause its chemical properties to change. For example, under high temperature, it may cause its decomposition reaction, and when the humidity is high, it may also promote its moisture deterioration, affecting its quality and utility.
    Furthermore, the storage place must be well ventilated. Because it may have a certain volatility, if the ventilation is not smooth, the volatile gas will accumulate, which may affect the surrounding air quality. Second, when it reaches a certain concentration, when it encounters an ignition source such as an open flame, there is a risk of fire or even explosion.
    In the choice of storage containers, it should not be ignored. When using suitable materials to prevent chemical reactions with the substance. Such as some metal containers, or with 2-hydroxyl-3- (triethylmethyl) pyridine react, causing corrosion of the container and contamination of the substance.
    As for transportation, the packaging must be solid and reliable. This is to prevent bumps, collisions, packaging damage, and material leakage during transportation. Once it leaks, it not only wastes materials, but also may cause pollution to the environment and harm the surrounding organisms.
    The condition of the transportation vehicle also needs to be paid attention to. It should be ensured that the vehicle is clean and free of debris to avoid other substances from mixing with it. And the vehicle should have corresponding safety facilities, such as fire extinguishing devices, to prevent accidents.
    The escort personnel also need to be familiar with the characteristics of the substance and emergency treatment methods. If there is an emergency situation on the way, such as leakage, it can be properly disposed of in time to minimize the harm.