2 Amino 4 Methylpyridine 3 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

2-amino-4-methylpyridine-3-carbonitrile

    Specifications

    HS Code

    997196

    Chemical Formula C7H7N3
    Molar Mass 133.15 g/mol
    Appearance Solid (usually a white to off - white powder)
    Melting Point Data needed (specific value depends on purity)
    Boiling Point Data needed (specific value depends on purity and pressure)
    Solubility In Water Poor solubility (organic nitriles and pyridines are generally sparingly soluble in water)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, dichloromethane
    Pka Data needed (related to its acidic or basic nature in solution)
    Density Data needed (specific value depends on physical state and purity)
    Flash Point Data needed (important for safety in handling as a potentially flammable substance)

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    General Information
    Where to Buy 2-amino-4-methylpyridine-3-carbonitrile in China?
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    Frequently Asked Questions

    As a leading 2-amino-4-methylpyridine-3-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-amino-4-methylpyridine-3-carbonitrile?
    2-Amino-4-methylpyridine-3-formonitrile is widely used in the chemical and pharmaceutical fields.
    In the chemical industry, it is a key intermediate in organic synthesis. It can participate in the construction of many complex organic molecular structures through specific chemical reactions. For example, in the synthesis of heterocyclic compounds, it can cleverly interact with various reagents to build the structure of pyridine derivatives. By reacting with nucleophiles, it can modify the substituents on the pyridine ring, expand the diversity of compounds, and lay the foundation for the creation of new materials and fine chemicals.
    In the field of medicine, this compound is of great value. Because of its unique chemical structure and activity, it has attracted much attention in the process of drug development. It may have potential biological activity and can be effective against specific disease targets. Many studies have been carried out around it, hoping to develop innovative drugs with excellent efficacy and mild side effects by modifying and optimizing its structure. For example, in the exploration of anti-tumor drugs, using it as a starting material, through multi-step reaction and structural modification, lead compounds with high selective inhibitory effect on tumor cells may be obtained, opening up new paths for the development of anti-cancer drugs. Or in the development of drugs for the treatment of neurological diseases, using its chemical properties to design and synthesize drugs that can modulate neurotransmitters and improve neurological function, providing new strategies for conquering such diseases.
    What are the physical properties of 2-amino-4-methylpyridine-3-carbonitrile?
    2-Amino-4-methylpyridine-3-formonitrile, this is an organic compound with unique physical properties. It is a white to light yellow crystalline powder, which is solid under normal conditions and has a fine texture. Its melting point is between 135 ° C and 139 ° C, and it melts into a liquid when heated to this temperature range.
    Regarding solubility, this compound exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF) and can be fused with it; however, in water, its solubility is very small, only a very small amount can be dissolved. This difference in solubility is related to the molecular structure. The polar groups contained in the molecule interact with the non-polar parts, resulting in different performances in different solvents.
    Furthermore, 2-amino-4-methylpyridine-3-formonitrile has certain stability, but in strong acid and strong base environments, the chemical structure may be affected, triggering reactions that cause structural changes. Its stability is derived from the distribution of chemical bonds and electron clouds in the molecule, and it can maintain its own structure under normal conditions.
    In addition, this compound has absorption properties under specific wavelengths of light, and absorption peaks can be observed in ultraviolet-visible spectroscopy, which can be used for qualitative and quantitative analysis. This property is of great significance in the field of chemical analysis, assisting researchers in accurately determining its content and purity, and laying the foundation for further research and application.
    2-amino-4-methylpyridine-3-carbonitrile chemical synthesis methods
    For the chemical synthesis of 2-amino-4-methylpyridine-3-formonitrile, there are many paths to follow.
    First, the corresponding pyridine derivative can be initiated. First, take a suitable pyridine compound, whose structure needs to be related to the target product, such as those with a specific substituent distribution. Take a pyridine derivative as raw material and introduce an amino group under appropriate reaction conditions. This process can be selected from a suitable amination reagent, such as ammonia or an amino-containing compound. During the reaction, factors such as reaction temperature, time and proportion of reactants need to be strictly controlled. In general, in a specific solvent environment, the temperature is raised to a certain extent, so that the amination reagent can fully react with the pyridine derivative to form an amino-containing pyridine intermediate.
    Then, for the intermediate, the methonitrile group is introduced. This step can be achieved with the help of specific reagents, such as cyanoactive compounds. Similarly, the reaction conditions need to be carefully regulated to ensure that the cyano group is precisely connected to the target position of the pyridine ring, that is, the No. 3 position, so as to obtain 2-amino-4-methylpyridine-3-formonitrile.
