2-Amino-3-(ethoxycarbonyl)pyridine

2-Amino-3- (ethoxycarbonyl) pyridine, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of pharmaceutical synthesis.
The development of pharmaceutical chemistry and the creation of many drugs rely on this substance. Due to its unique structure, it can participate in a variety of chemical reactions. After modification and transformation, it can build a molecular structure with specific pharmacological activities. For example, in the synthesis of some antimalarial drugs, 2-amino-3- (ethoxycarbonyl) pyridine plays an important role in it, helping to build the core skeleton of the drug, which in turn gives the drug the effect of fighting malaria parasites.
In the field of materials science, it also has its application. Or it can be introduced into polymer materials through specific reactions to change the properties of materials. For example, to improve the optical properties of materials, making them stand out in the field of optoelectronic devices; or to enhance the stability and durability of materials for material preparation in special environments.
Furthermore, in organic synthetic chemistry, it provides the possibility for the synthesis of complex organic molecules. With the reactivity of its functional groups, it can react with many reagents such as nucleophilic substitution and electrophilic addition, opening up new paths for organic synthetic chemists to prepare novel and potentially valuable compounds.
To sum up, 2-amino-3- (ethoxycarbonyl) pyridine plays an important role in many fields such as medicine, materials and organic synthesis due to its unique structure and reactivity. It is an indispensable substance in the field of organic chemistry.

To prepare 2-amino-3- (ethoxycarbonyl) pyridine, there are various methods. First, it can be started from a suitable pyridine derivative. First, take the pyridine containing the suitable substituent, and use it as the base. After delicate transformation, the purpose of preparing the target is achieved. For example, with an active substituent pyridine, under suitable reagents and conditions, nucleophilic substitution or electrophilic substitution reaction is carried out to gradually introduce ethoxycarbonyl and amino groups.
Second, by using the cyclization reaction commonly used in organic synthesis. Select a chain compound containing a specific functional group, make it cyclized under appropriate catalysts, temperatures and reaction environments, and construct a pyridine ring, and introduce the desired ethoxycarbonyl and amino groups at the same time. This requires subtle control of the functional group activity and reaction conditions of the reactants in order to obtain the target product.
Third, the metal catalytic coupling reaction is used as the diameter. Select a specific halogenated or borate-substituted pyridine derivative, and a reagent containing ethoxycarbonyl or amino group, under the action of a metal catalyst, such as palladium, copper and other catalytic systems, coupling occurs. Precise preparation of catalysts, ligands and reaction conditions makes the reaction efficient and selective to generate 2-amino-3- (ethoxycarbonyl) pyridine. Each method has its own advantages and disadvantages, and it is necessary to weigh the selection according to the actual situation, such as the availability of raw materials, cost, difficulty of reaction, product purity, etc., and carefully design the experimental steps to prepare the target product.

2-Amino-3- (ethoxycarbonyl) pyridine is an important compound in organic chemistry. Its physical properties are unique and it has many applications in scientific research and industrial fields.
This compound is a solid under normal conditions, but due to the characteristics of the amino and ethoxycarbonyl groups it contains, its melting point and boiling point are slightly different from those of ordinary organic compounds. It has been determined by many experiments that its melting point is about [X] ° C, which is of great significance for the separation and purification of the compound. When the temperature rises to the boiling point, about [X] ° C, the substance is converted from a liquid state to a gaseous state, and this process can be used for the separation or purification of the compound by distillation.
In terms of solubility, 2-amino-3- (ethoxycarbonyl) pyridine exhibits unique properties. Due to the hydrophilicity of amino groups and the lipophilicity of ethoxycarbonyl groups, it has a certain solubility in water and can also be soluble in some organic solvents, such as ethanol and acetone. In ethanol, the compound can be uniformly dispersed by virtue of the intermolecular force between the two, and the solubility is considerable; in acetone, a similar situation is also present. This solubility characteristic makes it possible to choose a suitable solvent according to the needs in different chemical reactions and preparation processes to promote the reaction or achieve product separation.
Furthermore, the appearance of the compound is often white to light yellow crystalline powder. This appearance feature not only provides the basis for preliminary identification, but also reflects its internal crystal structure and molecular arrangement. White to light yellow color, or due to the influence of intra-molecular electron transition and conjugate system, the absorption and reflection of specific wavelengths of light.
The physical properties of 2-amino-3- (ethoxycarbonyl) pyridine, from melting point, boiling point to solubility, to appearance, lay the foundation for its application in the field of chemistry. Scientists can design more delicate chemical reactions based on these properties to achieve efficient synthesis and separation of products; in industrial production, the process can also be optimized accordingly to improve production efficiency and product quality.

The stability of the chemical properties of 2-amino-3- (ethoxycarbonyl) pyridine depends on many factors. The structure of this compound is that the amino group and ethoxycarbonyl group are combined on the pyridine ring. The pyridine ring is aromatic and has a relatively stable structure, which can endow the compound with certain stability.
The amino group has the property of electron donor, which can increase the electron cloud density of the pyridine ring by means of conjugation effect, which may affect its activity and stability in some reactions. However, the amino group also has certain nucleophilicity. Under appropriate conditions, it may react with electrophilic reagents to change the structure of the compound, which will damage its stability.
As for the ethoxycarbonyl group, it is an electron-withdrawing group, which can reduce the electron cloud density of the pyridine ring through induction effects. In this way, the electron-giving effect of the amino group antagonizes each other, and the interaction between the two may maintain the relative stability of the compound structure to a certain extent. However, under conditions such as alkaline conditions, ethoxycarbonyl may undergo hydrolysis to form carboxyl groups and ethanol, which will also lead to structural changes and reduced stability of the compound.
Furthermore, external conditions such as temperature, light, and solvents also have a significant impact on its stability. Under high temperature, the thermal motion of molecules intensifies, and chemical reactions are more likely to occur, or cause compounds to decompose. If light can initiate photochemical reactions, it will also change its chemical structure. Different solvents may affect their reactivity and stability due to their different solubility and interaction with compounds.
In summary, the stability of 2-amino-3- (ethoxycarbonyl) pyridine cannot be generalized, depending on the specific environment and conditions. In a specific environment, it may remain relatively stable, while under certain conditions, chemical reactions may occur, and the stability is poor.

I look at your question, but I am inquiring about the price range of 2-amino-3- (ethoxycarbonyl) pyridine on the market. However, the price of this compound is difficult to determine, and there are three reasons.
First, the supply and demand situation in the market often affects its price. If there are many applicants and few suppliers, the price will tend to increase; if the supply exceeds the demand, the price may trend down.
Second, the purity of the product is also the key. High purity, difficult to prepare, high cost, and high price; low purity, easy to prepare, low cost, and low price.
Third, different suppliers have different pricing. < Br >
According to the past market, if it is ordinary purity, the quantity is small (gram level), or tens of yuan per gram; if the quantity is increased (hundred gram level, kilogram level), the price per gram may be reduced to a few yuan to more than ten yuan. If you want high purity (such as more than 99%), the gram level price may exceed 100 yuan.
However, the market is ever-changing and the price fluctuates. For accurate prices, you can consult chemical raw material suppliers or check in detail on the chemical product trading platform to get the current exact price range.