2 Aminoethylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-aminoethylpyridine

    Specifications

    HS Code

    258630

    Name 2 - aminoethylpyridine
    Molecular Formula C7H10N2
    Molar Mass 122.17 g/mol
    Appearance Colorless to yellow - brown liquid
    Odor Characteristic amine - like odor
    Solubility In Water Soluble
    Density 0.986 g/cm³
    Boiling Point 222 - 224 °C
    Flash Point 93 °C
    Pka ~9.3

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    Frequently Asked Questions

    As a leading 2-aminoethylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 2-aminoethylpyridine?
    2-Aminoethylpyridine is also an organic compound. Its molecule contains the structure of a pyridine ring and an aminoethyl group, and this unique structure gives it a variety of chemical properties.
    In terms of alkalinity, the pyridine ring is weakly basic, and the lone pair of electrons on the nitrogen atom can bind protons, while the amino group in the aminoethyl group is also basic and can accept protons. Therefore, 2-aminoethylpyridine is alkaline as a whole and can form salts with acids. For example, it reacts with hydrochloric acid to form a corresponding hydrochloride salt. This reaction is often used for the purification and analysis of this compound.
    Its nucleophilicity is also significant. The amino group of the aminoethyl group is an electron-rich group, which has nucleophilic ability and can undergo nucleophilic substitution reactions with electrophilic reagents. If it encounters a halogenated hydrocarbon, the nitrogen atom of the amino group will attack the carbon atom of the halogenated hydrocarbon, and the halogen atom will leave to form a new nitrogen-containing compound. This reaction is often used in organic synthesis to construct carbon-nitrogen bonds to prepare more complex organic molecules.
    2 -aminoethylpyridine also has certain coordination ability. Both the pyridine ring and the nitrogen atom of the amino group can provide lone pairs of electrons to coordinate with metal ions to form metal complexes. These complexes have important applications in the field of catalysis. For example, some metal complexes can be used as catalysts to promote the progress of specific organic reactions. Their structures can be modulated and can affect the activity and selectivity of the reaction.
    In addition, due to the conjugated system in its structure, 2-aminoethylpyridine has characteristic absorption in the ultraviolet-visible region, which can be used for qualitative and quantitative analysis, which is of great value in the field of chemical analysis. In short, 2-aminoethylpyridine is rich in chemical properties and has important uses in many fields such as organic synthesis, catalysis, and analysis.
    What are the main uses of 2-aminoethylpyridine?
    2-Aminoethylpyridine, or 2-aminoethylpyridine, is widely used and has important applications in many fields.
    In the field of organic synthesis, it often acts as a key intermediate. Due to its unique chemical structure, it can participate in a variety of chemical reactions and help to construct complex organic molecular structures. With the activity of amino groups and pyridine rings, it can be combined with many reagents by nucleophilic substitution, condensation and other reactions, providing convenience for the creation of organic compounds with specific properties and structures.
    In the field of pharmaceutical chemistry, 2-aminoethylpyridine also plays an important role. Because of its specific relationship between structure and biological activity, it is often used in the design and development of new drugs. Or its structure can be modified to optimize the affinity and selectivity of drugs to specific targets, improve drug efficacy, reduce toxic and side effects, and play a key role in the process of new drug creation.
    Furthermore, in the field of materials science, 2-aminoethylpyridine also has applications. Or it can participate in the synthesis of some polymer materials, endowing materials with special properties, such as improving the solubility, stability, and conductivity of materials, providing new ways and methods for the development of new functional materials.
    In short, 2-aminoethylpyridine plays an important role in organic synthesis, drug development, and materials science. With the continuous development of science and technology, its application prospects will also be broader.
    What are 2-aminoethylpyridine synthesis methods?
    The synthesis method of 2-aminoethyl pyridine has existed in ancient times, and the method has been evolving with the passage of time. In the past, the synthesis of this compound often followed the following path.
    First, pyridine was used as the initial material to react with halogenated ethane under the catalysis of bases. Bases, such as potassium carbonate and sodium carbonate, can provide a suitable alkaline environment for the reaction. The nitrogen atom of pyridine is nucleophilic, and the halogen atom of halogenated ethane is active. The two easily interact to form a carbon-nitrogen bond. During this process, the halogen ions leave, resulting in the formation of the precursor of 2-aminoethylpyridine. However, the reaction conditions need to be carefully controlled. Temperature and the proportion of reactants all affect the purity and yield of the product.
