2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid ethyl ester

This is the name of 2-amino-7- (1-methylethyl) -5-oxo-5H-[ 1] benzopyrano [2,3-b] pyridine-3-carboxylic acid ethyl ester. Looking at its name, in order to deduce its chemical structure, it is necessary to analyze it according to the nomenclature rules of organic chemistry.
"2-amino", indicating that the amino group is attached to the second position of the main structure; "7- (1-methylethyl) ", which is isopropyl, connected to the seventh position; "5-oxo-5H- [1] benzopyrano [2,3-b] pyridine", which is the main ring structure, which is formed by the combination of benzopyran and pyridine, and the 5th position has a carbonyl group; "3-carboxylate ethyl ester", that is, the 3rd position is connected with a carboxylic acid ethyl ester group.
According to this analysis, its chemical structure is roughly as follows: benzopyranopyridine is used as the parent nucleus, with amino group at No. 2, isopropyl group at No. 7, ethyl carboxylate group at No. 3, and carbonyl group at No. 5. In the
structure, the parent nucleus of benzopyranopyridine provides a rigid framework, and the substituents such as amino group, isopropyl group, ethyl carboxylate and carbonyl group endow the compound with specific chemical properties and reactivity. This structure may be of great significance in the field of organic synthesis and medicinal chemistry, because different substituents can affect the biological activity, solubility and stability of compounds.

2-Amino-7- (1-methylethyl) -5-oxo-5H - [1] benzopyrano [2,3-b] pyridine-3-carboxylic acid ethyl ester, which is an organic compound. Its physical properties are as follows:
In normal condition, it is a crystalline solid. Due to the existence of various forces between molecules, such as hydrogen bonds, van der Waals forces, etc., the molecules are arranged in an orderly manner and crystallized. Its color is either almost colorless or white, and it covers the absence of too many chromophores that can cause significant color changes in its structure.
In terms of melting point, the specific structure of the compound determines the size of the intermolecular force, making it have a specific melting point. However, the specific value needs to be accurately determined by experiments, and there may be differences due to different purity and experimental conditions. Generally speaking, the melting point of compounds containing benzopyran and pyridine structures is usually within a certain range. This compound may be between 150 and 250 ° C. Because the benzene ring and heterocyclic system enhance the rigidity of the molecule, more energy is required to overcome the intermolecular force caused by lattice damage.
In terms of solubility, it is an ester compound with certain hydrophobicity. It has poor solubility in solvents with strong polarity such as water, because it is difficult to form effective interactions between water molecules and the compound molecules. However, in common organic solvents, such as dichloromethane, chloroform, acetone, etc., the solubility may be better. This is because these organic solvents and compound molecules can be miscible through van der Waals forces or other weak interactions. Taking dichloromethane as an example, its non-polar part can interact with the benzene ring, alkyl group and other non-polar regions in the compound to help it dissolve.
Density is also an important physical property. Although the exact value needs to be determined experimentally, it can be inferred from the structure and similar compounds. Because the molecule contains benzene ring, pyridine ring and ester group, the relative molecular weight is large, and the structure is compact, and the density may be greater than that of water, probably between 1.2 and 1.5 g/cm ³.
The speculation of the above physical properties is based on its chemical structure and the properties of similar compounds. To obtain accurate physical property data, rigorous experimental determination is still required.

To prepare 2-amino-7- (1-methylethyl) -5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate ethyl ester, the method of organic synthesis is often followed.
The first step is to use suitable starting materials and through condensation reaction to construct the basic structure of benzopyran and pyridine. If a phenolic compound with a specific substituent and a nitrogen-containing heterocyclic precursor are selected, under appropriate reaction conditions, a base is used as a catalyst to heat the reaction in an organic solvent to promote the condensation of the two. This process requires fine regulation of the reaction temperature, time and material ratio to increase the yield of the target intermediate.
Next step, modify the resulting intermediate. Or introduce a specific substituent, which can be achieved by nucleophilic substitution, electrophilic substitution and other reactions. For example, a reagent containing 1-methylethyl group is reacted with the intermediate under suitable conditions to achieve the introduction of 7-position 1-methylethyl group. Among them, the precise control of the reaction activity check point and the optimization of the reaction conditions are very critical to avoid unnecessary side reactions.
Furthermore, the carboxyl functional group is esterified to obtain the ethyl ester form of the target product. Ethanol is often used as an esterification reagent, and the reaction is carried out in a heated reflux state under acid catalysis. In this step, attention should be paid to the reversibility of the reaction. By removing the water generated by the reaction, the reaction can be promoted in the direction of ester formation.
During the whole synthesis process, the products of each step of the reaction need to be characterized in detail by a variety of analytical methods, such as nuclear magnetic resonance, mass spectrometry, etc., to confirm the structure and purity of the products, and to carefully optimize each step of the reaction, in order to efficiently and high-quality synthesis of 2-amino-7- (1-methylethyl) -5-oxo-5H-[ 1] benzopyrano [2,3-b] pyridine-3-carboxylate ethyl ester.

2-Amino-7- (1-methylethyl) -5-oxo-5H - [1] benzopyrano [2,3-b] pyridine-3-carboxylate ethyl ester, which is very important in the field of medicine. When creating new antimalarial drugs, it shows extraordinary potential. Due to the raging of malaria parasites, it is very harmful, and this compound has a unique structure, or it can block the key links such as metabolism and reproduction of malaria parasites, so as to achieve anti-malaria effect.
Furthermore, it has also emerged in the field of anti-tumor drug research and development. Tumor diseases are very difficult, and many patients are deeply affected by them. This compound may be able to regulate the signaling pathway of tumor cells, inhibit the proliferation of tumor cells, induce their apoptosis, and find a new way to overcome the problem of tumors.
Not only that, but it also plays a role in the exploration of drugs for neurological diseases. Neurological diseases such as Alzheimer's disease and Parkinson's disease seriously affect the quality of life of patients. This compound may regulate the release and transmission of neurotransmitters, improve the function of nerve cells, and provide a new opportunity for the treatment of such diseases. In conclusion, 2-amino-7- (1-methylethyl) -5-oxo-5H- [1] benzopyrano [2,3-b] pyridine-3-carboxylate ethyl ester has significant value in many aspects of pharmaceutical research and development, and is expected to make great contributions to human health.

2-Amino-7- (1-methylethyl) -5-oxo-5H - [1] benzopyrano [2,3-b] pyridine-3-carboxylate ethyl ester, this is an organic compound. When storing and transporting, many matters must be paid attention to.
First storage environment. Should be placed in a cool, dry and well ventilated place. If the ambient humidity is too high, the compound may be damp, affecting its quality, and even chemical reactions. Excessive temperature may also promote the decomposition and deterioration of the compound. Be sure to keep away from fire and heat sources, because it has certain chemical activity, in case of open flame, hot topic or cause danger.
Furthermore, storage needs to be classified. Do not mix with oxidants, acids, alkalis and other substances. Because of its special chemical structure, contact with these substances, or cause severe chemical reactions, causing serious consequences such as combustion and explosion. The storage place should be equipped with suitable materials for containing leaks to prevent accidental leakage.
The transportation process should not be ignored. It is necessary to ensure that the container is well sealed to prevent leakage during transportation. When handling, it should be handled lightly to avoid damage to the packaging container due to brutal loading and unloading. Vehicles used for transportation should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. During driving, keep away from densely populated areas and dangerous areas such as fire sources. Transport personnel also need to have professional knowledge and know the characteristics of the compound and emergency treatment methods, so as to ensure the safety of storage and transportation.