2-BENZYLOXY-5-BROMO-6-METHYLPYRIDINE

2-Benzyloxy-5-bromo-6-methylpyridine is also an organic compound. Its physical properties are quite important and are related to many practical applications.
The properties of this compound are often solid at room temperature and pressure, and it may be a white to light yellow crystalline powder. Such appearance characteristics are of great significance in the identification and preliminary determination of its purity. The morphology of the powder affects its fluidity and dispersibility during processing and operation.
Melting point is one of its key physical properties. After determination, the melting point range is about [specific value] ℃. The determination of the melting point can help determine the purity of the compound. The higher the purity, the closer the melting point to the theoretical value, and the narrower the melting range.
The boiling point is also an important indicator. Under specific pressure conditions, the boiling point is about [specific value] ° C. Boiling point information is crucial during distillation, separation, etc., and appropriate temperature and pressure conditions can be selected accordingly to achieve effective separation and purification.
In terms of solubility, 2-benzyloxy-5-bromo-6-methylpyridine behaves differently in organic solvents. In common organic solvents such as ethanol and dichloromethane, it has certain solubility. Moderate heating or stirring can increase its dissolution rate and degree. However, the solubility in water is very small, and this property can be exploited in extraction, phase separation and other operations to achieve separation from water-soluble impurities.
Density is also a physical property that cannot be ignored. Its density is about [specific value] g/cm ³. Density data provide a necessary basis for precise experimental operations in terms of solution preparation, reaction system volume calculation, etc.
In addition, the stability of the compound also belongs to the category of physical properties. Under normal storage conditions, it should be stored in a cool, dry and well-ventilated place. If exposed to high temperature, humidity or strong light, it may cause decomposition or deterioration, causing changes in its physical properties and chemical activities.

2-Benzyloxy-5-bromo-6-methylpyridine is a compound that has attracted much attention in the field of organic synthesis. Its main uses cover the following ends.
First, in the field of medicinal chemistry, it is often used as a key intermediate. Taking the development of new antibacterial drugs as an example, chemists can create molecules with unique antibacterial activities by delicately modifying and transforming their structures. Because of its specific structure composed of pyridine ring, benzyloxy group, bromine atom and methyl group, it can precisely fit with specific targets in bacteria and interfere with the normal physiological process of bacteria, thus achieving antibacterial effect.
Second, in the field of materials science, it also has important uses. Scientists can introduce it into the structure of polymer materials to give the material special optical or electrical properties. For example, synthesize materials with specific fluorescence properties and apply them to optical sensors. The conjugated system and functional groups in this compound structure can regulate the electron cloud distribution of the material and affect its luminescence behavior.
Third, it also plays an important role in the field of pesticide chemistry. It can be rationally designed to develop high-efficiency and low-toxicity pesticides. With its special structure, it can produce biological activity against specific pests or pathogens, or interfere with the nervous system of pests, or inhibit the growth and reproduction of pathogens, and is environmentally friendly, with low residues, contributing to sustainable agricultural development.
Overall, 2-benzyloxy-5-bromo-6-methylpyridine has shown broad application prospects in many fields such as medicine, materials, and pesticides, providing an important material basis for technological innovation and development in various fields.

To prepare 2-benzyloxy-5-bromo-6-methylpyridine, it can be synthesized according to the following ancient method.
The starting material is 5-bromo-6-methylpyridine-2-alcohol and benzyl halide, which can be used in a suitable reaction environment to form the target product. Generally speaking, starting with 5-bromo-6-methylpyridine-2-ol, it is placed in an appropriate amount of organic solvents, such as N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc. Such solvents can dissolve the raw materials well and provide a uniform environment for the reaction.
Subsequently, an appropriate amount of alkali is added, such as potassium carbonate, sodium carbonate, etc. The action of the alkali is to deprotonate the hydroxyl group of 5-bromo-6-methylpyridine-2-ol and enhance its nucleophilicity. The deprotonated alkoxide anion has a strong nucleophilic attack on the benzyl carbon atom of the benzyl halide.
Benzyl halide, benzyl bromide or benzyl chloride are often selected. During the nucleophilic substitution reaction, the halogen atom of the benzyl halide leaves and binds to the alkoxide anion to form 2-benzyloxy-5-bromo-6-methylpyridine.
The reaction temperature is very critical and is usually controlled in the moderate range, about 50-100 ° C. If the temperature is too low, the reaction rate will be slow; if the temperature is too high, it may cause side reactions. During the reaction process, thin-layer chromatography (TLC) can be used to monitor, depending on the disappearance of the raw material point and the formation of the product point, the reaction process can be judged.
After the reaction is completed, the reaction solution is treated by conventional post-treatment. For example, dilute with water first, and then extract with an organic solvent to collect the organic phase. The organic phase is dried with a desiccant such as anhydrous sodium sulfate to remove moisture. After that, the organic solvent is removed by reduced pressure distillation to obtain a crude product.
The crude product is refined by column chromatography or recrystallization, and a suitable eluent or solvent system is selected to obtain a pure 2-benzyloxy-5-bromo-6-methylpyridine. In this way, according to the above steps, the synthesis of this compound can be achieved.

There is a question today, what is the market price of 2-benzyloxy-5-bromo-6-methylpyridine. However, the market price of this chemical is difficult to say in a single word. The price of the cover often changes for many reasons, and the reports from various sources are also different.
First, the situation of supply and demand has a great impact on its price. If there are many people who want it, and the supply is small, the price will necessarily increase; on the contrary, if the supply exceeds the demand, the price may fall. Second, the price of raw materials for this chemical also affects its market value. If the price of raw materials rises, the price of products often rises accordingly; if the price of raw materials falls, the price of products may also decrease. Third, different places have different prices due to transportation costs, taxes, etc. And different production processes and quality can also make prices different.
If you want to know the exact price, you can visit the chemical trading platform, which often lists many suppliers and their quotations, which can be compared. Or consult professional chemical sales merchants, who have been involved in this industry for a long time, have a good understanding of the market, and can tell the approximate price. However, this price is not constant and often changes with the market, so you need to pay attention to it in real time.

2-Benzyloxy-5-bromo-6-methylpyridine is an organic compound. When storing and transporting, care should be taken to ensure safety and maintain its good quality.
At the time of storage, the first environment is dry and cool. This compound is afraid of water, and the humid environment is prone to adverse reactions such as hydrolysis, which damages its structure and purity. The cool temperature can reduce the molecular activity and inhibit its spontaneous reaction. The warehouse temperature should be controlled between 2-8 ° C.
Furthermore, it should be stored in a dark place away from light. Light or promote photochemical reactions and cause deterioration. Choose a brown bottle or opaque container to hold it, tightly sealed to prevent air and moisture from invading.
Storage should also be kept away from fire sources, heat sources and oxidants. Due to its flammability, there is a risk of explosion in case of open flames, hot topics or contact with oxidants. Substances of different chemical properties should be stored separately, and must not be mixed to avoid dangerous reactions.
As for transportation, make sure that the packaging is intact. Choose a sturdy container and fill it with cushioning materials to prevent vibration and collision from causing the packaging to break. Strictly control the temperature during transportation and maintain a cool state. Refrigerated trucks or ice packs can be used.
Transportation personnel also need professional training, familiar with the characteristics of the compound and emergency treatment methods. The means of transportation should be clean and free of other chemicals to prevent cross-contamination. And transport according to the specified route, avoid densely populated areas and busy traffic sections. In this way, Fang to ensure the safety and stability of 2-benzyloxy-5-bromo-6-methyl pyridine during storage and transportation.