2 Amino 5 Pyridinecarboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-5-PyridineCarboxylic Acid

    Specifications

    HS Code

    825032

    Name 2 - Amino - 5 - PyridineCarboxylic Acid
    Molecular Formula C6H6N2O2
    Molar Mass 138.12 g/mol
    Appearance Solid (usually white to off - white)
    Odor Odorless (generally)
    Melting Point ~240 - 245 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Pka Value pKa1 (for carboxylic acid) ~3 - 4; pKa2 (for amino group) ~9 - 10
    Acidity Weakly acidic due to carboxylic acid group
    Basicity Weakly basic due to amino group
    Stability Stable under normal conditions, but may react with strong acids, bases or oxidizing agents

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    General Information
    Where to Buy 2-Amino-5-PyridineCarboxylic Acid in China?
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    Frequently Asked Questions

    As a leading 2-Amino-5-PyridineCarboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Amino-5-PyridineCarboxylic Acid?
    2-Amino-5-pyridinecarboxylic acid, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to assist in the synthesis of many drugs. For example, some drugs with specific biological activities, through clever design and reaction, 2-amino-5-pyridinecarboxylic acid can be transformed into an important structural unit, laying the foundation for the efficacy of drugs.
    In the field of materials science, it also has important functions. It may participate in the preparation of new materials, giving materials different properties by virtue of its unique chemical structure. For example, in the synthesis of specific polymer materials, the addition of this substance may change the mechanical properties and thermal stability of the material.
    In agricultural chemistry, its role should not be underestimated. Or used in the synthesis of pesticides, plant growth regulators, etc. In pesticide synthesis, its structural characteristics can enhance the effect of pesticides on target organisms, improve the pertinence and effectiveness of pesticides; in the synthesis of plant growth regulators, it can affect the process of plant growth and development, and help crops with high quality and high yield.
    In short, 2-amino-5-pyridinecarboxylic acid plays an important role in many fields. With its unique chemical properties, it provides assistance for the development of various fields and promotes the continuous innovation and progress of related technologies and products.
    What are the physical properties of 2-Amino-5-PyridineCarboxylic Acid?
    2-Amino-5-pyridinecarboxylic acid, its physical properties are as follows:
    This substance is mostly in solid form at room temperature, but the specific state may vary slightly due to purity and crystallization conditions. Its melting point is one of the important physical properties, about a specific temperature range, this temperature can be a key indicator for identifying and purifying the substance.
    In terms of solubility, in polar solvents, such as water, it has a certain solubility, but the solubility may not be very high. The degree of solubility is related to factors such as water temperature. When the water temperature increases, the solubility may increase to a certain extent. In organic solvents, such as ethanol, acetone, etc., the solubility also varies, and in some organic solvents, the solubility is slightly better, which is very important for its application in different chemical reaction systems.
    2-Amino-5-pyridinecarboxylic acid has certain stability, and can maintain its chemical structure unchanged for a certain period of time under ordinary environmental conditions. In case of extreme conditions such as high temperature, strong acid, and strong base, the chemical structure may change, triggering decomposition or other chemical reactions.
    In its molecular structure, amino groups interact with pyridine rings and carboxyl groups, giving the substance a certain acidity and alkalinity. The carboxyl group can release protons and is acidic; the amino group can accept protons and is alkaline. This acid-base characteristic can play a key role in many chemical reactions and biochemical processes, affecting its reactivity and binding ability with other substances.
    Furthermore, its spectral characteristics are also worthy of attention. In infrared spectroscopy, the chemical bonds on carboxyl groups, amino groups and pyridine rings all produce absorption peaks at specific wave numbers. These absorption peaks are like the "fingerprint" of a substance, which can be used to accurately identify the substance and determine the integrity of its chemical structure. In ultraviolet spectroscopy, due to the conjugated structure of the pyridine ring, specific absorption bands will appear, which can be used to quantitatively analyze the concentration of the substance in solution.
    In summary, the many physical properties of 2-amino-5-pyridinecarboxylic acid lay the foundation for its application in chemical synthesis, drug development, materials science and many other fields.
    2-Amino-5-PyridineCarboxylic Acid is chemically stable?
    2-Amino-5-pyridine carboxylic acid, this is an organic compound. The stability of its chemical properties depends on many factors.
