2 Bromo 3 Chloro 6 Trifluoromethyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Bromo-3-chloro-6-(trifluoromethyl)pyridine

    Specifications

    HS Code

    979024

    Chemical Formula C6H2BrClF3N
    Molecular Weight 274.44
    Appearance Solid (Typical)
    Boiling Point Data may vary, typically in range relevant to organic halopyridines
    Melting Point Data may vary
    Density Data may vary depending on conditions
    Solubility In Water Low (Typical for such organic halides)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene etc.
    Flash Point Data may vary, relevant to flammability in organic compounds
    Pka Data may vary based on pyridine ring substituents
    Logp Positive value indicating lipophilic nature due to fluoromethyl and halogen substituents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Bromo-3-chloro-6-(trifluoromethyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-Bromo-3-chloro-6- (trifluoromethyl) pyridine?
    2-Bromo-3-chloro-6- (trifluoromethyl) pyridine is also an organic compound. It has a wide range of uses and plays an important role in the fields of medicinal chemistry and pesticide chemistry.
    In medicinal chemistry, it is often a key intermediate for the synthesis of new drugs. Due to its unique chemical structure, other functional groups can be introduced through various chemical reactions to build complex drug molecular structures. Taking the development of antibacterial drugs as an example, researchers hope to obtain new compounds with high antibacterial activity and low toxic and side effects by modifying their structures. The presence of Gaiinpyridine ring and its halogen atom and trifluoromethyl can affect the interaction between the drug and the target, and enhance the affinity and inhibition of the drug against specific bacteria.
    In the field of pesticide chemistry, this compound can be used to create new pesticides. Pyridine compounds often have good biological activities, and the introduction of bromine, chlorine and trifluoromethyl can improve the insecticidal, bactericidal or herbicidal properties of pesticides. If a pesticide is designed and synthesized for specific pests or weeds, its structural characteristics can be used to enable the pesticide to precisely act on the specific physiological process of the target organism, interfere with its normal growth and reproduction, and are environmentally friendly, reducing the impact on non-target organisms.
    In addition, in the fields of materials science, 2-bromo-3-chloro-6- (trifluoromethyl) pyridine may also have potential applications. Because fluorine-containing groups can endow materials with special physical and chemical properties, such as improving the weather resistance and chemical stability of materials, it may be used to develop new functional materials. Although its application or still in the research and exploration stage, the prospect is promising.
    What are the physical properties of 2-Bromo-3-chloro-6- (trifluoromethyl) pyridine
    2-Bromo-3-chloro-6- (trifluoromethyl) pyridine is one of the organic compounds. Its physical properties are quite characteristic, let me tell them one by one.
    Looking at its properties, under normal temperature and pressure, it is mostly in the form of a colorless to pale yellow liquid. This state is also very fluid, like smart water, but it has its own unique quality.
    As for the melting point, after fine determination, it is about a certain low temperature range. This low temperature melting point allows the compound to quietly transform from liquid to solid state in a lower temperature environment, like a sleeping crystal, waiting for external conditions to trigger it to wake up again. The boiling point of
    is also one of the key physical properties. Under certain pressure conditions, its boiling point is within a certain range. When the temperature rises to the boiling point, the compound is like a butterfly breaking the cocoon, sublimating from the liquid state to the gaseous state, opening a new physical state journey.
    In terms of solubility, it shows a certain solubility in common organic solvents, such as ethanol and ether. It can blend with these organic solvents, just like water and emulsion, forming a uniform system. This solubility property provides convenient conditions for its application in many fields such as organic synthesis.
    Density is also a property that cannot be ignored. Compared with water, its density may be different, or greater than or less than water. This difference makes it appear different when mixed with water, either sinking at the bottom or floating on the water surface.
    In addition, the vapor pressure of the compound also has a specific value. At different temperatures, the vapor pressure changes, reflecting the degree of its volatilization. Lower vapor pressure indicates that it is relatively less volatile and can exist more stably at room temperature; conversely, higher vapor pressure means that it is more volatile and needs to be properly stored to prevent dissipation.
    The physical properties of this 2-bromo-3-chloro-6- (trifluoromethyl) pyridine are of great significance in the research of organic chemistry, chemical production and related fields, and have laid a solid foundation for in-depth understanding and rational use of this compound.
    What are the synthesis methods of 2-Bromo-3-chloro-6- (trifluoromethyl) pyridine
    The synthesis method of 2-bromo-3-chloro-6- (trifluoromethyl) pyridine is a very important research content in the field of organic synthesis. Its synthesis path often depends on a variety of organic reaction mechanisms and strategies.
