2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine

2-Amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboran-2-yl) pyridine, this compound has many unique chemical properties. Its structure contains a pyridine ring, which is a six-membered nitrogen-containing heterocycle and is stable in nature. Due to the existence of nitrogen atoms, it has certain basicity and can react with acids to form salts. The 5-position boroester group, that is, 4, 4, 5, 5-tetramethyl-1, 3, 2-dioxyboroamyl-2-group, makes the compound have the characteristics of boron compounds. In organic synthesis, boroester groups are often important functional groups and can participate in various reactions such as Suzuki coupling reaction, thereby realizing the formation of carbon-carbon bonds for the construction of complex organic molecular structures. The 2-position amino group is nucleophilic and can participate in many nucleophilic reactions, such as reacting with acyl halides and acid anhydrides to form amides, etc., expanding the reaction path of compounds and enriching their chemical transformations. At the same time, due to the presence of pyridine ring, boron ester group and amino group, the compound has a certain polarity, which affects its solubility in different solvents, and its solubility in polar solvents is better than that in non-polar solvents. This property is of great significance for its synthesis, separation and application. Under specific conditions, the functional groups may interact and cooperate with each other, laying the foundation for applications in organic synthesis and medicinal chemistry.

2-Amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyridine, this compound has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate and can participate in many important organic reactions. The unique chemical activity of the structure of Gein boron heterocyclopentane makes the pyridine derivative can be combined with different organic halides through various coupling reactions to construct complex organic molecular structures, which is of great significance for the development of pharmaceutical chemistry, materials science and other fields.
In pharmaceutical chemistry, this compound may be used as a key structural fragment of the lead compound due to its unique structural properties. After appropriate modification and optimization, it may endow drugs with specific biological activities, such as targeting specific receptors and regulating enzyme activities, laying the foundation for the development of new drugs. At the same time, in the field of materials science, through the organic synthesis reactions it participates in, materials with special optoelectronic properties can be prepared, such as organic Light Emitting Diode materials, semiconductor materials, etc. Because the structure of the compound can be precisely regulated, it is helpful to optimize and customize the material properties to meet the needs of different application scenarios. In conclusion, 2-amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron-heterocyclopentane-2-yl) pyridine plays an important role in many scientific fields, promoting related technologies and research continue to advance.

To prepare 2-amino-5- (4, 4, 5, 5-tetramethyl-1, 3, 2-dioxyboropentyl-2-yl) pyridine, the following method can be followed.
First, 5-bromo-2-aminopyridine is used as the starting material, which is the foundation of the reaction. It is co-placed in the reaction kettle with diphenyl borate, base and suitable catalyst. Bases, such as potassium carbonate, can provide a suitable alkaline environment for the reaction to help the reaction proceed smoothly. The catalyst, commonly selected palladium catalysts, such as tetra (triphenylphosphine) palladium, can significantly accelerate the reaction rate and reduce the activation energy required for the reaction.
At a suitable temperature and reaction time, the boronation reaction occurs. This temperature often needs to be precisely controlled in a certain range, such as 80-100 ° C, and the time needs to be adjusted according to the actual situation, about 12-24 hours. During this reaction, the bromine atom of 5-bromo-2-aminopyridine will be substituted with diphenacol borate to form the target product 2-amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboropentyl-2-yl) pyridine.
After the reaction is completed, the reaction mixture needs to be post-processed. First extract with a suitable solvent, such as dichloromethane, ethyl acetate, etc., to separate the organic phase. After drying and concentrating, the solvent and impurities are removed. The product was purified by column chromatography or recrystallization to obtain 2-amino-5- (4, 4, 5, 5-tetramethyl-1, 3, 2-dioxyboroamyl-2-yl) pyridine with high purity.

2-Amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboran-2-yl) pyridine, which is a commonly used reagent in organic synthesis. When storing and transporting, many key points must be paid attention to.
First of all, storage is easy to be affected by the environment because of its nature, and the first thing to dry. Moist gas can easily cause it to deteriorate, so it should be stored in a dry place, such as in a desiccant with anhydrous calcium chloride and other desiccants. Furthermore, temperature is also critical, and it should be stored in a cool place, usually at 2-8 ° C. Excessive temperature may cause it to decompose. At the same time, it is necessary to avoid light, because it is sensitive to light, light exposure or chemical reaction, so it should be placed in a brown bottle, or wrapped in an opaque material.
As for transportation, the substance should be properly packaged. First, use a well-sealed container to ensure that there is no risk of leakage. Fill the surrounding buffer material, such as foam, cotton, etc., to prevent the container from being damaged due to collision during transportation. The transportation environment should not be ignored. Be sure to keep it dry and cool. Avoid co-transportation with water and strong oxidants, etc., because it may react violently with these substances. The quality and safety of 2-amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboropentyl-2-yl) pyridine can only be ensured with care during storage and transportation.

What I am asking you is the market price of 2-amino-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboronheterocyclopentane-2-yl) pyridine. However, the market price of this compound often changes due to many factors, making it difficult to determine the exact number.
First, the manufacturer and brand have a great influence on the price. A well-known and reputable big factory may have relatively high prices for its products due to high quality and exquisite craftsmanship; while a new factory or an unknown brand may have preferential prices in order to compete for the market.
Second, the purchase quantity is also the key. If you buy in bulk, merchants often offer discounts, small profits but quick turnover, and if you buy a large quantity, the price will be low; if you only buy a small amount for experimentation or small-scale use, the unit price will be higher.
Third, the state of market supply and demand determines the price. If demand is strong and supply is limited, if there is a surge in demand for this compound in a certain industry, the output will not keep up, and the price will rise; conversely, if supply exceeds demand, the price will tend to decline.
Fourth, the cost of raw materials is also related to the price of the production process. If the raw materials required for production are scarce, expensive, or the production process is complex, which consumes a lot of manpower, material resources, and financial resources, the price of the product will also rise.
Overall, in order to know the exact market price of this compound, it is necessary to consult the relevant chemical product suppliers in detail, compare the quotations of different merchants, and take into account the above factors to obtain more accurate price information.