    Structurally, the pyridine ring is a stable six-membered heterocyclic ring structure, and the nitrogen atom endows it with certain basicity and aromaticity. The 2-position amino group and the 5-position carboxyl group introduce specific reactivity check points for the compound. The amino group is nucleophilic, while the carboxyl group is acidic. Both can participate in various chemical reactions.
    At the stability level, the compound can remain relatively stable in the conventional environment without specific chemical reaction conditions. However, in the strong acid and alkali environment, its stability may be affected. For example, in strong acids, carboxylic groups or protonated, amino groups may also be protonated, resulting in changes in molecular charge distribution and affecting their chemical properties; under strong alkali conditions, carboxylic groups can form salts, amino groups or participate in nucleophilic substitution and other reactions, all of which play a role in their stability.
    Temperature is also a key factor. Moderate temperature changes may have limited impact on its stability. However, at high temperatures, intramolecular or intermolecular reactions may be triggered, resulting in structural changes and reduced stability.
    The redox environment cannot be ignored. If there are strong oxidizing agents or reducing agents, 2-amino-5-pyridine carboxylic acids may participate in redox reactions, destroying the original structure and reducing stability. Overall, the stability of 2-amino-5-pyridinecarboxylic acids is not absolute, and its stability may change under specific chemical and physical conditions.
    What are the synthetic methods of 2-Amino-5-PyridineCarboxylic Acid?
    To prepare 2-amino-5-pyridinecarboxylic acid, there are many methods, each with its advantages and disadvantages, which should be examined in detail.
    First, it can be obtained from the hydrolysis of 5-cyanopyridine-2-amino group. In this way, 5-cyanopyridine-2-amino group is used as the starting material, and in a suitable acid-base environment, the cyano group is hydrolyzed to carboxyl groups. If a strong base is used as the catalyst, it is heated to reflux to promote its hydrolysis. The advantage of this approach is that the raw materials are relatively easy to find, and the reaction path is relatively clear; however, the lack of it is also obvious, the hydrolysis conditions may be severe, and the product separation may be hindered, requiring fine handling to obtain a pure product.
    Second, take 2-nitro-5-pyridinecarboxylic acid as the starting material and prepare it by reduction. Take 2-nitro-5-pyridinecarboxylic acid first, and use a suitable reducing agent, such as a combination of metal and acid, or a catalytic hydrogenation method to convert the nitro group to an amino group. If catalytic hydrogenation is used, choose a suitable catalyst, such as palladium carbon, and react at a certain temperature and pressure. The advantage of this method may be that the purity of the product may be higher, and it is better for the environment; however, catalytic hydrogenation requires specific equipment, which may increase the cost, reduce the metal and acid, or generate more waste, which is harmful to environmental protection.
    Third, it is constructed from pyridine derivatives through multi-step reactions. First, pyridine is used as a base, and the groups required for amino and carboxyl groups are introduced according to the principle of electrophilic substitution or nucleophilic substitution, and then the series of conversions are carried out to obtain the target product. This route can be designed on demand, which is highly flexible; however, there are many steps, and the reaction conditions are not easy to control, and the total yield may be affected. < Br >
    All these methods are the way to prepare 2-amino-5-pyridinecarboxylic acid. In practice, the optimal method is selected according to the factors such as raw material availability, cost, equipment conditions and environmental protection, so as to achieve the purpose of efficient preparation.
    What is the price range of 2-Amino-5-PyridineCarboxylic Acid in the market?
    2-Amino-5-pyridinecarboxylic acid, what is the price between markets, I will describe it in detail. Looking at the records of past transactions, its price is not uniform, and often varies due to quality, quantity, and times.
    If you buy a small amount, the price per gram of high quality may be in the tens of gold. This is mostly for scientific research, and the purity requirements are quite strict, so the price is high.
    If you buy in bulk, merchants often respond at preferential prices. The larger the batch, the lower the price. In kilograms, the price per kilogram may drop to hundreds of gold. Because of the purchase in bulk, merchants can save all kinds of expenses, so they can make profits.
    Furthermore, the situation is also about its price. If the production of raw materials changes, or the market demand increases greatly, the price also fluctuates. If raw materials are scarce, and the demand exceeds the supply, the price will rise; on the contrary, the price may stabilize and decline.
    However, if you want to know the real-time price, you should consult merchants in the industry, or look at professional trading platforms, in order to obtain accurate numbers for comprehensive calculation.