    One of them may be initiated by a compound containing a pyridine structure, and bromine and chlorine atoms can be introduced through a halogenation reaction. In this process, it is necessary to carefully select halogenation reagents and precisely regulate the reaction conditions. If a suitable brominating agent is used, under the action of a suitable temperature, solvent and catalyst, bromine atoms can be introduced into a specific position in the pyridine ring. Next, a suitable chlorination reagent is selected to optimize the reaction parameters again to achieve the localization and introduction of chlorine atoms.
    Second, various strategies can be adopted for the introduction of trifluoromethyl. Trifluoromethyl can be successfully integrated into the pyridine ring by means of nucleophilic substitution or electrophilic substitution reaction with reagents containing trifluoromethyl. This step also requires careful consideration of reagent activity, reaction conditions, and the electronic and spatial effects of existing substituents on the pyridine ring to ensure that trifluoromethyl is accurately integrated into the target location.
    Third, the target compound can also be synthesized by the strategy of constructing a pyridine ring. That is, the key intermediate containing bromine, chlorine and trifluoromethyl is prepared first, and then the pyridine ring is constructed by cyclization reaction. In this path, the synthesis of intermediates and the optimization of cyclization reaction conditions are both crucial.
    When synthesizing 2-bromo-3-chloro-6- (trifluoromethyl) pyridine, the selectivity, yield and control of side reactions of each step of the reaction need to be comprehensively considered. Fine optimization of reaction conditions such as temperature, pressure, solvent, catalyst, etc. can obtain the target product efficiently and with high purity. Each step of the reaction requires precise operation and close monitoring to achieve the desired goal of organic synthesis.
    What are the precautions for storing and transporting 2-Bromo-3-chloro-6- (trifluoromethyl) pyridine?
    2-Bromo-3-chloro-6- (trifluoromethyl) pyridine is an important chemical in organic synthesis. When storing and transporting this chemical, pay attention to many matters.
    The temperature and humidity of the storage environment are the first to bear the brunt. This chemical should be stored in a cool, dry and well-ventilated place. High temperatures may cause changes in its chemical properties, accelerate decomposition or initiate other chemical reactions. High humidity environments may cause it to become damp, which in turn affects its purity and stability.
    Furthermore, it is necessary to pay attention to its compatibility with other substances. 2-Bromo-3-chloro-6- (trifluoromethyl) pyridine should not be stored or transported with strong oxidants, strong bases and other substances. Because it has functional groups such as halogen atoms and trifluoromethyl, it is prone to oxidation reactions when it encounters strong oxidants; when it encounters strong bases, it may trigger reactions such as hydrolysis, which not only destroys the structure of the chemical, but also may pose safety hazards.
    Packaging is also an important point that cannot be ignored. Proper packaging materials must be used to ensure that the packaging is well sealed. Common packaging materials include glass bottles, plastic bottles or metal drums. It is necessary to choose the appropriate one according to the actual situation. If the packaging is not good, chemicals may leak, cause pollution to the environment, and also endanger the safety of personnel.
    During transportation, the relevant transportation regulations must be strictly followed. Transportation vehicles need to be equipped with corresponding emergency treatment equipment to prevent accidents such as leaks and take timely response measures. At the same time, transportation personnel also need to undergo professional training to be familiar with the characteristics and emergency treatment methods of this chemical.
    In short, for the storage and transportation of 2-bromo-3-chloro-6 - (trifluoromethyl) pyridine, all factors such as temperature, humidity, compatibility, packaging and transportation regulations need to be considered to ensure its safety and stability.
    What is the market price of 2-Bromo-3-chloro-6- (trifluoromethyl) pyridine?
    Today there is 2-bromo-3-chloro-6- (trifluoromethyl) pyridine, and its market price is difficult to determine. The price of building a market often changes due to many reasons, which cannot be hidden in a single word.
    According to Guanfu's past "Tiangong Kaiwu", the price of all kinds of materials is related to the distance of origin, the amount of output, and the urgency of need. This 2-bromo-3-chloro-6- (trifluoromethyl) pyridine, if the origin is close and the output is abundant, and the people's needs are not urgent, the price may be cheap. However, the origin is far away, the output is rare, and the user is in urgent need, and the price will be expensive.
    And the rise and fall of the market, and the competition of merchants, also have a great influence on its price. The market is prosperous, and all kinds of industries are prosperous. Those who use this product compete for sale, and the price may rise. If the market is bleak and there are few users, merchants will sell their goods quickly, and the price may drop. And all merchants have different purchase prices, transportation costs, and profits, which also make the price of this product uneven in the market.
    Therefore, in order to know the exact market price of 2-bromo-3-chloro-6- (trifluoromethyl) pyridine, it is necessary to carefully examine the current origin, supply and demand, and market conditions.