2-BROMO-3-(HYDROXYMETHYL)PYRIDINE

2-Bromo-3- (hydroxymethyl) pyridine, this is an organic compound. Looking at its physical properties, under room temperature and pressure, it is mostly solid, white to light yellow crystalline powder, which is caused by the intermolecular force to take on such a form.
Its melting point range is about [X] ° C to [X] ° C. The reason why the melting point is in this range is closely related to the molecular structure. There are bromine atoms and pyridine rings in the molecule, which increase the interaction between molecules and increase the lattice energy, so the melting point is relatively high.
When it comes to solubility, the compound has a certain solubility in organic solvents such as ethanol and dichloromethane. This is because these organic solvents can form interactions such as van der Waals forces and hydrogen bonds between the molecules of the compound, which can help them dissolve. However, their solubility in water is relatively small, the hydrophobic effect of the pyridine ring and the bromine atom, and the limited hydrophilicity of the hydroxymethyl group, together lead to their low degree of solubility in water.
Its density is about [X] g/cm ³, and the density is also determined by the relative mass of the molecule and the way the molecule is stacked. The relative mass of the bromine atoms in the molecule is relatively large, which increases the overall relative mass, which in turn affects the density.
In addition, the compound has a certain degree of volatility, but the volatility is weak. This is due to the existence of various interaction forces between molecules, which limit the ability of molecules to escape from the solid surface.
In conclusion, the physical properties of 2-bromo-3- (hydroxymethyl) pyridine are shaped by its unique molecular structure and play a key role in its application in many fields.

2-Bromo-3- (hydroxymethyl) pyridine is one of the organic compounds. It has a variety of chemical properties, so let me talk about them one by one.
First of all, the bromine atom in this compound is quite active. As a good leaving group, the bromine atom can play a role in many nucleophilic substitution reactions. For example, if there is a nucleophilic agent such as alkoxides and amines, the bromine atom will leave happily, and the nucleophilic reagent will take its place to form a new compound. Such reactions are commonly used in the construction of complex organic molecular structures, and various derivatives can be created by using different nucleophilic reagents.
In addition, the hydroxymethyl group in its molecule also has unique characteristics. Hydroxyl groups are nucleophilic and can participate in esterification reactions. When it meets carboxylic acid or acyl chloride, under appropriate catalytic conditions, the oxygen atom in the hydroxyl group will attack the acyl carbon atom and undergo a series of transformations to form corresponding ester compounds. Such ester products may find a place in the fields of drug synthesis and material preparation.
In addition, the pyridine ring also has a profound impact on the properties of the compound. The pyridine ring has a certain alkalinity, and the lone pair electrons on the nitrogen atom can combine with the acid to form a salt. At the same time, the pyridine ring can participate in various aromatic electrophilic substitution reactions. Although the electron cloud density of the pyridine ring is relatively low compared with that of the benzene ring, the electrophilic substitution activity is slightly inferior, but under suitable conditions and the assistance of the activating group, halogenation, nitrification, sulfonation and other reactions can also occur.
Moreover, the chemical properties of 2-bromo-3- (hydroxymethyl) pyridine make it widely used in the field of organic synthesis. Or as a key intermediate, it can be converted into organic compounds with more complex structures and unique functions through multi-step reactions, and has potential application value in many fields such as medicine, pesticides, and materials science.

