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2-benzyl-hexahydro-2H-pyrrolo chemical structure of [3,4-c] pyridine-1,3-dione
The chemical structure of 2-benzyl-hexahydro-2H-pyrrolido [3,4-c] pyridine-1,3-dione is described in the classical Chinese genre of Tiangong Kaiwu as follows:
The structure of this compound is formed by a unique structure. Its core is the ring system of pyrrolido [3,4-c] pyridine, which has undergone the state of hexahydro, just like six changes to obtain this shape. The pyridine part of the ring is cleverly connected by nitrogen atoms and carbon atoms to form a stable ring structure, which is like the beams and pillars of ancient exquisite buildings, supporting the whole frame. < Br >
In the second position of the ring system, a benzyl group is connected. The benzyl group, with the benzene ring as the head and the methylene group as the neck, is attached to the main ring. The benzene ring is like a canopy, an aromatic ring composed of six carbon atoms, which emits a unique chemical charm. Its structure is stable, like a solid city. The methylene group is like a bridge, closely connecting the canopy to the main ring.
In addition, the first and third positions of the ring system are each connected to a carbonyl group. The carbonyl group is composed of carbon-oxygen double bonds, which are like pearls inlaid on the ring, giving this compound unique chemical activity. The electronegativity of its oxygen atom makes the carbonyl group an active check point for chemical reactions, which is like a battlefield of war, affecting the chemical properties and reaction direction of the entire compound.
In this way, the chemical structure of 2-benzyl-hexahydro-2H-pyrrolido [3,4-c] pyridine-1,3-dione, through the combination of this ring system, benzyl and carbonyl, forms a complex and delicate chemical entity, showing the wonder of organic chemical structure.
What are the physical properties of 2-benzyl-hexahydro-2H-pyrrolo [3,4-c] pyridine-1,3-dione
2-Benzyl-hexahydro-2H-pyrrolido [3,4-c] pyridine-1,3-dione, which has many physical properties. Its appearance is often white to pale yellow crystalline powder, just like the condensation of fine snow, delicate and pure, shimmering slightly in the sun.
When it comes to the melting point, it is about 160-165 ° C. When the temperature gradually rises, the substance is like spring ice, slowly melting into a liquid state, completing the transformation from solid to liquid. Its solubility is unique. In organic solvents such as ethanol and chloroform, it can dissolve well like fish entering water to form a uniform and transparent solution; however, in water, it seems like oil floating in water, and the solubility is very small.
Furthermore, its density is about 1.25-1.35 g/cm ³. When held in the hand, you can feel that its texture is relatively tight and heavy. This material has good stability. It can be stored for a long time at room temperature and pressure without easy deterioration, just like a stable old man, and it remains the same after time. However, it should be noted that strong light and hot topics should be avoided to prevent its properties from quietly changing and affecting subsequent use.
What is the main use of 2-benzyl-hexahydro-2H-pyrrolo [3,4-c] pyridine-1,3-dione?
2-Benzyl-hexahydro-2H-pyrrolido [3,4-c] pyridine-1,3-dione is one of the organic compounds. It has a wide range of uses and is often a key intermediate in drug synthesis in the field of medicinal chemistry. Due to its special chemical structure, it has the potential to interact with specific targets in organisms, so physicians often use this structure to develop new drugs, such as therapeutic drugs for specific diseases, or lead compounds with specific physiological activities, and then benefit human health and well-being.
In the field of materials science, this compound may also have unique applications. Its structural properties may enable it to participate in the synthesis and modification process of materials, endowing materials with special physical and chemical properties, such as improving the stability, optical properties or electrical properties of materials, etc., to meet the special needs of different fields for material properties and contribute to the progress and development of materials science.
In addition, in the experimental investigation of organic synthetic chemistry, 2-benzyl-hexahydro-2H-pyrrolido [3,4-c] pyridine-1,3-dione is often used as a reactant or intermediate. Chemists use various chemical reactions to explore novel synthesis paths and methods, expand the synthesis of organic compounds, and promote the continuous evolution of organic synthetic chemistry.
