2 Amino 5 Bromo 3 Hydroxypyridine
pyridine pyrrole pyrazine piperidine piperazine

2-amino-5-bromo-3-hydroxypyridine

    Specifications

    HS Code

    650907

    Chemical Formula C5H5BrN2O
    Molecular Weight 189.01
    Appearance Solid (usually white to off - white powder)
    Melting Point Typically in a certain range (needs experimental determination)
    Boiling Point Estimated based on similar compounds
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Pka Value Relevant to its acidic - basic properties (needs experimental determination)
    Density Estimated value based on structure
    Stability Stable under normal conditions but may react with strong oxidizing or reducing agents
    Flash Point Estimated value related to its flammability

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    General Information
    Where to Buy 2-amino-5-bromo-3-hydroxypyridine in China?
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    Frequently Asked Questions

    As a leading 2-amino-5-bromo-3-hydroxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-amino-5-bromo-3-hydroxypyridine?
    2-% amino-5-bromo-3-furanylpyridine, although this substance is not directly mentioned in "Tiangong Kaiwu", it must be useful from the perspective of ancient chemistry, pharmacy and technology.
    In the process of pharmaceuticals, it may be a key medicinal reference. Ancient pharmaceuticals often seek precise proportions and unique formulas. This compound has a unique structure, or it can be used to adjust medicinal properties and enhance medicinal effects. For example, ancient elixir recipes are often combined with rare minerals, plants and trees, and by virtue of their special chemical properties, they can refine medicines for healing and saving people. If 2-% amino-5-bromo-3-furanylpyridine is added into the formula, it may change the intermolecular action of the drug, making the drug effect more specialized and fierce, and treating sinking diseases.
    In the art of dyeing and weaving, it may also be a dyeing aid. Ancient dyeing and weaving, the pursuit of bright and lasting color. This compound contains specific functional groups, or can be combined with fabric fibers to help dyes adhere better. In ancient times, dyeers made good use of various natural dyes, but the dyeing fastness was often insufficient. If this material is obtained, it may be able to make the dyed cloth last for years and washed with water, adding color to the dyeing and weaving industry.
    In the auxiliary link of metallurgy, it may have a wonderful effect. Ancient metallurgy, to improve purity and toughness. This compound may react with impurities in smelting to make the metal purer. For example, when smelting bronze, impurities affect the texture. 2-% amino-5-bromo-3-furanylpyridine can be cleverly removed to make bronze products more beautiful, durable, and improve metallurgical quality.
    What are the synthesis methods of 2-amino-5-bromo-3-hydroxypyridine?
    To prepare 2-amino-5-bromo-3-fluorobenzoic acid, there are many methods, each with its own advantages and disadvantages, and varies depending on the required raw materials, equipment and processes. The following common methods are briefly described:
    First, benzoic acid is used as the starting material. The benzoic acid is first brominated, and under suitable conditions, the bromine atom is substituted for the hydrogen at a specific position of the benzene ring to obtain a bromobenzoic acid derivative. After nitration, the nitro group is precisely introduced. This step requires careful control of the reaction conditions to prevent side reactions. Then the nitro group is reduced to an amino group. Common reducing agents include iron filings, hydrogen, etc. Finally, fluorine atoms are introduced. This process often requires special reagents and reaction conditions, such as the use of fluorine-containing reagents to react in appropriate solvents, and the target product is obtained through multi-step reactions.
    Second, starting from benzene. First, benzene is brominated and nitrified to construct a benzene ring structure containing bromine and nitro groups. Then, through the Fu-gram reaction, a carboxyl group is introduced to form a compound containing carboxyl groups, bromine and nitro groups. Then, the nitro group is reduced to an amino group as before, and finally fluorine atoms are introduced to synthesize the target molecule through a series of reactions.
    Third, benzene derivatives containing suitable substituents can be found as starting materials. If a compound with some target substituents on the benzene ring is found, the target product can be obtained by introducing the remaining required groups or converting the existing groups through a suitable reaction. This approach may reduce the reaction steps and increase the yield.
    When synthesizing this compound, attention should be paid to the control of the reaction conditions at each step, such as temperature, pH, reaction time, etc., which have a great impact on the reaction process and product purity. And different synthesis methods have different raw material costs, ease of operation and environmental impact. In practical application, it is necessary to comprehensively consider and choose the most suitable method.
    What is the market price of 2-amino-5-bromo-3-hydroxypyridine?
    Today there are 2-amino-5-bromo-3-fluoropyridine, what is the market price? The price of various items in the market often varies due to the quality, the amount of supply, and the urgency of demand. This 2-amino-5-bromo-3-fluoropyridine, if the quality is pure and the quantity is sufficient, and there are many people in the market, and the supply is rare, the price will be high; on the contrary, if the quality is defective and the supply is excessive, the price will be low.
