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What are the main uses of 2-amino-5-cyanopyridine?
2-Amino-5-cyanopyridine is 2-amino-5-cyanopyridine, which has a wide range of uses.
In the field of medicinal chemistry, it is a key intermediate for the synthesis of many drugs. Due to the characteristics of amino and cyano groups in the molecular structure, it can build complex molecular structures with specific biological activities through various chemical reactions. For example, in the creation of anti-tumor drugs, 2-amino-5-cyanopyridine is used as the starting material, and other pharmacoactive groups can be introduced through multi-step reaction to develop new drugs with inhibitory effect on tumor cells; in the field of antibacterial drugs, it can also be derived based on its structure to synthesize compounds with antibacterial activity against specific pathogens.
In the field of materials science, 2-amino-5-cyanopyridine can participate in the preparation of functional materials. Because of its functional groups, it can react with other organic or inorganic components to prepare materials with specific optoelectronic properties. For example, in the research and development of organic Light Emitting Diode (OLED) materials, using their unique structure, through rational molecular design and synthesis, luminescent materials with specific luminescence wavelengths and high efficiency can be prepared, which contributes to the development of display technology.
In pesticide chemistry, it can be synthesized as an important intermediate for a variety of pesticides. With its structural characteristics, chemically modified pesticides can be obtained with efficient pest control and environmental friendliness, which is conducive to the effective prevention and control of pests and diseases in agricultural production.
What are 2-amino-5-cyanopyridine synthesis methods?
2-Amino-5-cyanopyridine is an important compound in organic synthesis. Its synthesis method has been studied in the past, and now it is the way for you.
One of the methods can be started from 2-aminopyridine. In terms of the chemical properties of the pyridine ring, the amino group at a specific position on the pyridine ring can lead to a specific reaction. 2-Amino-pyridine and suitable cyanide reagents, such as potassium cyanide, under suitable reaction conditions, such as in a specific solvent, with appropriate catalysts, temperature, pressure and other factors, so that the cyanide group replaces the hydrogen atom at a specific position on the pyridine ring, and then obtains 2-amino-5-cyanopyridine. However, in this process, the cyanide reagent is quite toxic, and the operation needs to be extremely cautious to prevent harm.
Another method can be started from pyridine derivatives containing suitable substituents. First, groups that can be converted into amino and cyano groups are introduced into the pyridine ring, and then a series of chemical reactions, such as substitution, oxidation, reduction, etc., are followed by a series of chemical reactions to gradually build the target molecule. For example, using a halogenated pyridine derivative as a raw material, a group that can be converted into an amino group is first introduced through a nucleophilic substitution reaction, and then a cyano group is introduced at another position through a suitable reaction. In this process, the reaction conditions of each step need to be carefully controlled to ensure the selectivity and yield of the reaction.
Another strategy is heterocyclic synthesis. While using a multi-step reaction to construct a pyridine ring, an amino group and a cyano group are introduced. This strategy requires in-depth understanding and mastery of heterocyclic synthesis chemistry, ingenious design of the reaction route, and coordination of each step of the reaction to efficiently synthesize 2-amino-5-cyanopyridine.
All synthesis methods have their own advantages and disadvantages. Or the difficulty of obtaining raw materials is different, or the severity of reaction conditions is different, or the yield is different. However, it is the exploration and practice in the field of organic synthetic chemistry to obtain this compound.
What are the physical properties of 2-amino-5-cyanopyridine?
2-Amino-5-cyanopyridine, Chinese name 2-amino-5-cyanopyridine, is a kind of organic compound. Its physical properties are as follows:
The appearance is mostly white to light yellow crystalline powder, which is easy to recognize by the naked eye. In practical applications, its purity can be preliminarily judged.
The melting point is between 162-165 ° C. The melting point is the inherent characteristic of the substance. This temperature range can be used as an important basis for the identification of the compound. In the separation and purification of the substance, the melting point can be used to determine whether the substance is pure.
The compound is slightly soluble in water, which indicates that the force between its molecules and water molecules is weak. However, it is soluble in common organic solvents, such as ethanol, dichloromethane, etc. In organic synthesis experiments, suitable solvents can be selected according to their solubility for reaction, recrystallization, etc. For example, ethanol is used as a solvent for recrystallization to improve product purity.
In addition, 2-amino-5-cyanopyridine has certain stability, but its structure may change under extreme conditions such as strong acid, strong base or high temperature. Knowing this stability characteristic, when storing and using the compound, it should avoid such extreme conditions to prevent its deterioration and ensure its effect and performance in practical applications.
What is the price of 2-amino-5-cyanopyridine in the market?
In the market, the price of 2-amino-5-cyanopyridine varies from time to time, and also varies according to the quality and source. In the past, the price of such chemical substances was often tied to the balance between supply and demand, and also related to the difficulty of production and the amount of production.
If in the past, if the production method of this product was complicated, and the production was scarce, and there were many people who needed it, its price would be high. However, if the production method is becoming more and more simple, the production is gradually increasing, and the demand is unchanged, or slightly reduced, the price should drop.
Looking at "Tiangong Kaiwu", although the price of 2-amino-5-cyanopyridine is not explicitly stated, it talks about all kinds of process products, including the difficulty of production and the consumption of materials. This is the same as the pricing of chemical products.
At present, if you want to know the exact price of 2-amino-5-cyanopyridine, you should consult various chemical material suppliers, or observe the market of chemical transactions, to get the current actual price. Given the ever-changing market conditions, it is difficult to have a fixed number, so it is difficult to judge the current price based on the old practice. Only by going through the intercity inquiry can you know the details.
What are 2-amino-5-cyanopyridine storage conditions?
2-Amino-5-cyanopyridine is an important compound in organic chemistry. Its storage conditions are related to the maintenance of its quality and the effectiveness of its use, which cannot be ignored.
This compound should be stored in a cool and dry place. Covering a cool environment can reduce the rate of chemical reactions caused by excessive temperature. If it is at high temperature, the molecular movement will intensify, or it will cause adverse reactions such as decomposition and polymerization, which will damage its chemical structure and purity. Dry environment is also key. 2-Amino-5-cyanopyridine encounters water vapor or undergoes reactions such as hydrolysis, resulting in impure products. If in a humid place, the cyano group may be hydrolyzed into a carboxyl group, causing its chemical properties to change greatly.
and should be stored in a well-ventilated place. Good ventilation can prevent the accumulation of volatile gases and reduce the risk of explosion and poisoning. Because its volatile gases are flammable or toxic, if accumulated in a limited space, it is easy to cause danger in case of open fire or static electricity.
Furthermore, when stored, it should be isolated from oxidants, acids and other substances. In the structure of 2-amino-5-cyanopyridine, both amino and cyano groups have certain reactivity. Oxidants are strongly oxidizing, or react with compounds containing amino groups to destroy their structures; acids may also react with amino groups to form salts, causing their chemical properties to change.
In addition, the choice of storage containers is also particular. It is advisable to use containers with good sealing performance, such as glass bottles or specific plastic bottles. Glass bottles are chemically stable and do not easily react with compounds; plastic bottles need to be chemically resistant to ensure that 2-amino-5-cyanopyridine is not disturbed by external factors during storage and maintains its inherent chemical properties and purity for subsequent experiments, production and other purposes.