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What is the main use of 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine
2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine, an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to help create various drug molecules with specific biological activities.
In the process of drug development, due to its unique chemical structure, it can be cleverly combined with other compounds through specific chemical reactions to build a molecular structure with complex structure and pharmacological activity. For example, its amino group can react with carboxyl groups, halogenated hydrocarbons, etc., to achieve the construction of carbon-nitrogen bonds to prepare new drugs. In the synthesis of some anti-cancer and anti-infective drugs, it is possible to use this as a starting material and carefully build target molecules through multi-step reactions.
In addition, in the field of organic synthetic chemistry, it is also an important cornerstone. It can be used to synthesize heterocyclic compounds with novel structures, opening up new directions for organic synthetic chemistry. Due to the unique physicochemical properties and biological activities of thiazolopyridine compounds, this compound offers synthetic chemists many possibilities to create organic materials and functional molecules with special properties. It plays an indispensable role in both organic synthesis and medicinal chemistry, injecting a steady stream of impetus into the development of related fields.
What are the synthesis methods of 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine
The synthesis method of 2-amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine is a key exploration in the field of organic synthesis. Its synthesis pathways are diverse, and here are several ends.
First, it can be obtained by the reaction of sulfur-containing compounds with nitrogen-containing heterocyclic precursors. First, take a suitable sulfur-containing raw material, such as thiols or thioethers, and a nitrogen-containing heterocyclic compound with appropriate activity, and under specific reaction conditions, make the two condensate. In the meantime, a suitable catalyst needs to be selected to help the reaction proceed smoothly. Such as some metal salts or organic base catalysts, the reaction rate and selectivity can be regulated. The temperature and time of the reaction also need to be carefully controlled to make the reaction evolve in the expected direction and form the prototype of the target product.
Second, the strategy of gradually constructing the ring system is adopted. The thiazole ring part is first synthesized, and the thiazole ring structure is constructed by the reaction of thioamide with halogenated hydrocarbons or carbonyl compounds. Subsequently, through suitable reaction conditions, the pyridine ring fragment is introduced to achieve the complete synthesis of 2-amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine. In this process, the intermediates in each step of the reaction need to be properly separated and purified to ensure the purity of the final product.
In addition, a protective group strategy can also be considered. For easily reactive groups in the molecule, such as amino groups, protective groups such as Cbz are used to protect them from unnecessary side reactions during the reaction process. After the main structure is constructed, the amino groups are reactivated through a mild deprotection reaction to achieve the synthesis of the target product. All steps need to follow the principles and laws of organic synthesis, and careful operation can achieve the desired synthetic effect.
What are the physicochemical properties of 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine
2-Amino-5-benzyloxycarbonyl-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine, which is an organic compound. Its physical and chemical properties are unique and of great research value.
Looking at its physical properties, under normal temperature and pressure, it is mostly in solid form, and the structure is maintained due to the relatively stable intermolecular forces. In terms of melting point, it will vary depending on the compactness of the molecular structure, but the specific value needs to be determined by accurate experiments.
As for solubility, due to the existence of polar groups in the molecule, such as amino groups and nitrogen-sulfur atoms on thiazole rings, which can interact with polar solvents to form hydrogen bonds, etc., it may have a certain solubility in polar solvents such as water and alcohols; while benzyloxycarbonyl is a non-polar group, it also has a certain solubility in non-polar organic solvents such as alkanes.
When it comes to chemical properties, amino groups have significant activity and are easy to participate in nucleophilic reactions, such as reactions with acyl chloride and acid anhydride, etc., to form corresponding amide derivatives. Benzyloxycarbonyl can undergo deprotection reactions under specific conditions, releasing amino groups and expanding the reaction path of compounds. As the core structure, thiazolopyridine ring has both aromatic and basic properties, and can react with acids to form salt compounds. In addition, due to the existence of unsaturated bonds and heteroatoms, the compound can participate in various cyclization, addition and other reactions, showing rich chemical reactivity and broad application prospects in the field of organic synthesis.
What is the price range of 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine in the market?
I don't know what the market price of 2 - Amino - 5 - Cbz - 4,5,6,7 - tetrahydro - 1,3 - thiazolo [5,4 - c] pyridine is. This is a rather professional chemical substance, and its price fluctuates greatly and is often influenced by many factors.
First, purity is crucial. If the purity is very high, it is suitable for high-end scientific research or special industrial use, and the price is high; if the purity is slightly lower, it is only for general experimental or basic applications, and the price is relatively easy.
Second, the supply and demand situation has a deep impact. If the market demand is strong and the supply is limited, if there is a surge in demand for it in a specific industry, the production scale will be difficult to expand for a while, and the price will rise; on the contrary, if the demand is low and the supply is sufficient, the price may decline.
Third, the difficulty of production also plays a role. If the synthesis steps are complicated, rare raw materials or special processes are required, the cost will be high, and the price will also rise; if the synthesis is relatively simple and the cost is controllable, the price may be in a lower range.
Fourth, the market competition situation should not be underestimated. If multiple manufacturers produce this product, the competition is fierce, and the price may become reasonable in order to compete for market share; if the market is almost monopolized, the manufacturer's pricing power is strong, and the price may remain high.
And the market price changes from time to time, it is difficult to give the exact price range. For details, you can consult chemical product suppliers, reagent sales platforms, or inquire about the market at relevant professional forums and industry exhibitions to get a more accurate price.
What are the storage conditions for 2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine?
2-Amino-5-Cbz-4,5,6,7-tetrahydro-1,3-thiazolo [5,4-c] pyridine is a precious organic compound whose storage conditions are crucial to its quality and stability. This compound should be stored in a low temperature, dry and dark place.
Low temperature environment can greatly slow down the thermal movement of compound molecules, thereby reducing the rate of chemical reactions, effectively avoiding decomposition or deterioration due to excessive temperature. Generally speaking, it is more suitable to store it in the refrigerated layer of the refrigerator at a temperature between 2 and 8 degrees Celsius.
Dry conditions are also indispensable. The moisture in the air can easily interact with the compound, or cause adverse reactions such as hydrolysis, which can damage its chemical structure and properties. Therefore, when storing, be sure to ensure that the storage container is well sealed. Consider adding desiccants, such as anhydrous calcium chloride, silica gel, etc., to absorb water vapor that may invade and maintain a dry storage environment.
Avoidance from light is also important. Light, especially ultraviolet rays, have high energy, or can trigger photochemical reactions of compounds, causing their structure to change. Therefore, it should be stored in a dark container such as a brown bottle, and placed in a dark place to avoid light. < Br >
Proper storage of this compound, following the principles of low temperature, drying, and protection from light, can effectively maintain the stability of its chemical properties and ensure its effective use in subsequent scientific research, production, and other applications.