2 Amino 3 Nitro 5 Bromopyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-3-Nitro-5-Bromopyridine

    Specifications

    HS Code

    116532

    Chemical Formula C5H4BrN3O2
    Molar Mass 219.99 g/mol
    Appearance Solid (color may vary)
    Physical State At Room Temp Solid
    Solubility In Water Low (due to non - polar aromatic nature)
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, chloroform

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    General Information
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    Frequently Asked Questions

    As a leading 2-Amino-3-Nitro-5-Bromopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-Amino-3-Nitro-5-Bromopyridine?
    2-Amino-3-nitro-5-bromopyridine is one of the organic compounds. Its physical properties are very critical and are of great significance in the fields of chemical industry and scientific research.
    This compound is mostly solid at room temperature. Looking at its appearance, it is often a white-like to light yellow crystalline powder with a pure color and fine texture. Its melting point has a fixed number and is about a certain temperature range. The exact value of this temperature range often depends on accurate experimental determination. The characteristics of the melting point can be used to identify this substance and also have a great impact on its storage and use.
    When it comes to solubility, 2-amino-3-nitro-5-bromopyridine has different solubility in organic solvents. In some polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it has good solubility and can be uniformly dispersed to form a homogeneous solution. However, in non-polar organic solvents, such as n-hexane and toluene, the solubility is poor and it is difficult to dissolve and disperse. In water, its solubility is also limited, and it is slightly soluble in water. This difference in solubility is due to the interaction of polar and non-polar groups in its molecular structure.
    In addition, the stability of 2-amino-3-nitro-5-bromopyridine is also an important physical property. It can exist stably in a dry and dark environment at room temperature and pressure. However, in case of high temperature, humidity or strong oxidation and strong reduction conditions, its structure may change, resulting in changes in its properties. Therefore, when storing, it is necessary to choose suitable conditions to ensure the stability of its properties.
    It can be seen from the above that the physical properties of 2-amino-3-nitro-5-bromopyridine, such as appearance, melting point, solubility, stability, etc., play a decisive role in its application in chemical synthesis, drug research and development, etc. People in scientific research and industrial production need to know its physical properties in order to make good use of it.
    What are the main uses of 2-Amino-3-Nitro-5-Bromopyridine?
    2-Amino-3-nitro-5-bromopyridine, which is a crucial chemical substance in the field of organic synthesis, has a wide range of uses.
    First, in the field of medicinal chemistry, it is often used as a key intermediate. The specific substituent of 2-amino-3-nitro-5-bromopyridine can be precisely introduced into the molecular structure of the target drug through a series of organic reactions. For example, in the synthesis of some antibacterial drugs and anti-tumor drugs, this compound is used to construct key pharmacoactive groups, thereby endowing the drug with specific biological activities and pharmacological properties.
    Second, in the field of materials science, it also has its uses. After appropriate chemical modification, it can be integrated into the structure of polymers or functional materials. In this way, the electrical and optical properties of materials can be regulated. For example, the preparation of organic semiconductor materials with special photoelectric response, 2-amino-3-nitro-5-bromopyridine can be used as a structural unit to improve the carrier transport characteristics and light absorption properties of materials, providing assistance for the development of organic optoelectronic devices.
    Third, in the fine chemical industry, it is used as a raw material for the synthesis of a variety of fine chemicals. Such as the synthesis of special structures of dyes, pigments, etc. Its unique molecular structure can generate compounds with rich colors and special properties in subsequent reactions, meeting the needs of fine chemicals in different industrial fields.
    In short, 2-amino-3-nitro-5-bromopyridine, with its unique structure, plays an indispensable role in the fields of drugs, materials, fine chemicals, etc., and promotes the technological progress and innovation of related industries.
    What are 2-Amino-3-Nitro-5-Bromopyridine synthesis methods?
    There are various methods for synthesizing 2-amino-3-nitro-5-bromopyridine in ancient times. One method is to first take the pyridine as the group and add a brominating agent to it, so that the bromine atom is added at a specific position, that is, the 5 position. The bromination process requires careful observation of the reaction conditions, such as temperature and solvent properties, which are all related to the effect of bromination. After bromination, proceed with nitrification. When nitrifying, choose the appropriate nitrifying agent, control the dosage and reaction time, so that the nitro can be introduced into the 3 positions. After the method of amination, the appropriate group is replaced by an amino group to obtain 2-amino-3-nitro-5-bromopyridine.
