2-Bromo-3-Amino-6-Methylpyridine

2-Bromo-3-amino-6-methylpyridine is one of the organic compounds. It has a wide range of uses in the field of medicinal chemistry. It is often a key intermediate in the synthesis of various drugs. Due to its unique chemical structure, it can participate in a variety of chemical reactions and help form complex molecules with biological activity.
In the field of pesticide chemistry, it also has important applications. It can be used through a specific reaction path to produce pesticide products with insecticidal, bactericidal or herbicidal effects. Due to the special properties endowed by its structure, it can precisely act on target organisms and improve the control effect.
In the field of materials science, it has also emerged. It can be used to synthesize materials with special functions, such as optoelectronic materials. Through the chemical reactions it participates in, the material is endowed with unique optical or electrical properties, opening up new avenues for the research and development of new materials.
Furthermore, in organic synthetic chemistry, this compound is an important starting material for the construction of complex pyridine derivatives. Chemists can use clever design of reactions to perform functional group transformation and modification to expand the structural diversity of organic molecules to meet the needs of specific structural compounds in different fields.

There are several common methods for synthesizing 2-bromo-3-amino-6-methylpyridine.
First, 2,6-dimethylpyridine is used as the starting material. First, 2,6-dimethylpyridine is brominated. This step requires the selection of suitable brominating reagents, such as N-bromosuccinimide (NBS). Under appropriate reaction conditions, such as in inert solvents, temperature, light and other conditions are controlled to selectively replace the hydrogen atom on the 2-position methyl to generate 2-bromo-6-methylpyridine. Subsequently, the resulting product is aminylated. Suitable aminylation reagents, such as ammonia gas and catalysts, can be used to promote the amino group to replace the hydrogen atom at the 3-position in the reaction environment of high temperature and high pressure, thereby obtaining 2-bromo-3-amino-6-methylpyridine.
Second, 3-amino-6-methylpyridine can also be used as the starting material. In this case, 3-amino-6-methylpyridine is directly brominated. It is also necessary to carefully select brominating reagents, such as liquid bromine or hydrogen bromide, and consider factors such as reaction solvent, temperature and reaction time, to ensure that bromine atoms accurately replace hydrogen atoms in the 2-position to achieve the synthesis of 2-bromo-3-amino-6-methylpyridine.
Third, it can also be achieved through the gradual functional group transformation of pyridine derivatives. First, the pyridine ring is modified with appropriate substituents to construct a pyridine intermediate containing suitable substituents. Then, through a series of reactions, such as halogenation, amination, etc., bromine atoms and amino groups are gradually introduced, and the position of methyl groups is adjusted. Finally, the target product 2-bromo-3-amino-6-methylpyridine is synthesized. Each step of the reaction requires strict control of the reaction conditions to improve the selectivity and yield of the reaction.

2-Bromo-3-amino-6-methylpyridine is one of the organic compounds. Its physical and chemical properties are of vital significance in the fields of scientific research and chemical industry.
In terms of physical properties, this compound may be solid under normal conditions, but it also varies depending on specific environmental conditions. Its melting point and boiling point are actually key indicators for identifying and separating this compound. It is rare to obtain exact data, but it can be inferred from its molecular structure and similar compounds. Its molecules contain functional groups such as bromine, amino group and methyl group, and the particularity of the structure must affect the melting boiling point. Generally speaking, bromine-containing atoms, due to the relatively large mass of bromine atoms, the intermolecular force is enhanced, or the melting point and boiling point are increased; amino groups can form hydrogen bonds, which will also affect the melting boiling point, making them higher than ordinary hydrocarbon compounds.
In terms of its chemical properties, bromine atoms have high activity and are often the activity check point of nucleophilic substitution reactions. Nucleophilic reagents are prone to attack this bromine atom, causing bromine to be replaced to form new compounds. For example, with nucleophilic reagents such as alcohols and amines, substitution reactions can occur. Amino groups also have important chemical activities, are basic, and can react with acids to form salts. And the carbon atom in the ortho-amino position, due to the electron-giving effect of the amino group, the electron cloud density increases, which is in the electrophilic substitution reaction, or is a preferential attack check point. In addition, although the methyl group is relatively stable, under specific conditions, such as the action of strong oxidants, oxidation reactions may also occur.
The physicochemical properties of 2-bromo-3-amino-6-methylpyridine are determined by their unique molecular structure, and these properties have laid a solid foundation for its application in organic synthesis, drug development and other fields.

Looking at this question, I am inquiring about the market price range of 2-bromo-3-amino-6-methylpyridine. However, the price of the market often varies from time to time, and it is also determined by various factors, such as the price of raw materials, the trend of supply and demand, the complexity of the manufacturing process, and the purity of the product.
In the past, the price of this chemical in the market has not changed. If it is of ordinary quality and does not reach very high purity, the price per gram may be around tens of yuan to hundreds of yuan. If high purity and refined products are required, the price will increase, and it is unknown whether it is per gram or over 100 yuan, or even hundreds of yuan.
Today's market is changing rapidly. If you want to know the exact price, you should check the chemical raw material trading platform carefully, or ask the merchant specializing in this chemical. It must tell you the real price according to the current situation. And the market is different in different places, and the price is also different. If you inquire in person, you can determine the number. Don't just rely on the price of the past to judge today's market.

2-Bromo-3-amino-6-methylpyridine is a key intermediate in organic synthesis and is widely used in many fields such as medicine, pesticides and material science. Its manufacturers are all over the world.
In China, many chemical companies are involved in the production of this product. Some manufacturers in Shandong, for example, are committed to the manufacture of 2-bromo-3-amino-6-methylpyridine with their profound heritage and exquisite craftsmanship in the field of fine chemicals. With their advanced equipment and strict quality control system, their products are of high quality and are not only sold well in China, but also exported overseas.
Furthermore, Jiangsu also has many powerful manufacturers. They focus on technological research and development and innovation, continuously optimize production processes, and improve product quality and production efficiency. Their products are also highly recognized in the market. In addition to meeting domestic demand, they actively expand into the international market.
Overseas, there are also well-known companies in Europe, America and other regions involved in this field. For example, some fine chemical companies in the United States, with their cutting-edge technology and strong R & D capabilities, have made outstanding achievements in the production and application development of 2-bromo-3-amino-6-methylpyridine. Their products are mostly used in high-end pharmaceutical R & D and production, and are known for their high quality and stability.
European chemical companies should not be underestimated, such as some manufacturers in Germany and Switzerland, with rigorous production attitude and excellent chemical technology, occupy a place in the product market. The products they produce have strict Quality Standards and are widely used in the preparation of high-end pesticides and special materials.
In short, there are many manufacturers of 2-bromo-3-amino-6-methylpyridine. Each manufacturer relies on its own advantages and characteristics to supply the market with products of different quality and specifications to meet the needs of all walks of life.