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What is the chemical structure of 2- [benzyl (methyl) amino] ethyl methyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
This is an organic compound whose name is 2 - [benzyl (methyl) amino] ethyl, methyl 2,6 - dimethyl - 4 - (3 - nitrophenyl) - 1,4 - dihydropyridine - 3,5 - dicarboxylate. To know its chemical structure, let me tell you in detail.
According to its name, the core of this compound is the structure of 1,4 - dihydropyridine. The pyridine ring is a six-membered nitrogen-containing heterocycle. At the 1,4 position, the hydrogen atom remains and has not been replaced by other groups. In the second position of the pyridine ring, there is a 2 - [benzyl (methyl) amino] ethyl group attached. The benzyl group is benzyl, and the benzene ring is connected to the main structure by methylene; and the nitrogen atom of the benzyl group is still connected to the methyl group. The 3rd and 5th positions of the
pyridine ring are each connected to a carboxylic acid ester group. The carboxylic acid ester connected to the 3rd position is another part of 2- [benzyl (methyl) amino] ethyl; the carboxylic acid ester connected to the 5th position is another part of methyl. The 6th position of the
pyridine ring is connected to a methyl group. The 4th position is connected to a 3-nitrophenyl group, that is, the nitro group is connected to the 3rd position of the benzene ring. < Br >
From this point of view, the compound has a complex structure, and each group is connected to each other to form its unique chemical structure. In this way, the chemical structure of the compound is seen.
What is the main use of 2- [benzyl (methyl) amino] ethyl methyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
2-%5Bbenzyl%28methyl%29amino%5Dethyl methyl 2%2C6-dimethyl-4-%283-nitrophenyl%29-1%2C4-dihydropyridine-3%2C5-dicarboxylate is an organic compound with a wide range of main uses. In the field of medicine, this compound may have the potential to treat cardiovascular diseases. Cardiovascular diseases such as hypertension and coronary heart disease pose a serious threat to human health. The structural properties of the compound may have specific pharmacological effects on the cardiovascular system. For example, it may regulate the tension of vascular smooth muscles, promote vasodilation, and then reduce blood pressure; or affect myocardial contractility and improve the pumping function of the heart.
At the scientific level, this compound can be used as a research material for organic synthesis and medicinal chemistry. Chemists can explore the relationship between structure and activity by modifying and modifying its structure. Through operations such as increasing or decreasing specific groups and changing the positions of substituents, a series of derivatives are synthesized and their biological activities are tested to find compounds with stronger activity and better selectivity, laying the foundation for the development of new drugs.
In the field of materials science, the compound may have potential applications. Its special structure may endow the material with specific optical, electrical and other properties. For example, it may be used to prepare materials with specific photochromic or electrochromic properties, which can be used in smart windows, display devices and other fields to achieve effective regulation of light and current.
In short, 2-%5Bbenzyl%28methyl%29amino%5Dethyl methyl 2%2C6-dimethyl-4-%283-nitrophenyl%29-1%2C4-dihydropyridine-3%2C5-dicarboxylate has important potential uses in the fields of medicine, scientific research and materials science, and opens up new directions for many research and applications.
2- [benzyl (methyl) amino] ethyl methyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate What are the synthesis methods?
To prepare 2 - [benzyl (methyl) amino] ethyl, methyl 2,6 - dimethyl - 4 - (3 - nitrophenyl) - 1,4 - dihydropyridine - 3,5 - dicarboxylic acid esters, there are many methods.
First, the corresponding pyridine derivatives can be used. First, take 2,6 - dimethyl - 4 - (3 - nitrophenyl) - 1,4 - dihydropyridine - 3,5 - dicarboxylic acid as the substrate, and carry out esterification reaction with appropriate alcohols under acid catalysis to obtain the corresponding dicarboxylic acid esters. Subsequently, the dicarboxylic acid ester is reacted with 2 - [benzyl (methyl) amino] ethanol under alkali catalysis, and the alcohol hydroxyl group and ester group are substituted through the nucleophilic substitution process, and then the target product is obtained. In this process, acid catalysts such as p-toluenesulfonic acid and alkali catalysts such as potassium carbonate can be selected. The reaction temperature and reaction time need to be controlled to ensure that the reaction is sufficient and there are few side reactions.
