2 Amino 3 Nitro 4 Methyl 5 Fluoropyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-3-nitro-4-methyl-5-fluoropyridine

    Specifications

    HS Code

    144409

    Chemical Formula C6H6FN3O2
    Appearance Solid (usually powder)

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    General Information
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    Frequently Asked Questions

    As a leading 2-Amino-3-nitro-4-methyl-5-fluoropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 2-Amino-3-nitro-4-methyl-5-fluoropyridine?
    2-Amino-3-nitro-4-methyl-5-fluoropyridine, this is an organic compound. Its chemical properties are unique and allow me to elaborate.
    Looking at its structure, amino, nitro, methyl and fluorine atoms are all attached to the pyridine ring. Amino is basic, because its nitrogen atom has lone pair electrons, it can accept protons, and it is easy to combine with protons to form cations in acidic environments. This property makes it possible to participate in many acid-base reactions.
    Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the pyridine ring and reduce the activity of electrophilic substitution on the ring. And the presence of nitro groups makes the compound oxidizing to a certain extent. When encountering reducing agents, nitro groups can be reduced to form amino groups or other reduced nitrogen-containing groups.
    methyl is a donator group. Although the donator ability is relatively weak, it can also affect the distribution of electron clouds in the pyridine ring, which increases the density of electron clouds in the adjacent and para-position, and has a certain effect on the selectivity of the reaction check point.
    Fluorine atoms have large electronegativity and have a strong electron-absorbing induction effect. They not only change the electron cloud density of the pyridine ring, but also have a significant impact on the physical and chemical properties of the molecule. For example, by enhancing the polarity of the molecule, it affects its solubility, melting point, boiling point and other physical properties. < Br >
    In chemical reactions, the compound can exhibit diverse reactivity due to the interaction of various groups. Amino groups can participate in acylation, alkylation and other reactions; nitro groups can be reduced; pyridine rings can also undergo nucleophilic substitution and other reactions. Its unique chemical properties make it potentially valuable in organic synthesis, medicinal chemistry and other fields.
    What are the main uses of 2-Amino-3-nitro-4-methyl-5-fluoropyridine?
    2-Amino-3-nitro-4-methyl-5-fluoropyridine is an organic compound. It has a wide range of main uses and is often used as a key intermediate in the synthesis of a variety of specific drugs. Due to the unique chemical structure of this compound, it has the ability to interact with specific targets in organisms. Through carefully designed synthesis routes, drug molecules with specific pharmacological activities, such as antibacterial, antiviral or anti-tumor drugs, can be precisely constructed, making great contributions to human health and well-being.
    In the field of pesticides, it also plays an important role. With its special chemical properties, it can be converted into highly efficient pesticide components through a series of reactions, showing powerful killing or repelling effects on pests, and little damage to crops, which helps to improve crop yield and quality, and ensure food security.
    In the field of materials science, 2-amino-3-nitro-4-methyl-5-fluoropyridine has also emerged. It can be used as a raw material for the synthesis of new functional materials. After ingenious design and polymerization, materials with special electrical, optical or mechanical properties can be prepared, which can be used in many aspects such as electronic devices, optical instruments or high-performance composites, promoting the vigorous development of materials science.
    Furthermore, it is an important building block in the study of organic synthetic chemistry. Chemists can use various functional group transformation and modification reactions to expand the structural diversity of organic molecules, provide rich materials for exploring novel organic reaction mechanisms and synthesis strategies, and then promote the continuous progress of organic chemistry.
    What are 2-Amino-3-nitro-4-methyl-5-fluoropyridine synthesis methods?
    The synthesis method of 2-amino-3-nitro-4-methyl-5-fluoropyridine is an important matter for chemical preparation. In the past, the synthesis of this compound was by multi-cycle method.
    First, the compound containing the pyridine structure was used as the starting material. First, the specific position on the pyridine ring was modified, and the methyl group was introduced at the appropriate check point by substitution reaction. This step requires the selection of suitable methylation reagents, such as iodomethane, dimethyl sulfate, etc., and the introduction of methyl groups can be efficiently achieved under the catalysis of suitable bases.
