2-AMINOBENZOYL PYRIDINE

2 - AMINOBENZOYL + PYRIDINE is a chemical term, and its chemical structure is expressed as follows:
In "2 - AMINOBENZOYL", "BENZOYL" is a benzoyl group, which is formed by connecting a phenyl group to a carbonyl group, namely $C_6H_5 - CO - $. And "2 - AMINO" indicates that an amino group ($- NH_2 $) is connected to the benzoyl ring at position 2, so the structure of 2 - AMINOBENZOYL is the amino group at position 2 of the benzoyl ring, and the rest are benzoyl structures.
"PYRIDINE" is pyridine. Pyridine is a six-membered heterocyclic compound containing a nitrogen atom. Its structure is a six-membered ring, the nitrogen atom is in the ring, and the carbon atom and the nitrogen atom on the ring are alternately connected in the form of single and double bonds. The chemical formula is $C_5H_5N $.
If 2-AMINOBENZOYL is associated with PYRIDINE, it may be that the two chemically react to form a new compound. Or in a specific reaction system, 2-AMINOBENZOYL is connected to the pyridine ring as a substituent. For example, through suitable chemical reaction conditions, a certain activity check point of 2-AMINOBENZOYL reacts with a certain position on the pyridine ring, thereby constructing a substance with a new chemical structure and properties. However, it is difficult to know the specific chemical structure precisely based on the expression "2-AMINOBENZOYL + PYRIDINE". It is necessary to combine more information such as reaction conditions, reaction mechanism and experimental data to accurately determine the specific chemical structure involved.

2-Aminobenzoyl pyridine, this substance has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, it can be cleverly combined with other compounds through specific chemical reactions to construct molecules with specific pharmacological activities, which is of great significance for the development of new antibacterial and anti-inflammatory drugs.
In the field of materials science, it also plays an important role. It can be used to prepare functional materials, such as organic optoelectronic materials. With its own electronic structure characteristics, it participates in the regulation of photoelectric properties of materials, laying the foundation for the creation of high-performance Light Emitting Diodes, solar cells and other materials. < Br >
In the field of chemical research, as a building block for organic synthesis, chemists can expand the path of organic synthesis by modifying and reacting various functional groups, enrich the types of organic compounds, and help the creation and reaction mechanism of new compounds.
In chemical production, it is an important raw material for the production of a variety of fine chemicals. After a series of chemical reactions, it is converted into products for different purposes, enriching the product line for the chemical industry and enhancing the added value of products.
Due to its unique structure, this compound has shown significant application value in many fields such as medicine, materials, scientific research and chemical industry, promoting continuous innovation and development in various fields.

The synthesis methods of 2-aminobenzoyl pyridine have existed in ancient times and are of various kinds. The main ones are selected and briefly described as follows.
First, benzoic acid derivatives and pyridine derivatives are used as starting materials and are obtained by condensation reaction. First, benzoic acid is suitably substituted, an amino group is introduced, and then a condensation reaction is carried out with pyridine derivatives under specific reaction conditions, catalyzed by a condensation agent. This condensation agent, or dicyclohexyl carbodiimide (DCC), is reacted in a suitable solvent, such as dichloromethane, N, N-dimethylformamide (DMF), in a temperature-controlled reaction to obtain the target product.
Second, starting from anthranilic acid, through acylation reaction, anthranilyl chloride is first prepared, and this step is often combined with chlorination reagents such as thionyl chloride. The obtained anthranilyl chloride is then reacted with pyridine in the presence of acid binding agents. The acid binding agent can be selected as triethylamine, etc., and can also be synthesized in an organic solvent.
Third, palladium-catalyzed cross-coupling reaction is also a feasible way. Select suitable halogenated pyridine and amino-containing benzoyl boric acid or borate ester, and react in the presence of a base and a suitable reaction system under the catalysis of palladium catalysts such as tetra (triphenylphosphine) palladium. The base can be selected from potassium carbonate, etc., and the reaction solvent can be selected from toluene, dioxane, etc. According to the specific situation, through this reaction, 2-aminobenzoyl pyridine can also be successfully synthesized.
All synthesis methods have their own advantages and disadvantages, and must be carefully selected according to the availability of raw materials, the difficulty of reaction, and the purity requirements of the product. The ideal synthesis effect can be achieved.

2-Aminobenzoyl pyridine has unique physical and chemical properties. Looking at its physical properties, at room temperature, this substance is mostly solid and has a certain crystalline form. The appearance may be white to light yellow crystalline powder. Due to its regular molecular structure, the intermolecular forces are arranged in an orderly manner. Its melting point is quite high, about [X] ° C. The high melting point is due to the existence of strong interactions between molecules, such as hydrogen bonds, van der Waals forces, etc. To break these effects, more energy is required, so the melting point is not low.
As for its solubility, it has a certain solubility in common organic solvents such as ethanol and acetone. Ethanol and acetone molecules can form specific interactions with 2-aminobenzoyl pyridine molecules, such as hydrogen bonds, dipole-dipole interactions, etc., so that the substance can be dispersed. However, in water, the solubility is relatively small, because the polarity of water is limited to the polarity matching of the substance molecule, and the intermolecular forces are difficult to effectively fit with water molecules.
In terms of its chemical properties, both the amino group and the benzoyl group of 2-aminobenzoyl pyridine have active chemical activities. Amino groups can undergo acylation, alkylation and other reactions. When acylated, the lone pair electrons on the nitrogen atom of the amino group are strongly attractive to the electrophilic reagent, and easily react with the acylating reagent to form amide derivatives. The same is true for alkylation, and the nitrogen atom can capture alkyl positive ions to form new carbon-nitrogen bonds. The carbonyl group of the benzoyl group is electrophilic and can undergo addition reactions with nucleophilic reagents, such as with alcohols under acid catalysis, to form ester compounds. The pyridine ring is also not inert, because of its aromaticity, it can undergo electrophilic substitution reactions, and because of the electronegativity of the pyridine ring nitrogen atom, the electron cloud density distribution on the pyridine ring is uneven, and the substitution reaction often occurs at a specific location. In conclusion, the physical and chemical properties of 2-aminobenzoylpyridine are determined by its unique molecular structure, and it has a wide range of uses in organic synthesis and other fields.

2-Aminobenzoyl pyridine is on the market, and its price range is difficult to determine. The price of this compound often changes due to multiple reasons.
First, the quality is crucial. If its purity is very high and there are very few impurities, it is suitable for high-end fields such as fine chemicals and pharmaceutical research and development, and the price will be high; on the contrary, if the purity is slightly lower, it can only be used for general industrial purposes, and the price will be low.
Second, the trend of supply and demand determines its price. If there are many people in the market, but the supply is small, if the demand for a new drug is greatly increased, and the manufacturer is temporarily unable to respond, the price will rise; if the supply exceeds the demand, the price will automatically decline.
Third, manufacturers and channels also have an impact. Different manufacturers have different pricing due to different production processes and cost control. And through different sales channels, such as purchasing directly from manufacturers, or through multi-level distributors, the price is also different.
Fourth, geographical factors cannot be ignored. Different regions, due to differences in transportation costs, local market environment, etc., prices also fluctuate.
To sum up, in today's market conditions, the price of 2-aminobenzoylpyridine, or from hundreds to thousands of yuan per kilogram, is difficult to determine the exact price range. To know the details, you need to consult the relevant chemical product suppliers or observe it in the market.