    There are other methods, or start with pyridine, nitrate first, so that the nitro group enters the 3rd position. Then bromide, so that the bromine atom falls into the 5th position. Finally, by means of amination, a specific group is replaced with an amino group, and the final product is the target.
    There are also those who use other substances as the starting material and pass through several steps to synthesize this compound. For example, starting from a compound with a specific substituent, through the conversion and rearrangement of functional groups, the pyridine ring is gradually constructed, and amino, nitro and bromine atoms are introduced in the corresponding positions.
    All these synthesis methods have their own advantages and disadvantages. Or the reaction conditions are harsh, or the steps are complicated, or the yield is not ideal. However, chemists are constantly studying, striving to find better methods to improve the efficiency of its synthesis, reduce its cost, and reduce its impact on the environment.
    What are the precautions in storage and transportation of 2-Amino-3-Nitro-5-Bromopyridine?
    2-Amino-3-nitro-5-bromopyridine is an organic compound. When storing and transporting, the following matters must be carefully noted:
    First, the storage environment is very important. This compound should be stored in a cool, dry and well-ventilated place. The cool environment can prevent it from decomposing or other chemical reactions due to excessive temperature; the dry place can avoid moisture, which may affect its own quality or even cause deterioration; the well-ventilated can disperse the harmful gases that may be generated in time to ensure the safety of the storage space.
    Second, the packaging must be tight. Appropriate packaging materials, such as sealed containers, must be used to prevent them from coming into contact with external factors such as air and moisture. Good sealing can prevent volatilization, oxidation and other conditions, and ensure the purity and stability of the compound.
    Third, the transportation process should not be underestimated. Violent vibration and collisions should be avoided to avoid compound leakage due to package damage. If the bumps and vibrations during transportation are too severe, it may cause the packaging container to break, thereby exposing the compound to the outside world, which may not only pollute the environment, but also pose a threat to the safety of transporters.
    Fourth, strictly separate storage and transportation from oxidants, acids, alkalis and other substances. This is due to the chemical properties of 2-amino-3-nitro-5-bromopyridine, which may react violently with the above substances, which may cause serious consequences such as fire and explosion.
    Fifth, storage and transportation sites should be equipped with corresponding fire and leakage emergency treatment equipment. In the event of an unexpected situation, such as fire or leakage, response measures can be taken quickly to reduce losses and hazards. Such as fire extinguishing equipment should be reasonably configured according to the characteristics of the compound, and leakage emergency treatment equipment should be complete and readily available.
    In conclusion, the storage and transportation of 2-amino-3-nitro-5-bromopyridine requires all-round care to ensure the safety of personnel, the environment is not contaminated, and the quality of the compound is not compromised.
    What is the market price of 2-Amino-3-Nitro-5-Bromopyridine?
    The market price of 2-amino-3-nitro-5-bromopyridine is difficult to determine. This is due to the capriciousness of the market, and its price varies with many factors.
    First, the supply and demand situation has a huge impact on the price. If there are many people who want it, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price will drop automatically. At present, the chemical industry, medicine and other industries may need it. If the industry is prosperous and the demand increases greatly, the price will also rise.
    Second, the price of raw materials also affects its market price. When preparing this pyridine derivative, if the price of the raw materials used fluctuates, the price of the finished product will also be difficult to stabilize. If the price of raw materials rises, in order to ensure profitability, the producer must raise the price of this product.
    Third, the preparation method and cost are also related to the price. If a new efficient and low-cost method is developed, the cost of the manufacturer will drop, and the price will drop accordingly; if the preparation is difficult and the cost is high, the price will be high.
    Fourth, the competition in the market is also the key. If there are many producers and the competition is fierce, they may compete with the price to occupy the market, so that the price will be lower; if the market is monopolized and there are few producers, the pricing power is in their hands, and the price may be higher.
    Looking at the changes in the prices of chemical products in the past, the prices of such compounds fluctuated greatly. However, to know their exact market price, you should consult chemical raw material suppliers, traders, or professional chemical product trading platforms to obtain a recent and accurate price.