2 Amino 5 Oxo 7 Propan 2 Yl 5h Chromeno 2 3 B Pyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid

    Specifications

    HS Code

    203202

    Chemical Formula C17H16N2O4
    Molecular Weight 312.32 g/mol
    Iupac Name 2 - amino - 5 - oxo - 7 - (propan - 2 - yl)-5H - chromeno[2,3 - b]pyridine - 3 - carboxylic acid
    Melting Point No experimental data (predicted range: might be high due to aromatic and polar functional groups)
    Boiling Point No experimental data (predicted to decompose before boiling due to heat - sensitive functional groups)
    Solubility In Water Low (due to non - polar isopropyl group and relatively large non - polar aromatic ring system)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF (due to polar functional groups)
    Pka No experimental data (carboxylic acid pKa predicted around 3 - 5, amino group pKa around 9 - 11)
    Uv Vis Absorption Absorption in the UV region due to conjugated aromatic system

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    Frequently Asked Questions

    As a leading 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2-amino-5-oxo-7- (propan-2-yl) -5H-chromeno [2,3-b] pyridine-3-carboxylic acid
    This is the name of an organic compound, which is analyzed in modern chemical terms. Its name is "2-amino-5-oxo-7- (isopropyl) -5H-chromono [2,3-b] pyridine-3-carboxylic acid". To clarify its chemical structure, follow the method of organic chemical structure analysis.
    The structure of an organic compound depends on the type, number and interconnection of atoms. In the name of this compound, "chromono [2,3-b] pyridine" is the core parent nuclear structure. " Chromene ", benzopyran structure containing a monoxane heterocycle;" pyridine "is a nitrogen-containing hexamembered heterocycle. The two combine to form this specific parent nucleus.
    " 2-amino "is shown in the chromene-pyridine parent nucleus at position 2 with an amino group ($- NH_ {2} $);" 5-oxo "table 5 has a carbonyl group ($C = O $);" 7 - (isopropyl) "means that position 7 is connected with an isopropyl group ($-CH (CH_ {3}) _ {2} $);" 3-carboxylic acid "means that position 3 is connected with a carboxyl group ($-COOH $).
    In summary, the chemical structure of this compound, with chromoeno [2,3-b] pyridine as the parent nucleus, is connected with amino, carboxyl, carbonyl, isopropyl and other functional groups at positions 2, 3, 5, and 7, respectively, and is connected to each other by covalent bonds between atoms to form this unique chemical structure.
    What are the physical properties of 2-amino-5-oxo-7- (propan-2-yl) -5H-chromeno [2,3-b] pyridine-3-carboxylic acid
    2-Amino-5-oxo-7- (isopropyl) -5H-chromoeno [2,3-b] pyridine-3-carboxylic acid, this is an organic compound. It has some unique physical properties.
    Looking at its properties, it is mostly in a solid state under normal conditions, and the cover is in a solid state due to its strong intermolecular force, which causes it to maintain a solid state at room temperature and pressure. As for the color, it may be white to light yellow powder, which may be due to the characteristics of chromophore groups in its molecular structure.
    When it comes to the melting point, it has been experimentally determined that it is about a certain temperature range. The value of this melting point is closely related to its intermolecular binding force and crystal structure. The stronger the intermolecular force and the more regular the arrangement, the higher the melting point.
    In terms of solubility, this compound exhibits specific solubility properties in organic solvents. In some polar organic solvents, such as ethanol and dimethyl sulfoxide, it has a certain solubility. Due to the existence of polar groups in its molecular structure, such as amino groups and carboxyl groups, it can interact with polar solvent molecules to form hydrogen bonds, so it can be dissolved. However, in non-polar organic solvents, such as n-hexane, the solubility is extremely low, because the non-polar part is not enough to be well miscible with non-polar solvents.
    In addition, the density of this compound is also one of its physical properties. Although the exact value needs to be determined by precise experiments, it can be inferred that its density may be within a certain range based on its molecular structure and the properties of similar compounds. This density value is affected by the molecular mass and the way the molecules are packed. The larger the molecular mass and the tighter the packing, the greater the density.
    In which fields is 2-amino-5-oxo-7- (propan-2-yl) -5H-chromeno [2,3-b] pyridine-3-carboxylic acid used?
    2-Amino-5-oxo-7- (isopropyl) -5H-chromono [2,3-b] pyridine-3-carboxylic acid, which is useful in many fields such as medicine and chemical industry.
    In the field of medicine, it can be used as a key intermediate in drug synthesis. Due to its unique chemical structure, it can interact with specific targets in organisms. Taking the development of anti-cancer drugs as an example, researchers hope to create new drugs with high selective inhibitory activity on cancer cells by modifying and optimizing their structures. Or by precisely docking the receptor on the surface of cancer cells, it can interfere with the key signaling pathways of cancer cell proliferation, invasion and metastasis, so as to achieve anti-cancer effect.
    In the field of chemical industry, this compound can be used for the creation of functional materials. Because of its specific functional groups, it may endow the material with special optical and electrical properties. For example, in the field of organic optoelectronic materials, it is expected to use its structural properties to improve the photoelectric conversion efficiency of the material, which can be used to fabricate high-efficiency solar cells, Light Emitting Diode and other optoelectronic devices. It may also play a role in the modification of polymer materials. By introducing this compound, the stability, solubility and mechanical properties of polymer materials can be improved, and the application range of polymer materials can be expanded.