Second, 3-nitrobenzaldehyde, methyl acetoacetate and 2 - [benzyl (methyl) amino] ethanol are used as starting materials. First, 3-nitrobenzaldehyde and methyl acetoacetate were catalyzed by ammonia or amine to construct a dihydropyridine ring through Hantzsch reaction to generate 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate intermediates. After that, the intermediate was reacted with 2 - [benzyl (methyl) amino] ethanol under suitable conditions to achieve the synthesis of the target product. The key to this path lies in the control of the reaction conditions of Hantzsch, and factors such as temperature and catalyst dosage have a great influence on the reaction yield and selectivity.
Third, a step-by-step construction strategy is adopted. The precursor of 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylic acid was synthesized first, and the methyl ester group was introduced after modification. Then, through selective amination reaction, the 2 - [benzyl (methyl) amino] ethyl group was partially connected to obtain the target compound. This method requires fine design of the reaction steps to ensure the smooth progress of each step of the reaction and the purity of the product.
All these methods have their own advantages and disadvantages. The optimal synthesis method should be selected according to the actual situation, such as the availability of raw materials, cost, yield and purity requirements.
What is the market outlook for 2- [benzyl (methyl) amino] ethyl methyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
There is now a product named 2 - [benzyl (methyl) amino] ethyl, methyl 2,6 - dimethyl - 4 - (3 - nitrophenyl) - 1,4 - dihydropyridine - 3,5 - dicarboxylate. The prospect of this product in the market is quite interesting.
In the field of Guanfu medicine, this compound may have unique pharmacological activities. Because its structure contains a core of dihydropyridine, such structures are often found in cardiovascular drugs, which can regulate calcium channels or be beneficial to the prevention and treatment of cardiovascular diseases. Therefore, in the market of cardiovascular drug research and development, there may be opportunities to emerge. If pharmaceutical companies can do good research, in-depth study of its mechanism of action, develop targeted drugs, or open up new market shares.
Furthermore, in the field of organic synthesis, its complex structure can provide challenges and opportunities for synthetic chemists. Synthesis of this compound requires exquisite route design and superb synthesis skills. If the synthesis method can be successfully optimized, the yield and purity can be improved, not only can it meet the needs of its own research and production, but also can be sold to other parties to obtain profits in the chemical raw material supply market.
However, its market prospects are not smooth. The high cost of research and development and the rigor of clinical trials are all obstacles to progress. And the market competition is fierce, and there are many similar or potential replacement compounds. In order to stand out in this market, it is necessary to invest a lot of manpower, material resources and time, and achieve long-term stability in order to gain a place in the market and reap considerable benefits.
2- [benzyl (methyl) amino] ethyl methyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate What are the relevant safety precautions?
2-% 5B benzyl (methyl) amino% 5D ethyl, methyl 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate, this is a chemical substance and should be treated with caution due to its safety precautions.
This substance may have specific chemical activity and latent risk. During operation, the first protection. Be sure to wear appropriate protective equipment, such as lab clothes, gloves and goggles, to prevent contact with skin, eyes and clothing. Due to its possible irritation, if it comes into contact with the skin inadvertently, it should be rinsed with plenty of water immediately and seek medical assistance according to the specific situation; if it enters the eyes, it should be rinsed with plenty of water quickly and seek medical attention as soon as possible.
In addition, the use environment should also be paid attention to. It should be operated in a well-ventilated place to prevent the accumulation of harmful gases. If in the laboratory, it is necessary to use equipment such as fume hoods to ensure air circulation.
Storage is also critical. It should be stored in a dry, cool place away from fire and oxidants. Improper storage or deterioration can even cause dangerous reactions.
In addition, its chemical properties should also be well known. Know its stability, reaction characteristics with other substances, etc., in order to avoid risks during operation and storage. Before mixing other substances, be sure to know whether the two will react dangerously.
In short, when dealing with this chemical substance, we must maintain a rigorous attitude and follow safety procedures to ensure personal safety and the environment.