2 Amino 3 Cyano 6 Methylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-3-cyano-6-methylpyridine

    Specifications

    HS Code

    106998

    Chemical Formula C7H7N3
    Molar Mass 133.15 g/mol
    Appearance Solid (likely white or off - white powder)
    Physical State At Room Temperature Solid
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, methanol
    Melting Point 175 - 179 °C (approximate, may vary)
    Boiling Point Decomposes before boiling
    Pka Value Relevant acidic/basic groups would have characteristic pKa values, but specific values depend on the context of the medium
    Odor Odorless or faint odor
    Stability Stable under normal conditions, but sensitive to strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Amino-3-cyano-6-methylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Amino-3-cyano-6-methylpyridine?
    2-Amino-3-cyano-6-methylpyridine is an organic compound that is useful in many fields. Its primary use is in pharmaceutical synthesis. Due to its unique chemical structure, this compound can be used as a key intermediate to prepare a variety of biologically active drugs. For example, by combining specific chemical reactions with other reagents, drug molecules that target specific diseases can be created, which has great potential for the treatment of diseases.
    In the field of pesticides, 2-amino-3-cyano-6-methylpyridine has also been used. It can be used as an important raw material for synthetic pesticides. After rational design and reaction, pesticide products with high insecticidal, bactericidal or herbicidal properties can be obtained. These pesticides can effectively protect crops from pests and diseases, improve crop yield and quality, and ensure a bumper harvest in agriculture.
    Furthermore, in the field of materials science, it has also made a name for itself. It can participate in the synthesis of functional materials and endow materials with specific physical or chemical properties. For example, the introduction of appropriate reactions into polymer systems may improve the electrical, optical or mechanical properties of materials, opening up new paths for the research and development of new materials.
    In summary, 2-amino-3-cyano-6-methylpyridine, due to its unique structure, plays an important role in the fields of medicine, pesticides, and materials science, providing key assistance for the development of related industries. It is of great value in modern chemical industry and scientific research.
    What are the physical properties of 2-Amino-3-cyano-6-methylpyridine?
    2-Amino-3-cyano-6-methylpyridine is an important compound in organic chemistry. Its physical properties are unique and of great significance to chemical research and industrial applications.
    Looking at its properties, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This form is easy to store and use, and is easy to operate in many chemical reactions.
    When it comes to the melting point, it is about 148-152 ° C. The characteristics of the melting point can help chemists identify the purity of the compound. If the purity is high, the melting point range is narrow and approaches the standard value; if it contains impurities, the melting point will decrease and the range will become wider. This property plays a key role in the purification and quality control of compounds.
    In terms of solubility, the substance is slightly soluble in water, but easily soluble in common organic solvents, such as ethanol, dichloromethane, N, N-dimethylformamide, etc. This difference in solubility is due to the fact that its molecular structure includes both polar groups such as amino and cyano, and relatively non-polar parts such as methyl and pyridine rings. Slightly soluble in water, due to the limited matching of the polarity of water molecules with the overall polarity of the compound; while the polarity of organic solvents is similar to the partial structure of the compound, or can form intermolecular forces with polar groups, so the solubility is good. This solubility characteristic has a great impact on the choice of solvents in chemical reactions. Suitable solvents can promote the smooth progress of the reaction, improve the reaction efficiency and product purity.
    In addition, 2-amino-3-cyano-6-methylpyridine also has certain stability, but under certain conditions, such as strong acid, strong alkali environment, or extreme conditions such as high temperature and high humidity, the structure will change, participate in chemical reactions, and generate new compounds. Chemists need to properly store and reasonably design reaction conditions according to its stability characteristics to ensure that the properties of the compound are controllable and serve the intended chemical purpose.
    2-Amino-3-cyano-6-methylpyridine chemical synthesis methods
    The chemical synthesis method of 2-amino-3-cyano-6-methylpyridine covers several pathways. First, it can be started from a suitable pyridine derivative and formed by a specific substitution reaction. For example, select a pyridine parent body, which has a substitutable group in its structure, and use an amination reagent, such as an active compound containing an amino group, to replace the atom or group at a specific position on the pyridine ring under suitable reaction conditions, and then introduce an amino group. At the same time, another reagent containing a cyanide group is selected, and the cyanide group is connected to the corresponding check point of the pyridine ring through cyanidation. The methyl group, either already present in the starting material, or can be introduced at an appropriate stage by methylating reagents.
