2 Amino 4 Methoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-4-methoxypyridine

    Specifications

    HS Code

    209917

    Chemical Formula C6H8N2O
    Molar Mass 124.14 g/mol
    Appearance Solid
    Color White to off - white
    Odor May have a faint amine - like odor
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, acetone
    Melting Point 106 - 108 °C
    Pka Appropriate pKa values for pyridine - based amines

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    General Information
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    Frequently Asked Questions

    As a leading 2-Amino-4-methoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Amino-4-methoxypyridine?
    2-Amino-4-methoxypyridine is used in various fields such as chemical industry and medicine.
    In the chemical industry, it is a key raw material for the synthesis of many fine chemicals. Because of its specific chemical structure and active reactivity, it can participate in a variety of organic synthesis reactions, such as nucleophilic substitution and cyclization. With this, compounds with complex structures and unique properties can be prepared, providing diverse possibilities for the development of dyes, fragrances and other products.
    In the field of medicine, this compound is of great significance. It may be the core structural unit of drug molecules and is essential for the development of new drugs. After modification and modification, substances with specific pharmacological activities can be obtained. For example, some compounds based on this, or effective in the treatment of specific diseases, such as anti-tumor, anti-virus, etc., can make great contributions to human health.
    Furthermore, 2-amino-4-methoxypyridine has also emerged in the field of materials science. Due to its good electron transport properties and chemical stability, it can be applied to the preparation of organic semiconductor materials for electronic devices such as organic Light Emitting Diodes and field effect transistors, promoting the progress of materials science.
    In summary, although 2-amino-4-methoxypyridine is an organic compound, it has a wide range of uses and plays an indispensable role in many important fields, with broad prospects and great potential.
    What are the physical properties of 2-Amino-4-methoxypyridine?
    2-Amino-4-methoxypyridine is a kind of organic compound. It has many physical properties, which are described in detail below.
    Looking at its properties, under normal temperature and pressure, 2-amino-4-methoxypyridine is white to pale yellow crystalline powder with fine texture. This form is conducive to storage and use, and is also convenient for accurate measurement in many chemical reactions.
    When it comes to melting point, it is between 128-132 ° C. The characteristics of melting point are crucial for the identification and purity judgment of compounds. Accurate determination of melting point can help to distinguish the authenticity of the substance, and the higher the purity, the narrower the melting point range. < Br >
    Its solubility is also a key physical property. This compound is slightly soluble in water, but it can be soluble in common organic solvents such as ethanol, methanol, dichloromethane, etc. This solubility property makes it possible to choose a suitable solvent according to the needs of the reaction in organic synthesis to promote the smooth progress of the reaction. For some reactions that need to occur in non-aqueous systems, soluble organic solvents can be selected as the reaction medium to provide a good environment for the reaction.
    Furthermore, 2-amino-4-methoxypyridine has certain stability. However, under extreme conditions such as high temperature, strong acid, and strong base, its structure may be damaged, causing chemical properties to change. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, and avoid mixing with strong acids, alkalis and other substances.
    In addition, the compound may have a specific odor, but the relevant odor description literature is less recorded, and it is speculated that its odor is not very strong. However, during operation, it is still necessary to pay attention to ventilation to prevent inhalation of volatile substances that may affect the human body.
    In summary, the physical properties of 2-amino-4-methoxypyridine are of great significance for its application in organic synthesis, medicinal chemistry and other fields. Its properties, melting point, solubility and stability provide an important basis for its operation and use in various chemical reactions and practical applications.
    What are 2-Amino-4-methoxypyridine synthesis methods?
    The synthesis method of 2-amino-4-methoxypyridine has been known for a long time. I hope the above numerical method will help.
    First, 4-methoxypyridine is used as the starting material, and 4-methoxy-2-nitropyridine can be obtained by nitrification. In this step, it is necessary to choose a suitable nitrifying agent, such as mixed acid, to control the temperature and time of the reaction to achieve optimal production. Following the reduction technique, iron powder, zinc powder and other metals are often selected to co-produce with acids, or by catalytic hydrogenation to make nitro groups into amino groups, and then 2-amino-4-methoxypyridine is obtained.