    Then, the nitration reaction was carried out. The mixed acid system of nitric acid and sulfuric acid is selected to make the nitro group fall precisely at the predetermined position of the pyridine ring at low temperature to obtain the pyridine derivative containing nitro group. This process is very strict in controlling the reaction temperature, and a little negligence can easily lead to a cluster of side reactions, which affect the purity and yield of the product.
    Then fluorine reagents, such as potassium fluoride, are used to introduce fluorine atoms at the designated position of the pyridine ring with the assistance of a phase transfer catalyst. The choice of phase transfer catalyst is related to the reaction rate and efficiency, and quaternary ammonium salts are common.
    Finally, after amination, a specific amine group is introduced into the pyridine ring to obtain 2-amino-3-nitro-4-methyl-5-fluoropyridine. The choice of amination reagent depends on the specific reaction conditions and requirements, either as an alcohol solution of ammonia gas or as a specific organic amine compound.
    Each step of the reaction requires detailed regulation of the reaction conditions, such as temperature, time, and the proportion of reactants, etc., and the intermediate products need to be properly handled during each step. After separation and purification, a high-purity target product 2-amino-3-nitro-4-methyl-5-fluoropyridine can be obtained.
    2-Amino-3-nitro-4-methyl-5-fluoropyridine What are the precautions during storage and transportation?
    2-Amino-3-nitro-4-methyl-5-fluoropyridine is an organic compound. During storage and transportation, many matters need to be paid attention to.
    First storage conditions. This compound should be stored in a cool, dry and well-ventilated place. High temperature and humidity can easily damage its stability, or cause adverse reactions such as decomposition. Keep away from fires and heat sources, as it is exposed to open flames, hot topics or the risk of combustion and explosion.
    Times and packaging. When storing and transporting, the packaging must be tight. A suitable sealed container can be used to prevent leakage. If the package is damaged, the compound will come into contact with air, moisture, etc., or become biodegraded, and the leakage will also pose a hazard to the environment and personnel.
    Furthermore, avoid mixed storage. Do not mix with oxidants, acids, alkalis and other substances. Due to its active chemical nature, contact with the above substances, or severe chemical reaction, resulting in dangerous conditions such as fire, explosion, etc.
    The transportation process is also important. It is necessary to follow relevant regulations and standards and choose qualified transportation tools. During transportation, ensure that the container is not tipped, leaked, or damaged. And transportation personnel need to be professionally trained and familiar with the characteristics of the compound and emergency treatment methods.
    Storage and transportation of 2-amino-3-nitro-4-methyl-5-fluoropyridine requires careful treatment in terms of storage conditions, packaging, co-storage contraindications, and transportation practices to ensure its safety and stability and avoid accidents.
    What is the market outlook for 2-Amino-3-nitro-4-methyl-5-fluoropyridine?
    2-Amino-3-nitro-4-methyl-5-fluoropyridine is an organic compound with unique properties. Looking at its market prospects, it is indeed promising.
    In the field of medicine, due to its unique chemical structure, it has potential biological activity, which may lay the foundation for the creation of new drugs. For example, in the development of antibacterial drugs, its structure can be modified to fit specific bacterial targets, which is expected to open up new antibacterial therapies to deal with the increasingly serious problem of drug-resistant bacteria. And in the exploration of anti-cancer drugs, it may serve as a key intermediate to construct molecules with targeted anti-cancer activity, bringing new hope for cancer treatment.
    In the field of materials science, it has also made a name for itself. With its nitrogen, fluorine and other elemental properties, it may be able to participate in the preparation of high-performance organic optoelectronic materials. If applied to organic Light Emitting Diode (OLED), it can optimize the luminous efficiency and stability, improve the performance of display technology, and help the display screen move towards a clearer and more energy-efficient direction. In the field of sensor materials, because of its specific response to specific substances, high-sensitivity chemical sensors can be developed for the detection of environmental pollutants, biomarkers, etc., providing a powerful tool for environmental monitoring and biomedical diagnosis.
    Furthermore, with the advancement of chemical synthesis technology, its synthesis cost may be gradually reduced, and the output can be increased, further expanding the market application space. Many scientific research institutions and enterprises have invested in related research and development, striving to tap more potential value. With time, 2-amino-3-nitro-4-methyl-5-fluoropyridine will surely shine in many fields and promote the development of various industries.