The common synthesis methods of 2-bromo-3- (hydroxymethyl) pyridine are important topics in the field of organic synthesis. There are several common methods for its synthesis.
One can be started from pyridine derivatives. Using suitable pyridine compounds as raw materials, through specific chemical conversion steps. For example, halogen atoms are introduced at specific positions in the pyridine ring first, and then hydroxymethyl groups are introduced at the corresponding positions through nucleophilic substitution and other reactions. This process requires precise control of reaction conditions, such as temperature, solvent, and reactant ratio. Too high or too low temperature may affect the reaction process and product purity; the choice of solvent is also critical, and it is necessary to conform to the characteristics of each step of the reaction in order to facilitate the smooth progress of the reaction. < Br >
Second, it can be achieved by the strategy of constructing a pyridine ring. Pyridine rings are constructed by cyclization with raw materials containing bromine and hydroxymethyl groups. This path requires clever design of the raw material structure and reaction process. The control of reaction conditions is extremely important. Cyclization reactions usually require suitable catalysts, and strict requirements for the pH and temperature of the reaction environment.
Third, the method of conversion of functional groups is used. Pyridine derivatives containing other functional groups are first prepared, and then the functional groups are gradually converted into target bromine and hydroxymethyl. This process involves a multi-step reaction, and the reaction selectivity and yield of each step need to be carefully regulated. For example, during functional group transformation, it is necessary to avoid unnecessary side reactions in other parts to ensure the purity and yield of the product.
All these synthesis methods have their own advantages and disadvantages. It is necessary to carefully select the appropriate synthesis path according to actual needs, raw material availability, cost considerations and other factors to efficiently prepare 2-bromo-3- (hydroxymethyl) pyridine.

2-Bromo-3- (hydroxymethyl) pyridine, an organic compound, has important applications in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of a wide variety of drugs. Because its structure contains pyridine rings, bromine atoms, hydroxymethyl groups and other active groups, it can be connected with other molecules through various chemical reactions to form compounds with specific pharmacological activities. For example, it can be modified to develop new drugs targeting specific disease targets, such as anti-tumor drugs, by rationally designing the molecular structure to interact with specific proteins or receptors in tumor cells to exert the effect of inhibiting tumor growth; or developed as antimicrobial drugs, by interfering with the normal physiological and metabolic processes of bacteria through unique chemical structures.
In the field of materials science, 2-bromo-3- (hydroxymethyl) pyridine is also useful. The presence of pyridine rings gives it certain stability and electronic properties, which can be used to prepare functional materials. For example, it can be introduced into polymer systems to improve the electrical, optical or mechanical properties of materials. With the help of chemical synthesis methods, it is polymerized with other monomers to prepare polymer materials with special functions, which can be used to manufacture organic Light Emitting Diodes (OLEDs) to improve luminous efficiency and stability; or to prepare high-performance conductive polymers, which are used in the field of electronic devices.
In the field of organic synthesis chemistry, as an important intermediate, it provides an effective way to construct complex organic molecules. Because it contains multiple activity check points, it can participate in nucleophilic substitution reactions, electrophilic substitution reactions and other reaction types. Chemists can skillfully design reaction routes according to the structural requirements of target molecules, use 2-bromo-3- (hydroxymethyl) pyridine to gradually build a complex molecular framework, and synthesize organic compounds with unique structures and functions, providing a rich material basis and research ideas for the development of organic synthetic chemistry.

Today I have a question about the market price of 2 - BROMO - 3 - (HYDROXYMETHYL) PYRIDINE. This is a product in the field of fine chemicals, and its market price is determined by many factors.
The first to bear the brunt is the cost of raw materials. If the price of the raw materials required to prepare this product fluctuates frequently and widely, the price of 2 - BROMO - 3 - (HYDROXYMETHYL) PYRIDINE will also fluctuate. If raw materials are scarce and the supply is tight, the price will rise; conversely, if the supply of raw materials is sufficient, the price will stabilize or fall.
Furthermore, the simplicity and advanced level of the production process are also key. Complex processes that require high-end technology often require more manpower and material resources, increase costs, and increase product prices. If a new process comes out, it can greatly improve production efficiency, reduce energy consumption, and reduce product costs, and prices will be adjusted accordingly.
The market supply and demand relationship also has a profound impact on prices. If the market has strong demand for this product and limited supply, a seller's market will be formed, and prices will naturally rise; if demand is weak, oversupply, and a buyer's market is formed, prices will be under pressure.
In addition, the brand and reputation of the manufacturer also affect the price. Well-known large factories are famous for their stable quality and comprehensive after-sales service. Their products may be priced slightly higher due to brand premiums.
Looking at the market conditions of the past, the price fluctuations are fickle. Due to the constantly changing factors such as raw materials, processes and market demand, it is difficult to give an exact price. To know the current accurate price, you need to consult the relevant chemical product trading platform, suppliers or industry insiders in detail to obtain it.