    Second, using 2-halo-4-methoxy pyridine as raw material. The halogen atom has good activity and can react with ammonia or amine reagents in a nucleophilic substitution reaction. Choose liquid ammonia or organic amine, and under suitable temperature and pressure, the halogen atom is replaced by an amino group to obtain the target product. However, attention should be paid to the selectivity of the reaction and the control of side reactions.
    Third, methoxy and amino groups are gradually constructed from compounds containing pyridine rings. If a methoxy group is introduced first, reactions such as nucleophilic substitution or Fu-gram alkylation can be used. After the amination method, according to different reaction paths, such as diazotization-reduction and other means, amino groups are introduced to form 2-amino-4-methoxypyridine. This approach is a little complicated, but if the design is exquisite, high-purity products can also be obtained.
    All synthesis methods have advantages and disadvantages. In practice, when the raw materials are easy to obtain, the cost is high and low, and the purity of the product is required, the best conditions can be achieved by carefully selecting them.
    What 2-Amino-4-methoxypyridine need to pay attention to when storing and transporting
    2-Amino-4-methoxypyridine is an organic compound. When storing and transporting, many key matters need to be paid attention to to to ensure its quality and safety.
    First, the storage temperature must be carefully controlled. This compound is suitable for storage in a cool place, away from heat sources and open flames. High temperature can easily cause chemical reactions, and even cause combustion and explosion. Due to the increase in temperature, the molecular activity is enhanced, and the reaction activity is also increased, which is easy to induce uncontrollable changes. Therefore, an environment with relatively stable temperature and low temperature should be selected. If placed in a cool warehouse, the warehouse temperature should be maintained between 15-25 ° C.
    Second, moisture resistance is extremely important. 2-Amino-4-methoxypyridine has certain hygroscopicity. If it is damp, or its purity is reduced, it may also cause reactions such as hydrolysis and damage its chemical structure. Therefore, the storage place must be dry. A desiccant, such as anhydrous calcium chloride, silica gel, etc. can be placed around the storage container to absorb water vapor in the air. And after taking it, the container should be quickly sealed to prevent moisture from invading.
    Third, the choice of storage container cannot be ignored. Corrosion-resistant materials, such as glass, specific plastics, etc. Due to its active chemical properties, it may react with certain metal materials, causing corrosion of the container and affecting the quality of the compound. For example, do not store in iron containers to prevent chemical reactions between iron and compounds.
    Fourth, when transporting, ensure that the packaging is tight. Use special chemical transportation packaging to strengthen the packaging to avoid damage to the packaging due to collision and vibration during transportation, which may cause danger from leakage. At the same time, transportation vehicles should also be equipped with corresponding safety measures, such as fire extinguishers, leakage emergency treatment equipment, etc. Transport personnel also need to undergo professional training, familiar with the characteristics of this compound and emergency treatment methods.
    In summary, the storage and transportation of 2-amino-4-methoxypyridine requires careful handling in terms of temperature, humidity, packaging, and transportation to ensure that its safety and quality are not compromised.
    What is the market price of 2-Amino-4-methoxypyridine?
    2-Amino-4-methoxypyridine, an organic compound, has important uses in many fields such as chemicals and medicine. However, its market price is difficult to determine with certainty, because many factors will affect it.
    First, the market supply and demand relationship, which is the key factor affecting its price. If the market demand for 2-amino-4-methoxypyridine is strong, but the supply is relatively short, the price will rise; conversely, if the market demand is weak and the supply is sufficient, the price will easily drop.
    Second, the production cost should not be underestimated. The price of raw materials, the complexity of the production process, and energy consumption will all affect the final cost. Rising raw material prices, or the high cost of the production process, will lead to higher product prices.
    Third, product quality and purity are also closely related to price. High-purity, high-quality 2-amino-4-methoxypyridine is usually more expensive because it is indispensable in some high-end application scenarios.
    Fourth, the market competition situation also has an impact. If there are many companies producing this product in the market, the competition is fierce, and the companies compete for a share, the price may be appropriately reduced; conversely, if the market is almost monopolized, the price may be relatively high.
    According to past market conditions and related information, the price of 2-amino-4-methoxypyridine may range from tens to hundreds of yuan per kilogram. However, this is only a rough range, and the true price depends on the actual market situation. For accurate prices, please consult the relevant chemical product suppliers or refer to the quotation information of professional chemical product trading platforms.