2-Amino-5-bromo-3-nitropyridine

2-Amino-5-bromo-3-nitropyridine is very important in the field of organic synthesis. It is often used as a key intermediate to create a variety of medicines, pesticides and functional materials.
In pharmaceutical synthesis, with its unique chemical structure, specific functional groups can be introduced through a series of reactions, and then the molecular structure with biological activity can be constructed. For example, in the synthesis of some antibacterial and antiviral drugs, 2-amino-5-bromo-3-nitropyridine is often used as the starting material, and the core part of the efficacy is built through precise reaction manipulation.
In the field of pesticides, it can be an important building block for the synthesis of high-efficiency and low-toxicity pesticides. By ingeniously combining with other chemical components, pesticides are endowed with unique insecticidal, bactericidal or weeding properties, which can help agricultural yield and plant protection.
In the preparation of functional materials, it can use its activity check point to participate in polymerization reactions or modification processes to make the materials have special electrical, optical or adsorption properties, such as the application of new photoelectric materials, the creation of adsorption and separation materials, etc. In short, 2-amino-5-bromo-3-nitropyridine plays an indispensable role in many chemical-related industries and plays a significant role in promoting the development of related fields.

Pyridine is often used as the starting material for the synthesis of 2-amino-5-bromo-3-nitropyridine. After the bromination reaction of pyridine, bromine atoms can be precisely introduced into the specific position of the pyridine ring. In this step, a suitable brominating reagent, such as liquid bromine, is selected with a suitable catalyst, and bromine-containing pyridine derivatives are obtained at the appropriate temperature and reaction time.
Then, the bromine-containing pyridine derivatives are nitrified. During the nitrification process, it is necessary to control the reaction conditions and select the mixed acid system of nitric acid and sulfuric acid as the nitrifying reagent. Due to the strong nitrification ability of mixed acids, nitro groups can be introduced into the predetermined position. Through precise regulation of temperature, reagent ratio and other factors, the nitro group selectively falls on the specific check point of the pyridine ring to achieve the preparation of 5-bromo-3-nitropyridine.
Finally, the amination reaction of 5-bromo-3-nitropyridine is carried out. Generally, ammonia is used to react with 5-bromo-3-nitropyridine in the presence of suitable solvents and catalysts. After a series of processes such as nucleophilic substitution, the bromine atom is replaced by an amino group, and 2-amino-5-bromo-3-nitropyridine is successfully prepared. Each step of the reaction requires careful regulation of the reaction conditions, including temperature, pH, reaction time, etc., to ensure the smooth progress of each step of the reaction, in order to enhance the yield and purity of the target product.

2-Amino-5-bromo-3-nitropyridine, this is an organic compound. Its physical properties are quite important and are related to many practical applications.
Looking at its appearance, it often shows a yellow to brown crystalline powder shape, which is crucial for identification and preliminary judgment. Such colors and shapes are its distinctive appearance markers, which can provide an intuitive basis for experimenters or researchers to initially identify.
When it comes to solubility, 2-amino-5-bromo-3-nitropyridine has a certain solubility in organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF). However, in water, its solubility is relatively small. This difference in solubility is due to the characteristics of amino groups, bromine atoms and nitro groups contained in its molecular structure. The molecular structure and polarity of organic solvents interact with the compound, so that it can be well dispersed and dissolved in it; while the polarity of water is strong, but it interacts with the compound in a different way, resulting in limited solubility in water. This solubility is of great significance for the selection of solvents in chemical reactions. Suitable solvents can promote the reaction and improve the reaction efficiency and yield.
In terms of melting point, it is about 190-194 ° C. The melting point is the inherent physical property of the substance, which is like the "ID card" of the compound. Accurate melting point data can help determine its purity. If the actual measured melting point deviates too much from the known value, or implies that the compound contains impurities. And the melting point plays an extraordinary role in the separation, purification and identification process of compounds, and the appropriate separation and purification method can be selected accordingly.
Furthermore, 2-amino-5-bromo-3-nitropyridine has certain stability, but under certain conditions, chemical reactions can also occur. The bromine atom in its molecule is active and can participate in the nucleophilic substitution reaction; the nitro group has strong electron absorption, which affects the distribution of the electron cloud of the pyridine ring, enhances the amino acid property, and can also participate in a variety of reactions. Understanding this stability and reactivity is crucial for designing relevant chemical reaction routes and controlling reaction conditions, so as to avoid the decomposition of compounds or the uncontrolled reaction due to improper conditions.

2-Amino-5-bromo-3-nitropyridine is also an organic compound. It has many chemical properties and is worthy of careful investigation.
In terms of its acidity and alkalinity, the intramolecular amino group (\ (- NH_ {2}\)) is weakly basic and can react with acids to form corresponding salts. This is because the nitrogen atom in the amino group contains lone pairs of electrons and can accept protons. However, the existence of the pyridine ring has a certain effect on the alkalinity of the amino group, making it slightly less basic than the fatty amines.
Its halogenation properties are also significant, and the activity of the 5-position bromine atom is quite high. Under suitable conditions, nucleophilic substitution reactions can occur. For example, when reacting with nucleophiles such as alkoxides and amines, bromine atoms can be replaced by corresponding groups, resulting in the generation of many new compounds. This reaction mechanism is usually that nucleophiles attack the carbon atoms connected to bromine atoms, and bromine ions leave to complete the substitution process. The presence of
nitro (\ (- NO_ {2}\)) endows the molecule with strong electron absorption. This not only affects the electron cloud distribution of the molecule, but also reduces the electron cloud density of the pyridine ring, which in turn affects the reactivity of other groups on the ring; and nitro groups can participate in the reduction reaction. Under the action of appropriate reducing agents, nitro groups can be gradually reduced to different reduced products such as amino groups and hydroxylamines, which is an important conversion step in organic synthesis, which can be used to introduce more functional groups and expand the uses of compounds.
In addition, 2-amino-5-bromo-3-nitropyridine has a wide range of uses in the field of organic synthesis because it contains multiple active groups. It can be used as a key intermediate for the construction of more complex heterocyclic compounds, with potential application value in many fields such as pharmaceutical chemistry and materials science.

I look at your question about the market price range of "2 - Amino - 5 - bromo - 3 - nitropyridine", which is a question in the field of fine chemicals. However, the market price often changes from time to time and is also influenced by many factors. It is difficult to determine the exact price range.
Looking at past market conditions, the price of this compound may vary depending on purity, supply and demand conditions, production processes, etc. If its purity is quite high, the preparation process is complicated, and the market demand is strong, its price may be high. On the contrary, if it is easy to prepare and the supply is sufficient, the price will drop slightly.
According to past experience, if the purity is about 95%, the price per gram may range from tens of yuan to 100 yuan. If the purity rises to 98% and above, the price may rise sharply, reaching hundreds of yuan per gram. However, this is only speculation. The current market is changing, raw material price fluctuations, policy implications, etc., can cause prices to fluctuate. To know the exact price, consult chemical raw material suppliers and chemical trading platforms to get real-time prices.