    Second, vinyl pyridine is synthesized by addition reaction. Vinyl pyridine is reacted with ammonia or compounds containing amino groups in the presence of suitable catalysts. Commonly used catalysts include transition metal complexes, such as palladium and nickel complexes. The catalyst can reduce the activation energy of the reaction, promote the addition of vinyl and amino groups, and successfully introduce aminoethyl groups. However, the choice and dosage of catalysts depend on the reaction rate and selectivity.
    Third, the compound containing the structure fragments of pyridine and aminoethyl is used as the starting material, and 2-aminoethylpyridine is obtained by the method of functional group conversion. For example, the pyridine derivative containing a suitable protecting group is connected to a group that can be converted into aminoethyl, and then the deprotecting group step is used to make the target compound present. This approach requires familiarity with the selection of protecting groups and the conditions for deprotection to ensure that the reaction is carried out accurately without affecting the structure of pyridine and aminoethyl.
    All synthetic methods have their own advantages and disadvantages. According to actual needs, factors such as raw material availability, difficulty of reaction conditions, product purity and yield should be weighed, and appropriate methods should be carefully selected to efficiently synthesize 2-aminoethylpyridine.
    2-aminoethylpyridine What are the precautions during storage and transportation?
    2-Aminoethylpyridine is an organic compound. When storing and transporting, many points need careful attention.
    Bear the brunt, and the storage environment is crucial. It should be placed in a cool and ventilated place, away from fire and heat sources. This is because it is flammable, high temperature or open flame is prone to danger. The warehouse temperature should not exceed 37 ° C to prevent excessive temperature from causing its volatilization to increase and increase safety risks.
    Furthermore, be sure to ensure that the package is well sealed. 2-Aminoethylpyridine is exposed to air, or interacts with moisture, oxygen, etc., resulting in quality deterioration. Sealed packaging can effectively isolate external factors and maintain its chemical stability.
    When transporting, it should be carried out in accordance with the regulations of dangerous chemicals. Because of its toxicity and corrosiveness, the transportation vehicle must be affixed with corresponding warning signs to ensure that the transporter is aware of its danger and equipped with emergency treatment equipment.
    The handling process also needs to be lightly loaded and unloaded, and must not be operated brutally. 2-Aminoethylpyridine leaks due to severe vibration, impact or damage to the package, polluting the environment and endangering the safety of personnel.
    In addition, the storage and transportation area should be kept away from oxidants, acids and other substances. 2-Aminoethylpyridine comes into contact with it, or causes severe chemical reactions, causing serious consequences such as fire and explosion.
    In conclusion, the storage and transportation of 2-aminoethylpyridine must be carried out in strict accordance with regulations, paying attention to the environment, packaging, transportation methods, and isolation from other substances to ensure personnel safety and material quality.
    2-aminoethylpyridine impact on the environment and human health
    2-Aminoethylpyridine is an organic compound. Its impact on the environment and human health cannot be ignored.
    In the environment, if 2-aminoethylpyridine is released outside, it may affect water bodies, soils, and atmospheres. In water bodies, it may interfere with the normal life of aquatic organisms. Aquatic organisms depend on the purity and balance of water bodies. The entry of this compound may break its ecological balance, causing the growth and reproduction of organisms to be hindered. In soil, it may change the chemical properties of soil, affect the activity of soil microorganisms, and then be detrimental to plant growth. As for the atmosphere, its volatilization in the air or participation in atmospheric chemical reactions has adverse effects on air quality.
    2-Aminoethylpyridine may be toxic to human health. It enters the human body through inhalation, ingestion or skin contact, or damages human organs. It may irritate the respiratory tract, causing cough, asthma and other symptoms. If ingested, it may hurt the stomach, and there is a risk of nausea and vomiting. And long-term exposure may cause allergies to the skin, redness, swelling, itching, etc. What's more, studies have also suspected that it has potential harm to the human nervous system and reproductive system. Although it has not been fully confirmed, it should not be ignored. Therefore, when using and handling this compound, be careful and strictly follow safety procedures to protect the environment and human health.