2-bromo-3-iodo-5-methoxypyridine

2-Bromo-3-iodine-5-methoxypyridine is a kind of organic compound. Its physical properties have unique properties. At room temperature, it may be in a solid state, its color, or white to light yellow powder shape, due to the structure of the halogen atoms and methoxy groups containing bromine and iodine.
When it comes to melting point, due to the force between molecules, halogen atoms and methoxy groups can enhance the interaction between molecules, resulting in a relatively high melting point. However, the exact melting point value needs to be accurately determined by experiments. Usually halogen-containing organic compounds have a melting point of more than tens of degrees Celsius to 100 degrees Celsius, depending on their specific structure and purity.
In terms of boiling point, due to the influence of halogen atoms and methoxy groups in the molecular structure, its boiling point is not low. Halogen atoms increase the molecular weight and polarity, and methoxy groups affect the intermolecular forces, so that gasification requires more energy. Generally speaking, the boiling point of such polysubstituted pyridine compounds may reach more than 200 degrees Celsius. Due to the complex structure, the exact value still needs to be experimentally determined.
In terms of solubility, it is different from that of organic solvents. Due to a certain polarity, it may have better solubility in polar organic solvents such as ethanol and acetone. The interaction between polar solvents and polar groups of compounds can promote their dissolution. In non-polar solvents such as n-hexane, the solubility is poor because the molecular polarity does not match the non-polar solvent. < Br >
Density is also an important physical property. Due to the presence of heavy atoms of bromine and iodine, the molecular weight increases and the density may be greater than that of water. The relative atomic weight of bromine and iodine atoms is large, which increases the mass per unit volume. The specific density value needs to be measured experimentally.
The physical properties of 2-bromo-3-iodine-5-methoxy pyridine are significantly affected by the substituents in the molecular structure. In the fields of organic synthesis, medicinal chemistry, etc., its physical properties are of great significance to the choice of separation, purification and reaction conditions.

2-Bromo-3-iodine-5-methoxypyridine is one of the organic compounds. Its chemical properties are unique and worth exploring.
First of all, its halogen atom-related properties. The molecule contains two halogen atoms of bromine and iodine, and both bromine and iodine have certain activities. Bromine and iodine atoms can participate in nucleophilic substitution reactions, which is one of its important chemical properties. Due to the electron absorption of halogen atoms, the electron cloud density on the pyridine ring is reduced, and the adjacent and para-carbon atoms are more vulnerable to attack by nucleophilic reagents. In case of suitable nucleophilic reagents, halogen atoms can be replaced to derive a variety of new compounds.
Furthermore, the influence of methoxy groups cannot be ignored. The electron cloud density of the pyridine ring can be increased by methoxy group as the power supply group, especially for its neighbor and para-position. This electron effect interacts with the electron-withdrawing effect of the halogen atom to jointly determine the molecular reactivity and selectivity. For example, in electrophilic substitution reactions, methoxy groups make the reaction easier to occur in its neighbor and para-position, while halogen atoms tend to be in the meta-position. The combined effect of the two results in complex reaction check points.
And because of its pyridine ring, the pyridine ring has a certain alkalinity. The lone pair electrons on the nitrogen atom can bind protons. Although the alkalinity is weaker than that of aliphatic amines, under certain conditions, it can react with acids to form salts. This property is also important in organic synthesis and reaction.
In addition, the solubility of this compound in different solvents is different, which has a great impact on its reaction process and product separation. And its stability is restricted by external factors such as temperature and light. Under high temperature or light, reactions such as halogen atom removal may be triggered, resulting in molecular structure changes.
2-Bromo-3-iodine-5-methoxy pyridine has rich chemical properties. In the field of organic synthesis, after rational design of reactions, it can be used to construct complex organic molecules, providing important intermediates for new drug development, materials science and many other fields.

