2 Amino 5 Methyl 3 Pyridinecarboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-5-methyl-3-pyridinecarboxylic acid

    Specifications

    HS Code

    180958

    Name 2-Amino-5-methyl-3-pyridinecarboxylic acid
    Molecular Formula C7H8N2O2
    Molar Mass 152.15 g/mol
    Appearance Solid (presumably, common for such organic compounds)
    Physical State At Room Temp Solid
    Solubility In Water Moderate (estimated, based on polar groups)
    Pka For -COOH group around 3 - 5 (estimated for pyridine carboxylic acid)
    Color Colorless to white (typical for many amine - carboxylic acid compounds)

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    General Information
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    Frequently Asked Questions

    As a leading 2-Amino-5-methyl-3-pyridinecarboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-Amino-5-methyl-3-pyridinecarboxylic acid?
    2-Amino-5-methyl-3-pyridinecarboxylic acid, this is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, which is quite stable at room temperature and pressure.
    From the perspective of acidity and alkalinity, it is acidic because it contains carboxyl groups (-COOH). The carboxyl group can dissociate hydrogen ions (H 🥰) under suitable conditions, thus exhibiting acidic properties. It can neutralize and react with bases to generate corresponding salts and water.
    In terms of solubility, generally speaking, it is slightly soluble in water. This is due to the fact that although there are carboxyl groups in its molecular structure that can form hydrogen bonds with water, the pyridine ring and methyl group are hydrophobic groups, which limits its solubility in water. However, it is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc., which facilitates its application in organic synthesis reactions.
    When it comes to chemical reaction activity, both amino (-NH2O) and carboxyl groups are active functional groups. Amino groups are nucleophilic and can participate in many nucleophilic substitution reactions. For example, they react with acyl halides, acid anhydrides, etc., to form amide bonds. This reaction is widely used in the field of peptide synthesis and other fields. The carboxyl group can not only participate in the neutralization reaction, but also undergo esterification reaction under specific conditions, and form ester compounds with alcohols under acid catalysis. This reaction is often used in organic synthesis to prepare fragrances, pharmaceutical intermediates, etc.
    Furthermore, the pyridine ring endows the compound with certain aromaticity and stability. The nitrogen atom on the pyridine ring can participate in the coordination reaction to form complexes with metal ions. These complexes may have potential application value in catalysis, materials science and other fields. Due to its structural properties, 2-amino-5-methyl-3-pyridine carboxylic acid has attracted attention in many fields such as medicinal chemistry, materials science and organic synthesis chemistry, and is expected to become a key intermediate for the creation of new drugs and functional materials.
    What are the main uses of 2-Amino-5-methyl-3-pyridinecarboxylic acid?
    2-Amino-5-methyl-3-pyridinecarboxylic acid, this is an organic compound. It has a wide range of uses and is often a key intermediate in the field of medicine. Because its structure contains specific functional groups, it can be converted into biologically active molecules by organic synthesis, which can be used to create drugs for treating various diseases.
    In pesticides, it also has important uses. It can be chemically modified to produce pesticide active ingredients, which have inhibitory or killing effects on pests, pathogens, etc., and provide protection for agricultural harvests.
    In the field of materials science, this compound is also involved. Due to its special chemical properties, it may participate in the synthesis of materials with specific properties, such as optical materials, electrical materials, etc. With the reaction with other substances, the material is endowed with unique physical and chemical properties to meet the needs of different application scenarios.
    Furthermore, in chemical research, 2-amino-5-methyl-3-pyridinecarboxylic acid is used as a model compound to help researchers explore the organic reaction mechanism, clarify the reaction path and law, and contribute to the development of organic synthetic chemistry. In short, it plays an important role in many fields, promoting the progress and development of related fields.
    What are the synthetic methods of 2-Amino-5-methyl-3-pyridinecarboxylic acid?
    The synthesis method of 2-amino-5-methyl-3-pyridine carboxylic acid has been known for a long time, and this is a detailed description for you.
