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What is the chemistry of 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile?
2-Amino-5-bromo-4-methylpyridine-3-formonitrile, this is an organic compound with specific chemical properties.
In terms of physical properties, it is mostly solid under normal conditions. Due to the presence of polar groups, it may have certain solubility in specific organic solvents. For example, in common organic solvents such as ethanol and dichloromethane, or depending on the interaction between molecules, it shows different dissolution conditions.
In terms of chemical properties, amino groups (-NH2O) are basic and can react with acids to form corresponding salts. Under suitable conditions, it can participate in nucleophilic substitution reactions because the nitrogen atom in the amino group has lone pair electrons and is nucleophilic. 5-Bromo atoms are active check points and prone to substitution reactions. In many organic reactions, bromine atoms can be replaced by other groups. For example, under the action of nucleophiles, bromine ions leave and other nucleophilic groups connect. Although 4-methyl (-CH 🥰) is relatively stable, it may be oxidized under specific strong oxidation conditions. The 3-formonitrile (-CN) group can participate in a variety of reactions, such as hydrolysis reactions that can generate carboxyl groups (-COOH), or react with nucleophiles to realize the construction of carbon-carbon bonds, which is of great significance in the field of organic synthesis. It can be converted into other functional groups through various reaction paths, laying the foundation for the synthesis of complex organic molecules.
What are the main uses of 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile?
2-Amino-5-bromo-4-methylpyridine-3-formonitrile is a crucial compound in the field of organic synthesis. It has a wide range of uses and plays a key role in many fields.
Bearing the brunt, in the field of pharmaceutical chemistry, this compound is often used as a key intermediate. Due to the existence of specific functional groups such as pyridine ring and cyano, amino and halogen atoms, it has unique chemical and pharmacological activities. With its structural modification and modification, researchers can synthesize a series of derivatives with potential biological activities, such as the development of antibacterial, anti-inflammatory, anti-tumor and other drugs. Taking the development of a new type of antibacterial drug as an example, chemists have successfully obtained compounds that exhibit high inhibitory activity against specific drug-resistant bacteria by modifying the structure of 2-amino-5-bromo-4-methylpyridine-3-formonitrile, opening up new avenues for the development of antibacterial drugs.
Furthermore, in the field of materials science, 2-amino-5-bromo-4-methylpyridine-3-formonitrile also has application potential. Because of its functional groups, it can participate in specific chemical reactions to build functional materials. For example, materials with special optical, electrical or magnetic properties can be prepared by polymerization or compounding with other organic and inorganic materials, and may have outstanding performance in photoelectric materials, sensor materials, etc.
In addition, in organic synthetic chemistry, this compound is often the cornerstone of building complex organic molecules. Because of its rich functional groups, it can participate in a variety of classical organic reactions, such as nucleophilic substitution, electrophilic substitution, coupling reactions, etc. Chemists can use these reactions to gradually build complex organic compounds, providing powerful tools for the total synthesis of natural products and the creation of new organic functional molecules.
In summary, 2-amino-5-bromo-4-methylpyridine-3-formonitrile occupies an important position in many fields such as drug research and development, material preparation and organic synthesis due to its unique structure and chemical activity, and is of great significance for promoting scientific research and technological development in related fields.
What are 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile synthesis methods?
The method for preparing 2-amino-5-bromo-4-methylpyridine-3-formonitrile has several common paths.
First, the starting material containing the pyridine structure can be started. First, find a pyridine derivative with a suitable substituent, such as 4-methylpyridine-3-formonitrile, and introduce a bromine atom at its 5-position through a bromination reaction. This bromination reaction is usually carried out in the presence of light or an initiator in a suitable solvent, such as dichloromethane and carbon tetrachloride. After the bromination is completed, the amination reaction is carried out. Ammonia, amine reagents or other amination reagents can be used to replace bromine atoms with amino groups under suitable temperature, pressure and catalyst conditions, so as to obtain the target product 2-amino-5-bromo-4-methylpyridine-3-formonitrile.
