2-Amino-3-nitro-4-methylpyridine

2-Amino-3-nitro-4-methylpyridine is widely used in various fields of chemistry.
First, in the field of pharmaceutical chemistry, it is often a key intermediate for the creation of new drugs. Due to the characteristics of amino groups, nitro groups and methyl groups in the molecular structure, compounds with specific pharmacological activities can be constructed by chemical modification. For example, after modification, it may be able to bind to specific receptors, thereby exhibiting antibacterial, anti-inflammatory and other pharmacological effects, providing an important basis for the development of new drugs.
Second, in the field of materials science, it can participate in the synthesis of functional materials. By polymerizing with other monomers, its unique structure is introduced into the polymer skeleton, imparting special electrical, optical or thermal properties to the material. Or it can make the material exhibit absorption or emission characteristics of specific wavelengths of light, which is used in the field of optical materials.
Third, in organic synthetic chemistry, this compound is often used as a key building block. Because of its activity check point of its structure, it can construct more complex organic molecular structures through various chemical reactions, such as nucleophilic substitution, electrophilic substitution, etc., to expand the diversity of organic compounds and provide an effective path for the synthesis of organic materials with special structures and properties.
In conclusion, 2-amino-3-nitro-4-methylpyridine, with its unique molecular structure, plays an important role in many fields such as drug development, material creation, and organic synthesis, and has made significant contributions to the development of chemistry-related fields.

2-Amino-3-nitro-4-methylpyridine is one of the organic compounds. Its physical properties are quite important and are relevant in various fields of chemistry.
First of all, its appearance is usually in a solid state. This is a common physical property and can be seen visually. Looking at its color, it is mostly yellowish. This color characteristic is also one of the aids in identifying this substance.
As for the melting point, this is the key physical property. The melting point of 2-amino-3-nitro-4-methylpyridine is within a specific range, and this value is of great significance for the identification of its purity and the study of heat changes. Due to the deviation of the melting point of different purity products, the purity can be determined by the melting point measurement.
Solubility is also a property that cannot be ignored. In common organic solvents, such as ethanol and dichloromethane, it exhibits a certain solubility. This property determines its application in chemical reactions and separation and purification operations. In ethanol, the corresponding reaction system can be designed according to its degree of solubility, or the separation technique can be performed by means of dissolution differences.
Furthermore, the density of this material is also an inherent physical property. The value of density can help to calculate the balance of materials and predict the distribution of positions in the mixed system. In the design of many chemical processes, density data is indispensable, which is related to the selection of reaction vessels and the accurate calculation of material ratio.
Its volatility is relatively low, and it is not easy to evaporate into the atmosphere under normal conditions. This property makes storage and operation more convenient, reducing the risk of loss due to volatilization and environmental hazards.
The physical properties of 2-amino-3-nitro-4-methylpyridine, such as appearance, melting point, solubility, density and volatility, have a key impact on its chemical research, industrial applications and related operations, and are indispensable information in the exploration and practice of organic chemistry and related fields.

For the chemical synthesis of 2-amino-3-nitro-4-methylpyridine, there are several common routes. First, the corresponding pyridine derivative can be started, and the nitro group can be introduced by nitrification reaction. First, take the appropriate 4-methyl pyridine derivative, and under suitable reaction conditions, use the mixed acid system of nitric acid and sulfuric acid as the nitrifying agent, carefully control the temperature, add the mixed acid dropwise, so that the nitro group can be selectively introduced into the 3-position of the pyridine ring. This step requires careful operation. Due to the intense nitrification reaction and the special distribution of the electron cloud in the pyridine ring, the reaction conditions need to be precisely adjusted to obtain the desired 3-nitro substitution product.
Then, for the obtained 3-nitro-4-methylpyridine derivatives, an amination reaction is carried out. This can be done by ammonolysis or other methods, using liquid ammonia or organic amines as the amino source, and heating the reaction in the presence of a catalyst. The choice of catalyst is crucial, such as some metal salts or organic bases, which can effectively promote the nucleophilic substitution of amino groups at specific positions on the pyridine ring, thereby introducing amino groups, and finally obtaining 2-amino-3-nitro-4-methylpyridine.
Another strategy is to first build the basic structure of the pyridine ring, and then gradually introduce the required substituents. For example, with suitable nitrogen and carbon raw materials, a pyridine ring is constructed through a series of reactions such as condensation and cyclization. During the cyclization process, the reaction conditions and raw material structure are cleverly designed so that the pyridine ring can reserve an active check point for further reaction at the target position. Subsequently, nitro and amino groups are introduced into the pyridine ring according to the order of first nitrification and later amination to achieve the purpose of synthesizing the target product. This approach requires in-depth understanding of the reaction mechanism and raw material activity in order to accurately control each step of the reaction and obtain a high-purity product. In conclusion, the synthesis of 2-amino-3-nitro-4-methylpyridine requires meticulous planning of reaction routes and precise regulation of reaction conditions at each step to achieve the goal of efficient and highly selective synthesis.

2-Amino-3-nitro-4-methylpyridine is an important organic compound. When storing and transporting, many matters need to be paid careful attention.
Primary storage environment. This compound should be stored in a cool, dry and well-ventilated place. Avoid heat sources, fire sources and strong oxidants, because it is heated or exposed to strong oxidants, or there is a risk of violent reaction or even explosion. The warehouse temperature should be maintained within a suitable range to prevent it from decomposing or causing other chemical changes due to excessive temperature.
Secondary packaging material. Suitable packaging materials should be used to ensure sealing and stability. Commonly used sealed containers, such as glass bottles, plastic bottles or metal drums. The packaging material should have no chemical reaction with the compound to prevent the package from being damaged and causing it to leak.
Further transportation requirements. During transportation, it is necessary to ensure that the package is complete and stable, and to avoid collisions and vibrations to prevent package damage. The transportation tools should also be clean and dry, and there are no impurities that may react with the compound. At the same time, the transportation personnel should be familiar with its nature and emergency treatment measures, and can properly deal with emergencies.
In addition, whether it is storage or transportation, relevant regulations and safety standards must be strictly followed. Equipped with corresponding safety facilities and emergency rescue equipment, such as fire extinguishers, eye washers, protective gloves, etc. Professional training for operators to master correct operation methods and safety precautions. In this way, the safety of 2-amino-3-nitro-4-methylpyridine during storage and transportation can be ensured, reducing the risk of accidents.

The market price range of 2-amino-3-nitro-4-methylpyridine is difficult to determine with certainty. The price often varies due to various factors, such as the cost of raw materials, the production process, the supply and demand of the market, and the quality.
Looking at the cost of raw materials in the past, if the price of basic raw materials required for its preparation is high, or the supply of raw materials is short, resulting in higher production costs, the price of this product will also rise. And different production processes have different complexities, energy consumption and output rates. A delicate and efficient process may reduce costs and affect prices.
The market supply and demand situation is also key. If many industries have strong demand for it and limited supply, the price will rise; conversely, if the demand is low and the supply is excessive, the price will decline. Furthermore, the quality of the products is different, those with high purity and high quality are often higher than those with ordinary quality.
Due to the above factors, it is difficult to have an exact price range. For more information, please consult the supplier specializing in this chemical or the chemical product trading platform, or you can get the current price information.