There are several common methods for the synthesis of 2-bromo-3-iodine-5-methoxypyridine as follows.
One is to use 5-methoxypyridine as the starting material. The bromination reaction of 5-methoxypyridine is first carried out, and a suitable bromination reagent, such as N-bromosuccinimide (NBS), can be selected. Under suitable reaction conditions, such as in an organic solvent, the temperature and reaction time can be controlled, and bromine atoms can be introduced at specific positions in the pyridine ring to obtain 2-bromo-5-methoxypyridine. Subsequently, this product is used as the substrate, and then the iodization reaction is carried out. Using iodine and suitable oxidants, such as hydrogen peroxide, in a suitable reaction system, 2-bromo-3-iodine-5-methoxy pyridine can be obtained.
Second, it can also start from methoxy-containing pyridine derivatives and undergo a halogen atom exchange reaction. Iodine atoms are introduced first, and then bromine atoms are introduced through a halogenation reaction. Specifically, 3-iodine-5-methoxy pyridine is used as the raw material, under suitable catalyst and reaction conditions, reacts with brominating reagents, and is replaced by halogen atoms to obtain the final target product.
Furthermore, a multi-step reaction route can be designed. Using a suitable aromatic compound as the starting material, the pyridine ring is first constructed, and the methoxy group is introduced at the same time, and then the bromination and iodization reactions are carried out in sequence. This process requires fine control of the reaction conditions to ensure the selectivity and yield of each step of the reaction. Each step of the reaction requires consideration of many factors such as the ratio of reactants, reaction temperature, reaction time, and solvent selection in order to synthesize 2-bromo-3-iodine-5-methoxy pyridine efficiently and with high purity.

2-Bromo-3-iodine-5-methoxypyridine, which is used in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate. Due to the properties of halogen atoms and methoxy groups in its structure, chemists can skillfully transform it through multiple reactions such as nucleophilic substitution and coupling to synthesize complex compounds with biological activity. Such as building pyridine derivatives with specific structures, or laying the foundation for the development of new drugs, it makes excellent contributions to the drug development process to overcome difficult diseases.
In the field of materials science, it also has potential. Due to the influence of the conjugated structure and substituents of the pyridine ring, it can participate in the preparation of materials with special photoelectric properties. By chemical modification, it can be integrated into polymer or organic semiconductor material systems, or the conductivity and fluorescence of materials can be improved. In the frontier fields of organic Light Emitting Diode (OLED) and solar cells, it is possible to improve material properties and optimize device efficiency.
In the field of pesticide chemistry, it cannot be ignored. Pyridine compounds often exhibit good biological activity, and 2-bromo-3-iodine-5-methoxypyridine can be structurally modified to create new pesticides. It has the functions of insecticide, sterilization, and weeding, providing new ways for agricultural pest control and crop protection, and contributing to sustainable agricultural development.

The market price of 2-bromo-3-iodine-5-methoxypyridine is difficult to say in a word. Its price often varies due to many reasons, such as the difficulty of preparation, the amount of market demand, and the wide range of production sources.
The difficulty of preparation has a great impact on its price. If the preparation method is difficult, rare reagents are required, or harsh conditions are involved, resulting in a significant increase in cost, its price will also be high. On the contrary, if the preparation is convenient, the cost will decrease, and the price will follow.
The amount of market demand also affects its price. If this product is widely used in medicine, chemical industry and other fields, the demand is strong, but the supply is limited, its price will rise. However, if the demand is sluggish and the supply exceeds the demand, the price will tend to drop.
Wide and narrow production sources are also the key. If there are many manufacturers and fierce competition, the price may decrease in order to compete for market share. On the contrary, if there are few producers and the trend of monopoly is gradually formed, the price will be higher.
Looking at "Tiangong Kaiwu", although there is no market price for this product, its theory of "expensive grains but cheap gold and jade" is also suitable for this. That is to say, the price of something depends on its use and supply and demand. The price of 2-bromo-3-iodine-5-methoxypyridine follows this path, either high or low, and it is not constant. To know its exact market price, you need to check the real-time market conditions of chemical raw materials and consult relevant manufacturers or distributors before you can get it.