    The price of all kinds of chemical products often varies depending on the difficulty of making them. If the preparation of 2-amino-5-bromo-3-fluoropyridine requires a lot of effort, and rare materials are used, its price should be high. If it is difficult to build, it will not be easy to obtain, and what is rare is expensive.
    Also, its price is also related to the place where the seller is. In Dayi, the capital of Tongdu, the business gathers the stock, the competition is fierce, and the price may be slightly flat; in remote places, the business is small and the goods are scarce, and every time the seeker suffers, the price may be high.
    However, I have not personally visited the market and examined the situation in detail, so it is difficult to determine the price of 2-amino-5-bromo-3-fluoropyridine. For details, you can consult pharmaceutical stores, chemical merchants, or visit the websites of Zhuyi to compare the prices of various companies and the approximate value, so that you can get a more accurate number.
    What are the physical and chemical properties of 2-amino-5-bromo-3-hydroxypyridine?
    2-% hydroxy-5-sulfonic acid-3-aminopyridine, this material is complex and has multiple characteristics.
    It has the properties of acid and base. Because it contains hydroxyl groups, it can weakly ionize hydrogen ions, which is acidic; amino groups have the ability to accept protons and are alkaline. In different acid-base environments, the ionization state will change, affecting its solubility and reactivity. In acidic media, amino groups are easily protonated, making the whole molecule positively charged; in alkaline environments, hydroxyl groups may deprotonate, making the molecule negatively charged.
    The solubility is quite special. There is a sulfonic acid group in the molecule, which is a strong hydrophilic group, so that the compound has a certain solubility in water; however, the pyridine ring and other groups have a certain hydrophobicity, so its solubility is not very high. And temperature, pH, etc. have a great influence on its solubility. If you heat up or change the pH to a suitable range, the solubility may be significantly improved.
    Chemical activity is quite rich. Amino groups can participate in many reactions, such as reacting with acyl halides and acid anhydrides to form amides, condensation reactions with aldose and ketone, etc. Hydroxyl groups can be esterified and etherified, and sulfonic acid groups can be substituted. Pyridine rings, as electron-rich aromatic rings, can undergo electrophilic substitution reactions, and the reaction check point is affected by other substituent localization effects. Under suitable conditions, halogen atoms, nitro groups and other groups can be introduced into the pyridine ring.
    Thermal stability also has characteristics. It is relatively stable in a certain temperature range, but if the temperature is too high, some chemical bonds in the molecule may break, triggering decomposition reactions. Under different conditions, decomposition products vary, or due to different chemical bond breaking methods and subsequent reactions.
    What are the precautions for storing and transporting 2-amino-5-bromo-3-hydroxypyridine?
    2-%E6%B0%A8%E5%9F%BA-5-%E6%BA%B4-3-%E7%BE%9F%E5%9F%BA%E5%90%A1%E5%95%B6%E7%B1%BB%E5%9E%8B%E7%9A%84%E5%82%A8%E5%AD%98%E4%B8%8E%E8%BF%90%E8%BE%93%E6%97%B6%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9:
    ###1. Storage
    1. ** Environment suitable **: This compound should be stored in a cool, dry and well-ventilated place. Due to its relatively active chemical properties, high temperature and humid environment are prone to deterioration. If it reacts with water vapor, it will change its chemical structure and affect the use efficiency.
    2. ** Container selection **: Corrosion-resistant containers should be selected. 2-Amino-5-bromo-3-fluoropyridine may chemically react with some metals or materials, so glass or specific plastic containers are more suitable, which can effectively avoid the interaction between containers and compounds and ensure its purity.
    3. ** Clear logo **: When storing, be sure to mark the compound name, specification, storage date and other key information in a prominent position in the container. This is not only easy to access, but also in case of problems, it can be traced back according to the logo to ensure the safety and effect of use.
    ###II. Transportation
    1. ** Tight packaging **: Make sure that the packaging is strong and well sealed before transportation. Because the compound may leak during bumps and collisions, which may cause danger, such as oxidation in contact with air after leakage, or reaction with surrounding substances, the packaging must be able to withstand certain external impact.
    2. ** Classified transportation **: According to its chemical properties, it is classified as the corresponding dangerous chemical category for transportation. The transportation process strictly follows relevant regulations and standards, and is equipped with necessary protective equipment and emergency treatment measures to prevent accidents during transportation and respond in a timely manner.
    3. ** Temperature control **: In some cases, temperature control is required during transportation. Extreme temperatures may affect the stability of compounds, so refrigerated or insulated transportation may be required to ensure the chemical stability of the transportation process.