Second, the strategy of constructing pyridine rings can also be used. Suitable small molecule compounds, such as β-dicarbonyl compounds, nitriles and nitrogen-containing compounds, are used to construct pyridine rings through multi-step reactions. Pyridine skeletons are first formed by condensation, cyclization and other reactions, and then methyl, bromine atoms and amino groups are introduced in sequence. In this process, the conditions of each step of the reaction need to be finely regulated, such as temperature, pH, reaction time, etc., to ensure that the reaction proceeds in the desired direction and the final product is obtained.
Third, you can also refer to the synthesis methods of similar compounds to optimize the reaction conditions, reagents, etc. Or choose a specific catalyst in the reaction to improve the selectivity and yield of the reaction. In the post-treatment stage of the reaction, suitable separation and purification methods, such as column chromatography, recrystallization, etc., are also required to obtain high-purity 2-amino-5-bromo-4-methylpyridine-3-formonitrile.
2-Amino-5-bromo-4-methylpyridine-3-carbonitrile need to pay attention to when storing
2-Amino-5-bromo-4-methylpyridine-3-formonitrile is an important chemical substance, and many aspects need to be paid attention to when storing.
Bear the brunt, and the temperature and humidity of the storage environment are crucial. This substance should be stored in a cool and dry place to prevent its chemical properties from changing due to excessive temperature, or deliquescence due to excessive humidity. Excessive temperature may cause molecular movement to intensify, resulting in damage to its stability; while humid environment may cause the substance to absorb water, affecting purity and quality.
Furthermore, attention should be paid to the ventilation of the storage place. Good ventilation can avoid potential dangers caused by local gas accumulation. If the substance volatilizes to produce certain gases, poor ventilation or increase the gas concentration, or there is a risk of explosion, poisoning, etc.
The choice of storage containers should not be ignored. Suitable containers should be selected, which must be able to effectively prevent material leakage, and the material should not chemically react with 2-amino-5-bromo-4-methylpyridine-3-formonitrile. For example, glass containers may be suitable in some cases, but if the substance has a corrosive effect on the glass, special materials should be selected.
In addition, care should be taken to avoid mixing with other chemical substances. 2-Amino-5-bromo-4-methylpyridine-3-formonitrile may react chemically with certain substances, resulting in deterioration or dangerous products. Therefore, when storing, it is necessary to ensure that it is stored separately, or stored in partitions with substances that are known not to react.
It is also necessary to set up a clear label on the storage area, marking the name, characteristics, danger warning and other information of the substance. In this way, the staff can quickly know its nature and take appropriate protective measures during operation to ensure the safety of personnel and the integrity of the substance.
In conclusion, proper storage of 2-amino-5-bromo-4-methylpyridine-3-formonitrile requires careful consideration from various aspects such as temperature and humidity, ventilation, containers, mixing, and labeling to ensure its quality and safety.
What is the market price of 2-Amino-5-bromo-4-methylpyridine-3-carbonitrile?
We are inquiring about the market price of 2-amino-5-bromo-4-methylpyridine-3-formonitrile. However, the price of this chemical is difficult to determine, and it is affected by many factors.
First, the price of raw materials has a great influence. If the price of various raw materials required for its synthesis fluctuates due to changes in time, place of origin, and supply and demand, the price of 2-amino-5-bromo-4-methylpyridine-3-formonitrile will also change accordingly.
Second, the method of preparation is also related to the price. If there is an efficient and simple method, the cost can be reduced, and the price may be lower; on the contrary, if the preparation is cumbersome and costly, the price will be high.
Third, market supply and demand are particularly critical. If there are many seekers and few suppliers, the price will rise; if there is an oversupply, the price will fall.
Fourth, the difference between manufacturers also contributes to the price difference. Products from famous factories may be higher than other factories due to their excellent quality and good information.
In summary, if you want to determine the market price, you should search for information widely and consult the chemical market and manufacturers to obtain a near-real price. Although it is difficult to determine the exact number, it may be possible to determine the approximate price.