2-amino-3-nitropyridine

2-Amino-3-nitropyridine is 2-amino-3-nitropyridine, which has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique chemical structure, it can participate in various chemical reactions, synthesize specific bioactive compounds, and help create new drugs in the process of drug development.
In the field of materials science, it also has important functions. With its structural properties, it can be used to prepare materials with special electrical and optical properties. For example, after specific processing, the material can exhibit unique photoelectric conversion efficiency, which has potential application value in the manufacture of optoelectronic devices such as solar cells and Light Emitting Diodes.
Furthermore, in the field of organic synthesis, 2-amino-3-nitropyridine, as a key building block, participates in the construction of complex organic molecules. Due to the activity of amino and nitro groups, it can expand the molecular structure complexity through various reaction pathways and interact with different reagents, providing the possibility for the synthesis of novel organic compounds, which is of great significance to the development of organic synthesis chemistry.

2-Amino-3-nitropyridine is an organic compound with specific physical properties. It is a yellow to orange crystalline powder that is stable at room temperature and pressure.
The melting point is about 159-162 ° C. The important thing about the melting point is that it can help determine the purity of the substance. If the purity of the substance is high, the melting point range is narrow; if there are many impurities, the melting point will be reduced and the range will be wider. The melting point of this compound is in this range, indicating that it has certain purity characteristics.
In terms of solubility, it is slightly soluble in water. This is because water is a polar solvent. Although 2-amino-3-nitropyridine contains polar groups amino and nitro, the existence of the pyridine ring makes its overall polarity not very high, so it is difficult to dissolve in water. However, it is soluble in some organic solvents, such as ethanol and dichloromethane. Ethanol has moderate polarity and can interact with this compound by hydrogen bonds; dichloromethane has moderate polarity and good solubility, which can disperse 2-amino-3-nitropyridine.
The density of 2-amino-3-nitropyridine is about 1.48 g/cm ³. Density as a material characteristic can be used for substance identification and separation. When the mixture is separated, if the density of each substance varies greatly, it can be separated by gravity sedimentation or centrifugation. The density value of this compound reflects the relationship between its relative mass and volume, which helps to understand its physical behavior in actual operation.
In addition, the compound has a certain odor. Although it has no pungent odor, it also has a unique smell, but the relevant odor description data is relatively small. It is a solid at room temperature and pressure, and has good stability. When it encounters strong oxidizing agents, strong acids, and strong bases, or chemical reactions occur, resulting in changes in structure and properties. During practical application and storage, care should be taken to avoid contact with such substances to prevent deterioration.

The synthesis method of 2-amino-3-nitropyridine has been explored by many parties throughout the ages. The following are several common methods.
First, pyridine is used as the starting material. First, pyridine is nitrified to introduce nitro groups. Pyridine can be obtained under the action of mixed acid of sulfuric acid and nitric acid. This reaction needs to pay attention to the reaction temperature and acid concentration. If the temperature is too high or the acid concentration is improper, it is easy to cause side reactions to occur. Then, 3-nitropyridine is reduced and aminated to introduce amino groups. In the reduction step, you can choose to reduce the nitro group under acidic conditions such as iron powder and zinc powder, or use the catalytic hydrogenation method to reduce the nitro group with palladium carbon as a catalyst. During amination, halogenation reagents can be used to halogenate the appropriate position on the pyridine ring first, and then react with ammonia or amine compounds to introduce amino groups.
Second, 2-aminopyridine is used as the raw material. React 2-aminopyridine with a suitable nitrifying reagent to directly introduce nitro groups. This path is relatively simple, but the reaction conditions need to be precisely controlled. Due to the positioning effect of amino groups, the problem of selectivity of nitro introduction may be caused. Use mild nitrifying reagents, such as acetyl nitrate, and react at low temperature to improve the selectivity of 2-amino-3-nitropyridine.
Third, through heterocyclic synthesis. With suitable nitrogen and carbon-containing raw materials, pyridine rings are formed by cyclization reaction, and amino and nitro groups are introduced at the same time. For example, some nitrogen and carbonyl-containing compounds are synthesized by a series of reactions such as condensation and cyclization under specific catalysts and reaction conditions. This method requires in-depth understanding of the reaction mechanism, and the reaction conditions are more complex, but sometimes more efficient synthesis can be achieved.
All kinds of synthesis methods have their own advantages and disadvantages, and they need to be carefully selected according to the actual situation, such as the availability of raw materials, the controllability of reaction conditions, and the purity requirements of the product, in order to achieve the desired synthesis effect.

2-Amino-3-nitropyridine is a chemical substance. During storage and transportation, many matters must be paid attention to.
First word storage. This substance should be stored in a cool, dry and well-ventilated place. Due to high temperature and humidity, it may cause its properties to change. Keep away from fire and heat sources to prevent the risk of fire. It is more sensitive to heat. Under high temperature, it may decompose or explode. Furthermore, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. The reason is that 2-amino-3-nitropyridine encounters with such substances, which is prone to chemical reactions, damage its quality, and even cause danger. And the storage place should be equipped with suitable materials to contain leaks. If there is any accidental leakage, it can be disposed of in time.
As for transportation. Before transportation, make sure that the packaging is complete and sealed. If the packaging is damaged and the material leaks, it will not only damage the environment, but also increase the danger. During transportation, the speed of the vehicle should not be too fast to avoid bumps and vibrations to prevent damage to the packaging. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. If there is a leak on the way, it can be dealt with immediately. At the same time, the transportation personnel should also be familiar with the characteristics of 2-amino-3-nitropyridine and emergency treatment methods, so as to ensure the safety of storage and transportation.

2-Amino-3-nitropyridine is also a chemical substance. Its market price situation is quite complex and varies due to a variety of factors.
In the past, the price of this chemical often fluctuated due to the supply and demand of raw materials and the difficulty of preparation. If the production of raw materials is unfavorable or the origin changes, its price will be affected. If the new method of preparation is developed, the cost will be reduced, and the price will also decrease.
In addition, market demand is also the key. If an industry is booming, the demand for 2-amino-3-nitropyridine will increase sharply, and the price will rise; on the contrary, if the demand is sluggish, the price will decline.
Furthermore, the difference in geography is also related to the price. In places with convenient transportation and the prosperity of the chemical industry, the price may be slightly lower due to the convenience of transportation and the efficiency of scale; and in remote places, due to the high transportation cost, the price is often high.
If you want to know the exact market price at present, you should check the chemical product trading platform carefully, or consult industry experts and manufacturers to obtain accurate figures to understand the market price.