What are the synthesis methods 2-benzyl-hexahydro-2H-pyrrolo [3,4-c] pyridine-1,3-dione
The synthesis method of 2-benzyl-hexahydro-2H-pyrrolido [3,4-c] pyridine-1,3-dione is an important topic in the field of organic synthesis. There are several common synthesis paths.
First, the pyridine ring can be initiated by a specific pyridine derivative. First, the pyridine ring is reacted with the benzylation reagent under suitable conditions to introduce the benzyl group. This process requires careful selection of the reaction solvent and catalyst. For example, the use of anhydrous ethyl ether as the solvent and aluminum trichloride as the catalyst can promote the smooth connection of the benzyl group to the specific position of the pyridine ring. Subsequently, the pyridine ring is hydrogenated to achieve the construction of the hexahydro-pyridine structure. Metal catalysts, such as palladium carbon, are commonly used for hydrogenation reactions in hydrogen atmosphere, which can effectively achieve the hydrogenation of pyridine rings. Finally, by means of acylation reaction, a carbonyl group is introduced to form a diketone structure. Suitable acid anhydride or acid chloride can be selected to achieve this conversion under the catalysis of bases, such as pyridine or triethylamine.
Second, pyrrole derivatives can also be started. First, the pyrrole ring is modified, and the structural unit containing benzyl is constructed through a multi-step reaction. Benzyl can be introduced into the pyrrole ring through a nucleophilic substitution reaction. After that, through a cyclization reaction, the pyridine ring is constructed, and the diketone structure is formed synchronously. This cyclization reaction may require specific catalysts and reaction conditions, such as high temperature, Lewis acid catalysis, etc., to promote intramolecular cyclization and condensation.
Furthermore, a series reaction strategy can also be used. A series of successive reaction steps are designed to directly achieve the synthesis of the target molecule in the same reaction system without the separation of intermediate products. This method can simplify the operation process and improve the reaction efficiency. However, the reaction conditions need to be precisely regulated to ensure that each step of the reaction is carried out in an orderly manner. For example, by selecting a suitable substrate and catalyst, the starting material can be directly converted into 2-benzyl-hexahydro-2H-pyrrole [3,4-c] pyridine-1,3-dione through a multi-step continuous reaction.
What is the price of 2-benzyl-hexahydro-2H-pyrrolo [3,4-c] pyridine-1,3-dione in the market?
I haven't heard the price of "2-benzyl-hexahydro-2H-pyrrolo [3,4-c] pyridine-1,3-dione" in the market. This is a fine chemical, and its price is determined for many reasons.
First, it is difficult to prepare. If the synthesis method is complicated, it requires multiple steps of reaction, rare raw materials and special reagents, or strict reaction conditions, such as precise temperature, pressure, pH, and low yield, the cost will be high, and the price will be high.
Second, the price of raw materials. If the raw materials required for synthesis are rare, or the price rises due to changes in market supply and demand, the price of the product will increase. If the origin of the raw materials is damaged, or the international situation causes trade restrictions, the supply of raw materials is less and the demand is more, and the price will rise.
Furthermore, market demand. If this product is widely demanded in the fields of medicine, materials, etc., and merchants see business opportunities, or raise prices due to shortage of supply. On the contrary, if the demand is weak, it will be sold for promotion, and the price may drop.
In addition, the purity is high. High purity is particularly critical in some high-end application scenarios, such as pharmaceutical research and development, electronic material preparation, etc. The preparation is difficult, the cost is high, and the price is higher than that of low purity.
In addition, the scale of production also has an impact. Large-scale production, due to the scale effect, the unit cost may be reduced or the price may be low; small-scale production, the cost sharing is high, and the price is easy to be high.
To know the exact price, consult chemical raw material suppliers, chemical trading platforms, or related industry personnel to obtain real-time and accurate price information.