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What are the main uses of 2-aminopyridine-4-carbonitrile?
2-Aminopyridine-4-formonitrile is an important compound in organic chemistry. It has a wide range of uses in the field of medicinal chemistry and is often a key intermediate in the synthesis of many biologically active drugs. The special structure of the geinpyridine ring and the amino and cyano groups endows the compound with unique chemical properties and biological activities, and can be modified by various chemical reactions to meet the needs of specific drug targets.
In the field of materials science, 2-aminopyridine-4-formonitrile also shows unique value. It can participate in the preparation of functional materials, such as in the synthesis of some optoelectronic materials, by virtue of its structural properties, it can have a positive impact on the optoelectronic properties of materials, such as adjusting the material energy level structure, thereby improving its luminous efficiency or charge transport ability.
Furthermore, in the field of organic synthetic chemistry, it is an important starting material for the construction of more complex organic molecules. With the reactivity of cyano and amino groups, various reactions such as nucleophilic substitution and addition can be carried out to realize the construction of carbon-carbon bonds and carbon-heteroatom bonds, providing an effective way for the synthesis of complex organic frameworks, and assisting organic synthetic chemists in the creation of diverse organic compounds. In conclusion, 2-aminopyridine-4-formonitrile plays an indispensable role in many scientific fields due to its unique structure and reactivity.
What are the physical properties of 2-aminopyridine-4-carbonitrile?
2-Aminopyridine-4-formonitrile is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
First of all, its appearance, under normal temperature and pressure, 2-aminopyridine-4-formonitrile is often white to light yellow solid powder. This color state is easy to intuitively distinguish, and the powder morphology is conducive to its uniform dispersion in the reaction system and improves the reaction efficiency.
The melting point is between 148-152 ° C. The melting point is the inherent property of the substance. At this temperature, the solid 2-aminopyridine-4-formonitrile begins to melt into a liquid state. The determination of the melting point is crucial for the identification and purification of this compound. It can be accurately measured by a melting point tester, and its purity can be judged according to the compatibility of its melting point with the theoretical value.
As for solubility, 2-aminopyridine-4-formonitrile is slightly soluble in water. Because water is a polar solvent, and the polarity of the molecular structure of the compound is limited, it is "similarly soluble", so it is difficult to dissolve in water. However, it is soluble in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). In organic synthesis, these organic solvents are often selected according to the reaction requirements to fully dissolve 2-aminopyridine-4-formonitrile and create a suitable reaction environment to facilitate the smooth progress of the reaction.
Its density is also one of the physical properties. Although the exact value varies depending on the measurement conditions, it is roughly within a certain range. The consideration of density is significant in the steps of material measurement, reaction system ratio, separation and purification, which can help chemists accurately control the reaction process and ensure the accuracy and repeatability of experimental results. The physical properties of 2-aminopyridine-4-formonitrile, such as appearance, melting point, solubility, and density, are essential in chemical research, organic synthesis, and related industrial applications. Chemists need to gain a detailed understanding in order to make good use of this compound and achieve the desired chemical goals.
What is 2-aminopyridine-4-carbonitrile chemical synthesis method?
The chemical synthesis method of 2-aminopyridine-4-formonitrile, although the ancient book "Tiangong Kaiwu" does not directly describe this substance, it can be compared by analogy with the ancient chemical process idea.
In the past, the synthesis of organic nitrile compounds was often obtained by multi-step reaction of nitrogen-containing and cyanyl-containing raw materials. In modern chemical synthesis, 2-aminopyridine can be used as the starting material, and a cyanide group can be introduced by means of a suitable cyanide reagent. One method may first cause the substitution reaction of 2-aminopyridine with haloalkanes to obtain the corresponding substituted pyridine derivatives. Then, under appropriate reaction conditions, such as heating in an organic solvent, adding a catalyst, etc., the halogen atom is replaced by a cyanyl group to obtain 2-aminopyridine-4-formonitrile.
Or from pyridine-4-formonitrile, obtained by amination reaction. Suitable aminizing reagents, such as ammonia and corresponding catalysts, can be used to react under certain temperature and pressure conditions. During the reaction, attention should be paid to the control of the reaction conditions to ensure the selectivity and yield of the reaction. < Br >
Or through other multi-step synthesis paths, the pyridine ring structure is first constructed, and then the amino group and cyano group are gradually introduced. In this process, the reaction steps need to be carefully planned, the feasibility of each step and the influence of side reactions are considered. In this way, the effective synthesis of 2-aminopyridine-4-formonitrile may be achieved.
What is the price range of 2-aminopyridine-4-carbonitrile in the market?
In today's world, it is not easy to know the price range of 2-aminopyridine-4-carbonitrile in the market. The price of this compound often changes for many reasons, and it is difficult to determine a certain number.
First, the purity of this compound has a great impact on its price. If the purity is extremely high, it is almost flawless, and if it is refined by a fine process with very few impurities, its price will be high. However, if the purity is slightly inferior, contains some impurities, and meets the general purpose, its price may be slightly lower.
Second, the market supply and demand trend also affects its price. If many manufacturers compete for this product and demand exceeds supply, the price will rise; conversely, if the supply exceeds demand, the market will be saturated, and the price will fall.
Third, the cost of producing this compound is also the key. The price of raw materials, the simplicity of the production process, and the consumption of manpower and material resources are all related to costs. If raw materials are scarce and difficult to find, or the production process is complicated, high-end equipment and professionals are required, and the cost will be high, and the price will follow.
Due to the rapidly changing market conditions, prices vary from place to place, and it is difficult to determine the exact price range. Or in some prosperous commercial ports, due to the concentration of resources and frequent transactions, the price may be moderate; while in remote places, due to the increase in transportation costs, the price may be slightly higher. < Br >
Although it is difficult to determine the price range, it can be asserted that to know its price, one should consult various chemical raw material suppliers or consult the latest information on chemical product trading platforms to obtain a more accurate price range.
What are 2-aminopyridine-4-carbonitrile storage conditions?
2-Aminopyridine-4-formonitrile is also a chemical substance. Its storage conditions are crucial, related to its stability and quality.
This substance should be stored in a cool and dry place. In a cool place, the temperature should not be too high. If it is too high, it may cause chemical changes and cause changes in its properties. In dry places, avoid moisture intrusion, and its purity will be damaged due to moisture or reactions such as hydrolysis.
and must be placed in a well-ventilated place. Good ventilation can prevent the accumulation of harmful gases, keep the storage environment safe, and prevent the substance from deteriorating due to abnormal local gas concentrations.
In addition, it should be stored separately from oxidants, acids, bases and other substances. This is because 2-aminopyridine-4-formonitrile is chemically active, coexists with various substances, or reacts violently, such as redox, acid-base neutralization, etc., causing the failure of the substance, and even the risk of health safety, such as fire, explosion, etc.
In the choice of storage containers, it should not be ignored. A well-sealed container must be used to prevent the substance from evaporating and leaking, to ensure its quality, and to avoid pollution to the environment. And the container material should be compatible with the substance and not chemically react with it to ensure its stability.
In conclusion, following these storage conditions, 2-aminopyridine-4-formonitrile must be properly preserved to maintain its constant performance and quality.