2-Aminopyridine-3-methanol (2-Aminopyridin-3-yl)methanol

2 + -Aminopyridine-3-methanol ((2-aminopyridine-3-yl) methanol) has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize drugs with special biological activities. For example, when developing targeted therapeutic drugs for specific diseases, with its unique chemical structure, it can precisely combine with disease-related targets to exert therapeutic effects. In the field of pesticides, it can be used to create new pesticides. Because it has certain biological activities, it exhibits inhibitory or killing effects on specific pests or pathogens, which helps to develop efficient, low-toxicity and environmentally friendly pesticide products to ensure the healthy growth of crops. In the field of materials science, it can participate in the synthesis of functional materials. For example, polymerization with other monomers can prepare polymer materials with special optical, electrical or mechanical properties, which are used in electronic devices, optical instruments and other fields. At the same time, in organic synthetic chemistry, as an important organic synthetic block, it can build complex and diverse organic compounds through various chemical reactions, providing an important material basis for the development of organic synthetic chemistry.

2 + -Aminopyridine-3-methanol ((2-aminopyridine-3-yl) methanol) is an organic compound with specific physical properties.
Looking at its properties, it is mostly white to light yellow crystalline powder at room temperature and pressure. This form is easy to store and process, and the surface area of the powdered substance is large, which is conducive to improving the reaction rate in some chemical reactions.
When it comes to the melting point, it is about 120-124 ° C. The melting point is the transition temperature from solid to liquid state of a substance. This value is its characteristic physical constant and can be used to identify and judge the purity. The melting point is fixed and consistent with the literature value, indicating that the purity is high; if the melting point range is wide or deviates from the literature value, it may contain impurities.
Its solubility also has characteristics. It is slightly soluble in water, but it can be better dissolved in organic solvents such as ethanol and dichloromethane. This characteristic is due to its molecular structure. The amino group and pyridine ring in the molecule have certain lipophilicity, while the methanol group has certain hydrophilicity, but the overall lipophilicity is dominant, resulting in good solubility in organic solvents. This solubility is of great significance in organic synthesis, and suitable solvents can be selected for reaction, separation and purification.
In addition, the compound has certain stability, but under extreme conditions such as strong acid, strong base or high temperature, the molecular structure may change, triggering chemical reactions. When storing, it should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to ensure the stability of its physical properties and facilitate subsequent use.

2 + -Aminopyridine-3-methanol ((2-aminopyridine-3-yl) methanol) is an organic compound with a wide range of uses in the field of organic synthesis. Its chemical properties are unique, containing amino and methanol groups, resulting in a variety of reactivity.
First, the amino group is alkaline and can react with acids to form corresponding salts. For example, when it meets hydrochloric acid, it can form a hydrochloride salt. And amino groups are easy to participate in nucleophilic substitution reactions. In many organic synthesis steps, they can attack electrophilic reagents and realize the construction of carbon-nitrogen bonds.
Looking at the methanol group, the hydroxyl group has active hydrogen and can undergo substitution reactions. Like reacting with halogenated hydrocarbons to form ether compounds. At the same time, under oxidation conditions, the hydroxyl group can be oxidized, and the aldehyde group is formed in the primary stage. If further oxidized, it becomes a carboxyl group.
In addition, the pyridine ring of the compound also has special properties. The nitrogen atom on the pyridine ring makes the density distribution of the ring electron cloud uneven, which in turn affects the reactivity of the substituent on the ring. In the electrophilic substitution reaction, the substituent mainly enters the β position (relative to the nitrogen atom) of the pyridine ring, because the electron cloud density at this position is relatively high, which is conducive to the attack of electrophilic reagents. The chemical properties of 2-aminopyridine-3-methanol make it an important intermediate in many fields such as medicine, pesticides, and materials science, and are of great significance for the synthesis of many complex organic compounds.

The synthesis method of 2 + -aminopyridine-3-methanol ((2-aminopyridine-3-yl) methanol) is of interest in the field of chemical synthesis. The synthesis method used to rely on various chemical conversion steps in the past.
One method often uses an appropriate pyridine derivative as the starting material. Or a pyridine with a suitable substituent is selected, and the substituent is converted into an amino group and a methanol group through a specific reaction. For example, a halogen atom, such as chlorine or bromine, can be introduced before a specific position of the pyridine ring. This halogenated pyridine compound reacts with ammonia under suitable conditions, and the halogen atom can be replaced by an amino group to form an amino-containing pyridine derivative. Thereafter, by the reaction of a suitable nucleophilic reagent with another halogen atom on the halogenated pyridine, a group containing methanol group is introduced, and the methanol group is converted into the methanol group through a series of reactions, so as to obtain the target product 2 + -aminopyridine-3 -methanol.
There are also other compounds as starting materials. If the carboxylic acid ester containing the pyridine ring is used as the starting point, the ester group is first converted into methanol group by reduction reaction, and the pyridine ring is modified at the same time, and the amino group is introduced by reaction such as aminolysis, it can also be obtained.
During the synthesis process, various reaction conditions are extremely critical. Temperature, reaction time, proportion of reactants and the catalyst used all have a significant impact on the reaction yield and selectivity. If the temperature is too high or too low, both side reactions may increase or the reaction rate may be too slow. A suitable catalyst can effectively promote the reaction and improve the yield of the target product. And the choice of reaction solvent cannot be ignored. Different solvents have different effects on the solubility and reactivity of the reactants. It is necessary to choose the appropriate solvent according to the specific reaction.

I look at your question, and I am inquiring about the price range of 2-aminopyridine-3-methanol ((2-aminopyridine-3-yl) methanol) in the market. However, the price of this chemical often changes for many reasons, and it is difficult to determine the exact number.
First, its purity has a great impact on the price. If the purity is extremely high, nearly 99% or more, it is suitable for high-end scientific research, pharmaceuticals and other fine-edge fields, and its price is high; if the purity is slightly lower, it is only used for general industrial use, and the price is relatively low.
Second, the purchase quantity is also key. A small amount of purchase, such as only a few grams, is mostly for scientific research and exploration. Due to cost sharing such as preparation and packaging, the price per gram is often higher; if a large amount of purchase is made, up to several kilograms or even several tons, the unit price may be greatly reduced due to the scale effect.
Third, the market supply and demand situation determines the price. If the demand increases sharply for a while, but the supply is limited, if a new drug is suddenly needed for a large amount of this product, the price will rise; on the contrary, if the supply is abundant, the demand is flat, and the price may stabilize or drop.
Fourth, the pricing of different suppliers also varies. Well-known large factories, due to quality control, brand reputation and other factors, the price may be high; while some small factories, in order to compete for market share, the price may have advantages, but the quality may need to be carefully inspected.
According to past market speculation, laboratory small packages, with a purity of about 98%, the price per gram may be in the tens of yuan; if they are industrial grade, large-scale purchases, the price per ton may be in the range of tens of thousands of yuan. However, this is only a rough estimate. To know the exact price, you need to consult chemical raw material suppliers, chemical trading platforms, etc. to obtain real-time and accurate quotations.