2-amino-6-cyanopyridine

2-Amino-6-cyanopyridine is an important organic compound with key uses in many fields.
First, in the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of various drugs. Due to the unique chemical activity of the pyridine ring with cyano and amino groups, it can participate in various chemical reactions to construct drug molecular structures with specific biological activities. For example, in the development of some antibacterial and antiviral drugs, 2-amino-6-cyanopyridine may play an important role. Through chemical modification and synthesis steps, it can be converted into pharmaceutical components with therapeutic effects on specific diseases.
Second, in the field of materials science, it also has outstanding performance. It can be used to prepare functional materials, such as organic optoelectronic materials. Due to its molecular structure properties, it may endow materials with unique optical and electrical properties. For example, in the research and development of organic Light Emitting Diode (OLED) materials, 2-amino-6-cyanopyridine can be rationally designed and modified to optimize the key performance indicators such as luminous efficiency and stability of materials, thus promoting the progress of display technology.
Furthermore, in the field of pesticide chemistry, its status should not be underestimated. It can be used as an important raw material for the synthesis of new pesticides. Pyridine rings and linked groups can endow pesticides with specific biological activities, which can be used to control crop diseases and pests, and ensure the yield and quality of agricultural production. Through structural modification and optimization, it is expected to develop new pesticide products with high efficiency, low toxicity and environmental friendliness.
In summary, 2-amino-6-cyanopyridine has shown broad application prospects in many fields such as medicine, materials, and pesticides due to its unique chemical structure, and plays a crucial role in promoting technological development and innovation in related fields.

The synthesis method of 2-amino-6-cyanopyridine is described in ancient books and is described below.
First, 2-aminopyridine is used as the starting material. First, it is heated with a suitable cyanide reagent, such as cuprous cyanide, under specific reaction conditions. An appropriate solvent, such as dimethylformamide (DMF), is required, which can promote the reaction. The reaction system must be protected by an inert gas to prevent the raw material and product from being oxidized. Control the reaction temperature and time, usually at a higher temperature, about 100-150 ° C, for several hours before the cyanyl group can be successfully introduced into the 6 position of the pyridine ring to obtain 2-amino-6-cyanopyridine.
Second, pyridine derivatives can also be used as starters. Prepared by a multi-step reaction, a suitable substituent is introduced into the pyridine ring first, and this substituent needs to be able to be converted into cyano and amino groups in subsequent reactions. For example, the halogen atom is introduced first, and then the nucleophilic substitution reaction introduces the cyanide-containing group, and the amino group is introduced at the appropriate position through other reaction steps. In this process, each step of the reaction requires strict control of the reaction conditions, including the proportion of reactants, solvent selection, reaction temperature and time.
Third, there is a metal-catalyzed synthesis path. Appropriate metal catalysts, such as palladium catalysts, are selected to assist with specific ligands. The starting material is coupled with a metal-catalyzed coupling reaction to connect the cyano- and amino-containing fragments to the pyridine ring. This method requires precise regulation of the catalyst dosage, the pH of the reaction environment and other conditions to enable the reaction to proceed smoothly and efficiently synthesize 2-amino-6-cyanopyridine.

2-Amino-6-cyanopyridine is an organic compound whose physical properties are worth exploring. This substance is mostly in a solid state at room temperature. Looking at its appearance, it may be a white to off-white crystalline powder. Due to the regular molecular structure, the intermolecular forces are arranged in an orderly manner, and it is easy to form a solid state.
When it comes to the melting point, it is about a certain range. Due to the interaction between molecules such as hydrogen bonds and van der Waals forces, a specific energy is required to break the lattice and turn the solid state into a liquid state. Its boiling point is also determined by factors such as intermolecular forces and molecular weights. The intermolecular forces are strong and the molecular weights are large, so a higher temperature is required to overcome the intermolecular attractive forces and make it gasify. < Br >
In terms of solubility, its solubility in water is limited, because its molecules contain cyanide and amino groups. Although amino groups can form hydrogen bonds with water, cyanyl groups have strong hydrophobicity, resulting in poor water solubility as a whole. However, in organic solvents such as ethanol and dichloromethane, the solubility may be better, because the organic solvent and the compound molecules can form a similar and soluble effect, which is conducive to its dispersion and dissolution.
Its density is also an important physical property, which is determined by the molecular weight and the occupied space. It is relatively stable under specific conditions, reflecting the degree of tight accumulation of molecules. In addition, the compound may have a certain odor, but the content varies with the environment, and the odor may be light or imperceptible. In conclusion, the physical properties of 2 - amino - 6 - cyanopyridine are profoundly influenced by molecular structure and interaction, and are of great significance in chemical synthesis, materials science and other fields.

2-Amino-6-cyanopyridine, the price of this product in the market varies according to time, place and supply and demand changes. Looking at the state of the market in the past, its price fluctuations were like waves.
In the past, when raw materials were abundant and the supply was smooth, the price may stabilize and be slightly lower. If raw materials are scarce, supply is stagnant, and demand is strong, the price will rise, like a flying canopy.
According to the situation in the past few years, its price often hovers between [X1] yuan and [X2] yuan per kilogram. However, in the event of changes in the chemical industry and the impact of policies and decrees, there will also be sharp fluctuations. If new production techniques come out, resulting in a large increase in production capacity, the price may drop; conversely, if environmental regulations become stricter and production is limited, the price will rise.
And the regional differences in the market also affect its price. Near the origin of raw materials, or due to the convenience of transportation and cost reduction, the price is slightly lower; in remote places, due to the increase in logistics costs, the price may be slightly higher. Furthermore, the buyer's purchase volume is also the key. Those who purchase in bulk may get preferential prices due to large quantities; those who purchase in small quantities may get slightly higher prices.
Therefore, in order to know the exact price, it is necessary to observe the supply and demand of the market, the market conditions of raw materials, and regional factors in real time.

2-Amino-6-cyanopyridine is a chemical substance. When storing and transporting, many matters need to be paid attention to.
In terms of storage, the first environment. It should be placed in a cool, dry and well-ventilated place. This substance is quite sensitive to temperature and humidity, and high temperature and humidity can easily cause it to deteriorate. If the temperature is too high, or it may cause a chemical reaction, causing its chemical properties to change; if the humidity is too high, it may absorb moisture and affect the purity and stability.
Furthermore, it needs to be kept away from fire and heat sources. Because it has certain chemical activity, it is at risk of an open flame, hot topic or combustion explosion. And it should be stored separately from oxidizing agents, acids, bases, etc. to prevent mutual reaction. Because its chemical structure contains amino and cyano groups, contact with acid and alkali and other substances is prone to chemical reactions, damage the substance itself, and may also produce dangerous products.
When transporting, the packaging must be solid. Select appropriate packaging materials to ensure that it is not damaged or leaked during transportation. If it is not packaged properly, once it leaks, it may not only waste resources, but also pollute the environment and endanger human health.
Transportation vehicles also need to meet safety requirements. Corresponding fire fighting equipment and leakage emergency treatment equipment should be equipped to prevent emergencies during transportation. Drivers and escorts need to undergo professional training, familiar with the dangerous characteristics and emergency treatment methods of 2-amino-6-cyanopyridine, and abide by the operating procedures during transportation to ensure the safety of transportation.