2-(Boc-amino)-5-pyridinemethanol

2-% 28Boc - amino% 29 - 5 - pyridinemethanol, that is, 2 - (tert-butoxycarbonyl amino) - 5 - pyridinemethanol, is widely used. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, the coexistence of pyridine rings with amino groups and methanol groups containing specific protective groups gives it a variety of reactive activities, and it can be reacted through many chemical reactions to build complex organic molecular structures.
For example, in the field of pharmaceutical chemistry, with its chemical activity, it can participate in the synthesis of a variety of drug molecules. By modifying the pyridine ring, or by strategically removing the amino protecting group and subsequent reactions, compounds with specific biological activities can be designed and synthesized, which is expected to become new drugs.
In the field of materials science, 2 - (tert-butoxycarbonyl amino) -5 -pyridyl methanol may participate in the preparation of functional materials. By reacting with other organic or inorganic materials, the material is endowed with unique properties, such as specific optical, electrical or chemical stability.
In academic research, as an important chemical reagent, it provides a key material basis for the study of organic chemical mechanisms and the exploration of new reactions, enabling chemists to gain in-depth insight into the nature of chemical reactions and develop novel synthesis methods and strategies.

To prepare 2 - (Boc - amino) - 5 - pyridyl methanol, the following methods are often followed.
First, 5 - pyridyl methanol is used as the starting material. Shilling 5 - pyridyl methanol and di-tert-butyl dicarbonate (Boc -2 O) in a suitable solvent, such as dichloromethane, and adding an organic base, such as triethylamine, at room temperature or slightly warmed up, the two react. At this time, the tert-butoxycarbonyl of di-tert-butyl dicarbonate is moved to the amino group of 5 - pyridyl methanol, and the target product is obtained. The reason is that the base can pull out the hydrogen of the amino group and make it a nucleophilic body, and then attack the carbonyl carbon of di-tert-butyl dicarbonate, and through a series of changes, form the desired bond.
Second, it can be started from the halide containing the pyridine ring. If there is 5-halogenated pyridine, it is first prepared with magnesium metal to obtain a Grignard reagent, and then added with formaldehyde to obtain a 5-pyridine methanol derivative. Then, as mentioned above, it is reacted with di-tert-butyl dicarbonate to introduce tert-butoxy carbonyl. Among them, the Grignard reagent has high activity and can be added with the carbonyl group of formaldehyde to extend its carbon chain. After subsequent reactions, it can achieve the purpose of preparation.
Third, the derivative of pyridine is used as the base and modified in multiple steps. For example, pyridine is cyclic aminylated first, then hydroxylated, and then tert-butoxycarbonyl is introduced. The transformation can be achieved in sequence by means of various reactions such as nucleophilic substitution and redox. Each step requires careful temperature control and agent selection to make the reaction move in the desired direction.
All methods have advantages and disadvantages. The actual operation should be based on the availability of raw materials, the complexity of the reaction, the yield and the cost.

2 - (Boc-amino) - 5 - pyridyl methanol, this is an organic compound. Its physical properties are quite important and are related to many chemical applications.
First, the appearance is usually white to white solid powder, which is delicate and uniform, like snow falling in the early winter, with a pure texture. This form is convenient for storage and use, and it is easy to accurately weigh in laboratory operations.
Besides, the melting point is about a certain temperature range, which is the critical value for its transformation from solid to liquid. The determination of the melting point is like exploring the secret code of a substance, which is of great significance for identifying its purity. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point decreases and the range becomes wider.
Its solubility is also worthy of attention. In common organic solvents, such as dichloromethane and chloroform, it shows good solubility, just like fish entering water and dispersing freely. However, the solubility in water is poor, just like the incompatibility of oil and water. This difference in solubility plays a key role in the separation and purification steps of organic synthesis, allowing for the selection of suitable solvents to achieve effective separation of target compounds and impurities.
also has density. Although the value is not often mentioned, it silently affects many reaction processes. In mixed systems, the density difference determines the stratification of substances, which facilitates the reaction operation and product separation.
In addition, its stability cannot be ignored. In normal temperature, pressure and dry environment, the properties are relatively stable and can be stored for a long time. However, in case of extreme conditions such as strong acid and alkali, it is like a fragile boat encountering strong winds and waves, and the structure is easily damaged, and chemical reactions occur, resulting in changes in the original properties.
In summary, the physical properties of 2- (Boc-amino) -5-pyridyl methanol, from appearance to melting point, solubility, density and stability, play a decisive role in its application in organic synthesis, drug development and other fields, just like the various components of precision instruments, all of which are indispensable.

2-% 28Boc-amino% 29-5-pyridinemethanol is an important compound in the field of organic chemistry. As for the stability of its chemical properties, its molecular structure and related reaction characteristics need to be carefully investigated.
Looking at its structure, Boc-amino groups have a certain protective effect, which can maintain the relative stability of amino groups under specific reaction conditions and prevent unnecessary chemical reactions. The pyridine ring structure, due to the existence of its conjugate system, endows the molecule with a certain degree of electron delocalization, which in turn affects its chemical activity. The methanol group on the ring has the typical reactivity of hydroxyl groups and can participate in reactions such as esterification and oxidation.
Generally speaking, under extreme conditions such as normal temperature and pressure and isolation of strong acids, strong bases and strong oxidants, the chemical properties of 2-% 28Boc-amino% 29-5-pyridinemethanol can be said to be stable. In case of specific reagents or reaction conditions, such as high temperature and the presence of specific catalysts, either the Boc protecting group or the methanol group may react, resulting in changes in the molecular structure.
For example, under acidic conditions, the Boc protecting group is prone to deprotection reaction, releasing free amino groups. The methanol group can be oxidized to an aldehyde group or even a carboxyl group under appropriate oxidation conditions. Therefore, although it may be stable under normal and mild conditions, in a changeable chemical environment, it is necessary to carefully consider the influence of various factors on its stability in order to obtain the certainty of its chemical stability.

I look at this question, and I am inquiring about the price range of 2 - (Boc-amino) -5 - pyridinemethanol in the market. However, the price of this chemical often changes for many reasons.
First, the quality difference, if it is a high-purity, high-quality product, the price must be higher than that of ordinary purity. Second, the purchase quantity is large, the purchase is large, the merchant may give a discount, the unit price is low; the purchase in small quantities, the unit price is high. Third, the trend of supply and demand, if the market oversupply, the price will decline; if the supply exceeds the demand, the price will rise. Fourth, the sources are different, and the prices of domestic and imported products are also different due to factors such as cost and brand.
According to past market conditions, if this chemical is of ordinary purity and purchased in small quantities, the price per gram may be between tens of yuan and more than 100 yuan; if purchased in large quantities and the purity requirements are not very high, it may be up to tens of yuan per gram. However, if you import high purity, buy in small quantities, or more than 100 yuan per gram, or even higher.
Be aware that the market is unpredictable, and if you want to know the exact price range, you should consult chemical product suppliers and chemical sales platforms to carefully review recent quotations.