    Second, the pyridine ring can also be constructed from the basic raw material through multi-step reaction, and then the synthesis of the target product can be achieved. First select simple organic compounds that can be used to construct pyridine rings, such as small molecules containing nitrogen and carbon. Through multi-step organic reactions, the skeleton of the pyridine ring is gradually built. In the process of constructing the pyridine ring, the introduction position and order of amino and methyl groups are considered at the same time. For example, the condensation reaction, cyclization reaction and other means can be used to gradually form the pyridine ring, and the 2-amino and 4-methyl groups are introduced in sequence. Finally, the methylnitrile group is introduced at the 3-position of the pyridine ring to achieve the synthesis of 2-amino-4-methylpyridine-3-methylnitrile. Although there are many steps in this path, it can precisely control the position and properties of each substituent on the pyridine ring, which is conducive to improving the purity and yield of the product.
    The above synthesis methods need to carefully select the reaction conditions and reagents according to the actual situation to achieve the best synthesis effect.
    2-amino-4-methylpyridine-3-carbonitrile What are the precautions in storage and transportation?
    2-Amino-4-methylpyridine-3-formonitrile is a chemical substance, and many points need to be paid special attention when storing and transporting.
    First, let's talk about storage. Because it may have specific chemical activity and stability, it needs to be stored in a cool, dry and well-ventilated place. This is to avoid chemical reactions caused by excessive moisture and heat in the environment, such as hydrolysis by moisture or decomposition by heat. The temperature of the storage place should be kept stable, away from heat sources and fire sources, to prevent dangerous reactions triggered by high temperature. After all, many chemicals have greatly increased reactivity at high temperatures, which can easily lead to safety accidents. Moreover, they should be stored separately from oxidants, acids, bases, etc. This is because the structural characteristics of 2-amino-4-methylpyridine-3-formonitrile make it possible to react violently with these substances, such as contacting with oxidants or triggering oxidation reactions, reacting with acids and bases or changing their chemical properties, and may even produce toxic and harmful gases. At the same time, the storage area should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment to prepare for emergencies. If there is a sudden leakage and other situations, it can be dealt with in time to reduce the harm.
    As for transportation, ensure that the packaging is complete and sealed. Good packaging can prevent material leakage and avoid harm to the transportation environment and personnel. The transportation process must be handled with care and should not be handled brutally, because it may cause damage to the packaging and cause material leakage. Moreover, the transport vehicle needs to be clean, dry, and free of other residual substances that may react with it. In addition, transport personnel should be familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident such as a leak during transportation, they can respond quickly and correctly to reduce the harmful consequences.
    In short, whether it is storing or transporting 2-amino-4-methylpyridine-3-formonitrile, it is necessary to operate in strict accordance with regulations, have a full understanding of its chemical properties, and treat every link with caution to ensure safety and avoid accidents.
    What is the market price range for 2-amino-4-methylpyridine-3-carbonitrile?
    2-Amino-4-methylpyridine-3-formonitrile is an important intermediate in organic synthesis. Its price range in the market is difficult to determine, and it is subject to many factors.
    First of all, the raw material supply end, the preparation of this compound is the starting material of Chang Lai. If the raw material supply is abundant and the price is stable, the cost of 2-amino-4-methylpyridine-3-formonitrile is controllable, and the price may be in a lower range. On the contrary, if the raw material is scarce, or the supply is suddenly reduced due to natural disasters, geopolitics, etc., the price will rise.
    Furthermore, the difficulty of the preparation process is also the key. If the synthesis process is simple, the energy consumption and waste output are low, and the yield is considerable, the cost will drop and the market price will follow. However, if the process is complicated, special equipment and catalysts are required, and the reaction conditions are harsh, the cost will increase greatly and the selling price will also be high.
    Changes in market demand also affect its price. If it is in high demand in fields such as medicine, pesticides or materials science, and the supply is in short supply, merchants will raise prices to make a profit. On the contrary, if the demand is low, the supply exceeds the demand, and the price will drop.
    In addition, the market competition situation also affects the price. If there are many market participants and the competition is fierce, each merchant will compete for a share or lower the price. On the contrary, if the market is monopolistic and there are few suppliers, the pricing power will be in the hands of the few, and the price may remain high.
    Overall, the market price range of 2-amino-4-methylpyridine-3-formonitrile, or depending on time and place, ranges from a few yuan per gram to several hundred yuan. It is difficult to generalize. It is necessary to study all factors carefully to obtain a more accurate price.