2-Amino-5-carbamoylpyridine

2-Amino-5-formamidopyridine has a wide range of uses. In the field of medicine and chemical industry, it is a key intermediate for the synthesis of many drugs. The unique structure of the gainpyridine ring with amino and formamido groups endows it with various reactivity, and it can construct complex drug molecular structures through various chemical reactions.
For example, in the synthesis of antibacterial drugs, 2-amino-5-formamidopyridine can be spliced with other compounds through specific reaction steps to prepare drugs that have inhibitory or killing effects on specific bacteria. Furthermore, in the field of materials science, it may be used to prepare functional materials. With its own structural characteristics, it participates in the material synthesis process, endows materials with special properties such as optics and electricity, such as the preparation of organic optoelectronic materials, and provides new ways for material performance optimization.
And in the field of organic synthetic chemistry, it is often used as a building block for organic synthesis. Because of its rich activity check points, it can trigger various reactions such as nucleophilic substitution and electrophilic substitution, which help organic chemists construct various organic compounds, greatly promote the development of organic synthetic chemistry, and lay the foundation for the creation and performance research of new compounds.

2-Amino-5-formamidopyridine is an important compound in the field of organic chemistry. Its physical properties are particularly critical and are exhibited in many chemical processes and applications.
First of all, under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This form is easy to store and operate, and in many chemical reactions, the powder form can promote the reaction to proceed more smoothly, because it has a large specific surface area and is more fully in contact with other reactants.
The melting point of 2-amino-5-formamidopyridine is about 190-195 ° C. Melting point is an inherent physical property of a substance, which is of great significance for the determination of its purity and thermal stability. If the compound has high purity, its melting point range will be relatively narrow; if it contains impurities, the melting point may be reduced and the melting range lengthened. This melting point characteristic also determines its state transition during heating. When setting specific reaction conditions, this melting point factor needs to be fully considered to ensure that the reaction occurs within a suitable temperature range.
Furthermore, 2-amino-5-formamido pyridine is slightly soluble in water. This solubility characteristic is closely related to its molecular structure, which contains both hydrophilic amino and formamido groups, as well as hydrophobic pyridine rings. This structure makes it limited in solubility in water. However, in some organic solvents such as ethanol and dichloromethane, its solubility is relatively good. This difference in solubility provides an important basis for the separation, purification and solvent selection of compounds. Chemists can choose suitable solvents based on their solubility to achieve efficient separation and purification of compounds, or to create an environment conducive to specific reactions.
In summary, the physical properties of 2-amino-5-formamido pyridine, such as appearance, melting point, solubility, etc., play an indispensable role in many fields such as organic synthesis and pharmaceutical chemistry, laying a solid foundation for related research and applications.

The synthesis method of 2-amino-5-formamido-pyridine has been known for a long time. To obtain this compound, there are three common ways.
First, pyridine is used as the starting material. The formyl group is introduced at a specific position of the pyridine first, and the appropriate reagent and reaction conditions are selected in this step. After formylation, the amination reaction is carried out. During amination, an ammonia source and a suitable catalyst are selected, and the target molecular structure is gradually constructed through multi-step conversion. Although this approach is complicated, the reaction conditions are properly controlled, and high yields can be obtained.
Second, pyridine derivatives are used as the starting materials. If there are some pyridine derivatives containing suitable substituents, they can be gradually converted into 2-amino-5-formamido pyridine by modifying the substituents. For example, some halogen-containing pyridine derivatives can be synthesized by nucleophilic substitution reaction, replacing halogens with amino and formamido groups. The key to this approach lies in the selection of the starting pyridine derivatives and the optimization of subsequent reaction conditions.
Third, by means of heterocyclic synthesis. Using nitrogen-containing and carbon-containing small molecules as raw materials, pyridine rings are constructed by cyclization reaction, and amino and formamido groups are introduced into the rings at the same time. This approach requires careful design of the reaction route, rational selection of reaction reagents and catalysts, so that each step of the reaction can be coordinated to achieve the purpose of synthesis.
The synthesis process requires attention to the precise regulation of reaction conditions, such as temperature, pH, reaction time, etc. Only when all conditions are suitable can the yield and product purity be improved, resulting in the synthesis of 2-amino-5-formamidopyridine.

The price range of 2-amino-5-formamido-pyridine in the market is what you are inquiring about. Sadly, the market price is changing, and it is affected by many factors, such as the amount of raw materials, the situation of supply and demand, the difficulty of process, regional differences, and different manufacturers.
In the past market, the price of raw materials either fell due to the rise in the price of raw materials, or rose due to the strong demand. And the price of 2-amino-5-formamido-pyridine of different qualities and specifications varies greatly. If its purity is extremely high, it is suitable for high-end fine chemical fields, and the price is high; while the purity is slightly lower, for ordinary industrial purposes, the price may be slightly lower.
Furthermore, different regions have different transportation costs, tax policies, etc., which will also lead to different prices. In places where the chemical industry gathers, due to abundant supply and intense competition, the price may tend to be flat; in remote places, due to the superposition of transportation and other costs, the price may be slightly higher.
However, it is difficult for me to determine the specific price range. If you want to know the exact price, you should consult chemical raw material suppliers, traders, or professional chemical trading platforms and information websites to get close to the current market price range.

2-Amino-5-formamidopyridine is an important chemical substance, which is used in many fields such as chemical industry and medicine. However, it has certain latent risks, and many safety precautions should be paid attention to when using it.
First of all, it is related to the toxicity of this substance. It may cause harm to the human body. If inadvertently exposed, it may cause skin and eye irritation, inhalation or ingestion or damage to the respiratory tract, gastrointestinal tract, etc. Therefore, when operating, be sure to take good protection, wear protective clothing, gloves and goggles, work in a well-ventilated place, and avoid inhaling dust or steam.
Secondly, its chemical properties also need attention. 2-Amino-5-formamidopyridine or flammable, should be kept away from fire and heat sources, properly stored, and not co-stored with strong oxidants to prevent dangerous reactions.
In addition, there are many points to pay attention to during use and disposal. After the experimental operation, the equipment should be properly cleaned to prevent residual substances from causing pollution. If there is any waste, it needs to be disposed of in accordance with relevant regulations, and it must not be discarded at will to avoid damage to the environment.
In addition, the staff needs to be professionally trained to be familiar with its characteristics, safety operating procedures and emergency treatment methods. In the event of an accident, such as contact with skin or eyes, rinse with plenty of water immediately and seek medical attention in a timely manner; if inhaled or ingested, move to a fresh air place as soon as possible, perform first aid measures such as artificial respiration if necessary, and send to medical attention promptly.
In short, when using 2-amino-5-formamide pyridine, it is necessary to fully understand its characteristics, strictly follow safety procedures, and make protective and emergency preparations to ensure that personnel safety and the environment are not damaged.