    Second, it can be achieved by the strategy of constructing a pyridine ring. Using a few simple organic small molecules as raw materials, the cyclization reaction forms a pyridine ring structure. For example, small molecules containing nitrogen and carbon, under the conditions of catalyst, suitable temperature and reaction medium, cyclization condensation reaction occurs to construct a pyridine ring. During the reaction process, the reaction steps and reagent selection are cleverly designed, so that the amino group, cyano group and methyl are precisely connected to the predetermined position when the pyridine ring is formed, or in subsequent steps.
    Furthermore, the existing synthesis ideas of similar compounds in the literature can be referred to to to be optimized. Examine the relevant synthesis routes, consider the reaction conditions, yield, selectivity and other factors, and make targeted adjustments to the reagents used, reaction sequence, reaction conditions, etc., to be suitable for the synthesis of 2-amino-3-cyano-6-methyl pyridine, and strive to obtain the target product efficiently and with high purity.
    2-Amino-3-cyano-6-methylpyridine What are the precautions during storage and transportation?
    2-Amino-3-cyano-6-methylpyridine is an organic compound. When storing and transporting, the following matters must be paid attention to:
    First, the storage environment is the most critical. This compound should be stored in a cool, dry and well-ventilated place. It can be damaged due to humid environment or moisture and deterioration, and high temperature may cause chemical reactions and damage quality. If it is hot in summer, the warehouse temperature should be strictly controlled to prevent its properties from changing. And it should be kept away from fire and heat sources. Because of its flammability, it is easy to cause fire if an open flame is close.
    Second, the packaging must be tight. Use a well-sealed packaging container to avoid contact with air. Due to the reaction of some groups or with oxygen, moisture, etc. in the air. For example, the cyanyl group undergoes hydrolysis reaction with water under specific conditions, so the packaging is tight to ensure its stability.
    Third, during transportation, make sure that the container does not leak, collapse, fall, or damage. It should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. Due to the active chemical properties of this compound, contact with the above substances or cause violent chemical reactions, endangering transportation safety.
    Fourth, operators need to be specially trained and strictly abide by the operating procedures. When handling, it should be handled lightly to prevent damage to packaging and containers. If the package is damaged during operation, emergency measures should be taken immediately, such as rapid cleaning of the spill to prevent its spread and cause greater harm.
    In conclusion, when storing and transporting 2-amino-3-cyano-6-methylpyridine, care must be taken in terms of the environment, packaging, transportation methods, and personnel handling to ensure the safety and quality of the compound.
    2-Amino-3-cyano-6-methylpyridine impact on the environment and human health
    2-Amino-3-cyano-6-methylpyridine has many effects on the environment and human health, which cannot be ignored.
    First talk about its impact on the environment. If this substance flows into natural water bodies, or due to its own chemical properties, it causes water pollution, and aquatic organisms bear the brunt. It may interfere with the physiological metabolism of aquatic organisms, causing their growth and reproduction to be hindered. Such as fish larvae, or due to the presence of this substance in water bodies, abnormal development, body shape aberration, and damage to the nervous system, resulting in disordered behavior, foraging and avoiding enemies are affected, and the population is gradually decreasing. In the soil environment, if contaminated with this substance, or change the structure and function of soil microbial community. The activity of beneficial microorganisms may be inhibited, the circulation of soil nutrients will be blocked, and plant growth will be affected. After the plant root system absorbs this substance, it may affect its own metabolism, and the leaf color will be abnormal, and the yield and quality will decrease.
    As for the impact on human health, it should not be underestimated. If people breathe, contact with the skin or accidentally eat the substances containing this substance, the harm will be born. Inhaled through the respiratory tract, this substance may irritate the mucosa of the respiratory tract, causing cough, asthma and other diseases. Long-term exposure will damage lung function and cause chronic respiratory diseases. Those who come into contact with the skin may show allergies, redness, swelling, itching, and ulceration in severe cases. Accidentally ingested can harm the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, and even damage important organs such as liver and kidney. This substance may be potentially carcinogenic, and long-term low-dose exposure may increase the risk of cancer and endanger life.
    In summary, 2-amino-3-cyano-6-methylpyridine has adverse effects on the environment and human health. When daily production and use, it should be handled with caution to prevent the spread of harm.