    First, pyridine derivatives are used as starting materials. First, take a suitable pyridine compound and introduce the methyl group in a delicate way under specific reaction conditions. This step requires the selection of appropriate reagents and catalysts, such as a specific halogenated methane, with a suitable base, under precise control of temperature and reaction time, the methyl group is cleverly connected to the fifth position of the pyridine ring. Then, the third position of the pyridine ring is carboxylated. Carboxyl groups can be successfully introduced through a series of complex and orderly reactions by means such as carbon dioxide and metal reagents. As for the formation of the 2-amino group, it can be achieved by aminolysis reaction or other related amination processes. In a suitable solvent and reaction environment, a specific nitrogen-containing reagent interacts with the pyridine derivative to obtain 2-amino-5-methyl-3-pyridine carboxylic acid.
    Second, there are also a series of exquisite transformations starting with other heterocyclic compounds through cyclization and rearrangement. First, a number of small molecule heterocyclic fragments are cyclized with ingenious reaction strategies to construct the prototype of the pyridine ring. In this process, the reaction conditions need to be precisely regulated to ensure the accuracy of the cyclization check point. Then, through a carefully designed rearrangement reaction, the position and structure of each substituent are ingeniously adjusted. During this period, the intermediate products of each step of the reaction need to be carefully separated and purified to prevent impurities from interfering with the subsequent reaction. After the structure of the pyridine ring tends to be ideal, methyl, carboxyl and amino groups are introduced in sequence. After multiple steps of delicate reaction, the final product 2-amino-5-methyl-3-pyridinecarboxylic acid is synthesized.
    The process of synthesis is like a craftsman carving beautiful jade, which requires careful step by step and careful control of the fineness of the reaction to obtain this good product.
    What is the price range of 2-Amino-5-methyl-3-pyridinecarboxylic acid in the market?
    Today I have a question, 2 - Amino - 5 - methyl - 3 - pyridinecarboxylic acid is in the market price range. This is a compound in the field of fine chemicals, and in order to know its price, it is necessary to study many ends.
    Looking at the past market conditions, its price often varies depending on the quality grade. For high purity, the process is complex and the cost is thick, and the price must be high; if the purity is slightly inferior, the price may be slightly lower. In addition, the manufacturer is also the key. Large factories are competitive due to scale effect and technical sophistication, cost or controllable; small factories are the opposite.
    Furthermore, the state of supply and demand also affects its price. If the demand is large, but the production is insufficient, the price will rise; if the supply exceeds the demand, the price may drop. And market fluctuations, raw material prices rise and fall, all have an impact.
    However, there is no exact data at present, and it is difficult to specify the specific price range. For details, you can consult the chemical product trading platform, suppliers, or refer to recent market survey reports to get more accurate prices.
    What are the storage conditions for 2-Amino-5-methyl-3-pyridinecarboxylic acid?
    2-Amino-5-methyl-3-pyridinecarboxylic acid, this property is a chemical agent and the like. It is essential for storage, and the first environment is dry. Moisture is easy to cause many chemical reactions and cause it to deteriorate, so it should be placed in a dry place, avoid shade, and must not be exposed to humid atmosphere.
    Furthermore, temperature is also critical. Excessive temperature may cause it to decompose or exacerbate its reaction; too low temperature may also affect its chemical stability. Generally speaking, the storage temperature should be controlled between 15 and 25 degrees Celsius, so that its chemical properties can be relatively stable.
    And keep away from fire sources and oxidants. Because of its certain chemical activity, it is easy to cause violent reactions when exposed to fire or oxidants, and even cause ignition and explosion, endangering safety. Where to store, clear warning signs should be set up to inform everyone of its potential danger.
    In addition, storage containers should not be ignored. Containers with good corrosion resistance and sealing should be selected. Cover due to the substance or reaction with some materials, the container is damaged, and then leaks, pollutes the environment and endangers people. A well-sealed container can prevent the intrusion of external moisture, oxygen, etc., prolonging its shelf life.
    In summary, proper storage of 2-amino-5-methyl-3-pyridinecarboxylic acid requires a dry, cool, temperature-appropriate place, away from sources of ignition and oxidants, and suitable storage containers to ensure its quality and safety.