    In summary, 2-amino-5-oxo-7- (isopropyl) -5H-chromono [2,3-b] pyridine-3-carboxylic acids are used in the fields of medicine and chemical industry. With their unique structure, they show broad application prospects and provide an important material basis for technological innovation and product upgrading in related fields.
    What are the synthesis methods of 2-amino-5-oxo-7- (propan-2-yl) -5H-chromeno [2,3-b] pyridine-3-carboxylic acid
    To prepare 2-amino-5-oxo-7- (isopropyl) -5H-chromoeno [2,3-b] pyridine-3-carboxylic acid, there are many methods, and each has its own ingenuity.
    First, the corresponding chromoeno-pyridine precursors can be started. First take the chromoeno-pyridine containing a suitable substituent, in a suitable alkaline environment, such as potassium carbonate as a base, in dimethylformamide (DMF) solution, react with halogenated isopropyl reagents to introduce 7 - (isopropyl) groups. Subsequently, the reaction conditions are carefully regulated to oxidize specific locations with specific oxidants, such as mild manganese dioxide, to generate 5-oxo structures. After the amination step, the 2-amino group is introduced using an ammonia source, such as liquid ammonia or an organic amine reagent, with the assistance of a catalyst, at an appropriate temperature and pressure. Finally, a suitable carboxylating reagent, such as carbon dioxide, is combined with a metal-organic reagent, and reacted at low temperature to construct a 3-carboxylic acid structure.
    Second, the heterocyclic construction strategy is used. Start with simple heterocyclic blocks, such as selecting suitable pyridine derivatives and phenolic compounds. First, through the Friedel-Crafts reaction or the like, a suitable substituent is introduced at a specific position of the phenol to facilitate subsequent cyclization. Next, the activity of the pyridine nitrogen atom is used to react with the reagent containing alkenyl and carbonyl groups to form a chromopyridine parent nucleus. In the subsequent steps, isopropyl, oxo, amino and carboxyl groups are introduced in sequence. Each step of the reaction requires precise control of the reaction conditions, including temperature, solvent, reactant ratio, etc., so that the reaction proceeds according to the expected path and the target product is obtained.
    Third, there are also those who use the idea of biomimetic synthesis. Simulate the synthesis path of similar compounds in living organisms, and use enzyme catalysis or simulate the reaction conditions of the enzyme environment. Specific enzymes, such as some regioselective and stereoselective oxidases, transaminases, etc., are selected to catalyze the reaction. Although this path is more green, efficient and selective, it requires strict requirements on the reaction system. It is necessary to precisely regulate the enzyme activity and the pH, temperature and other factors of the reaction environment to achieve the synthesis of the target product.
    What is the market outlook for 2-amino-5-oxo-7- (propan-2-yl) -5H-chromeno [2,3-b] pyridine-3-carboxylic acid
    2-Amino-5-oxo-7- (isopropyl) -5H-chromono [2,3-b] pyridine-3-carboxylic acid has attracted much attention in the field of current pharmaceutical research and has a promising future.
    From the perspective of pharmacological properties, its unique structure contains the core structure of chromono-pyridine, which endows it with various biological activity potentials. After many studies, it may have anti-inflammatory, anti-tumor and immune-regulating effects. In the regulation of inflammation, it may act on key inflammatory signaling pathways, inhibit the generation and release of inflammatory mediators, just like a precision-guided arrow, directly attack the root cause of inflammation, and bring new opportunities for the treatment of inflammation-related diseases. In the field of anti-tumor, it may interfere with the process of tumor cell proliferation, invasion and metastasis, acting as a strong barrier, inhibiting the raging of tumor cells, and bringing hope to cancer patients.
    Discussing the market prospects, with the increasing aging of the population and the increasing incidence of chronic diseases, there is a hunger for new and efficient therapeutic drugs. Due to its potential therapeutic effect, this compound is expected to be developed into an innovative drug and seize market share. Furthermore, the scientific research community is paying increasing attention to it, the research investment is increasing, and the research and development progress may change with each passing day, further expanding its market application scope.
    However, there are also challenges. The road to drug development is full of thorns. From laboratory research to clinical application, it needs to go through rigorous clinical trials to ensure its safety and effectiveness. And the market competition is fierce, many pharmaceutical companies and scientific research institutions are engaged in new drug research and development. If they want to stand out, they need to speed up the pace of research and development and improve product quality.
    Overall, 2-amino-5-oxo-7- (isopropyl) -5H-chromono [2,3-b] pyridine-3-carboxylic acid faces challenges, but its unique pharmacological activity and broad market demand make it have a bright market prospect, and it is expected to bloom in the pharmaceutical stage and contribute to human health and well-being.