2-AMINO-3,5 DIBROMO-4-METHYL PYRIDINE

2-Amino-3,5-dibromo-4-methylpyridine. The physical properties of this substance are listed below.
Its appearance is often white to light yellow crystalline powder, and it maintains a stable solid state at room temperature and pressure. Looking at its color, the characterization of white to light yellow can be one of the aids in identifying this substance.
In terms of melting point, it usually falls within a specific temperature range. This melting point is an inherent characteristic of the substance and is of great significance for the identification and purification of this compound. Accurate determination of its melting point can provide a key basis for confirming its purity and chemical structure.
Solubility is also one of the important physical properties. In organic solvents, such as common ethanol, acetone, etc., the compound exhibits a certain solubility. This property has a significant impact on the reaction process of organic synthesis. Appropriate solvent selection can promote the reaction, improve the yield and purity of the product. In water, its solubility is relatively limited, and this difference reflects the interaction between the molecular structure of the compound and water molecules.
Although there is no extreme particularity in terms of density, its value is indispensable for accurate measurement and the study of material distribution in a specific system. Knowing its density can ensure that the proportion of each substance is accurate when conducting quantitative experiments and designing related processes, so as to achieve the expected experimental or production goals.
The physical properties of this substance play a key role in chemical synthesis, analysis and identification, and practical applications in related fields. According to its characteristics, researchers can rationally plan experimental steps and technological processes.

2-Amino-3,5-dibromo-4-methylpyridine, this is an organic compound. Its chemical properties are unique and of great research value.
First of all, its alkalinity, due to the existence of amino groups, this compound has a certain alkalinity. The nitrogen atom in the amino group contains lone pairs of electrons, which can be combined with protons, and is easy to accept protons in an acidic environment and is alkaline.
Furthermore, its halogenated group characteristics. The bromine atom at position 3,5 is active and can participate in many nucleophilic substitution reactions. The bromine atom has a certain electronegativity, which makes the connected carbon atoms partially positively charged and easily attacked by nucleophiles. Nucleophiles can replace bromine atoms to form new compounds, which are widely used in the field of organic synthesis.
And because of the conjugate system of the pyridine ring, the compound has certain stability. The conjugate system can disperse the electron cloud and reduce the energy of the molecule. At the same time, this conjugate system also affects the reactivity of the molecule, making it possible to undergo electrophilic substitution reactions under specific conditions. On the pyridine ring, due to the positioning effect of methyl and amino groups, electrophilic substitution reactions often occur at specific locations.
In addition, although the methyl group at the 4 position is relatively stable, it can also be oxidized under strong oxidation conditions. Methyl groups can be gradually oxidized to other functional groups such as carboxyl groups, thereby changing the properties and uses of the compound. The chemical properties of 2-amino-3,5-dibromo-4-methylpyridine are rich and diverse, and it has potential applications in many fields such as organic synthesis and pharmaceutical chemistry. It can be used as an important intermediate to participate in various chemical reactions and build more complex organic molecular structures.

The common synthesis method of 2-amino-3,5-dibromo-4-methylpyridine is a multi-step reaction. In the first step, 4-methylpyridine is often used as the starting material, because the pyridine ring has a specific electron cloud distribution, which is favorable for subsequent reactions. First, 4-methylpyridine is brominated. This step requires the selection of appropriate brominating reagents, such as liquid bromine or N-bromosuccinimide (NBS), and the reaction conditions are controlled. Taking liquid bromide as an example, in the presence of suitable catalysts such as iron powder or iron tribromide, liquid bromide reacts with 4-methylpyridine in a specific temperature and solvent, and bromine atoms selectively replace hydrogen atoms at positions 3,5 on the pyridine ring to generate 3,5-dibromo-4-methylpyridine. In this reaction, temperature, solvent and catalyst dosage are all critical, and too high or too low temperature, and improper dosage can cause increased side reactions or incomplete reactions.
Then, 3,5-dibromo-4-methylpyridine is converted into 2-amino-3,5-dibromo-4-methylpyridine. The common method is to undergo diazotization reaction and aminolysis reaction. First, 3,5-dibromo-4-methyl pyridine is diazotized with sodium nitrite under acidic conditions to form a diazonium salt intermediate. This step requires strict reaction temperature and acid concentration, and generally requires low temperature (0-5 ° C) operation to prevent the decomposition of diazonium salts. Subsequently, the diazonium salt undergoes aminolysis with ammonia or ammonia derivatives, and the diazonium group is replaced by an amino group to obtain the target product 2-amino-3,5-dibromo-4-methylpyridine. < Br >
Another synthesis path is to use pyridine derivatives containing suitable substituents as raw materials, and gradually introduce amino groups, bromine atoms and methyl groups through multi-step functional group conversion reactions to achieve the purpose of synthesis. However, the method using 4-methylpyridine as the starting material is more commonly used, because the raw materials are easy to obtain, the reaction steps are relatively clear, and the total yield is also considerable.

2-Amino-3,5-dibromo-4-methylpyridine is used in many fields. In the field of pharmaceutical creation, it is often a key raw material to help synthesize specific drugs. Due to the unique chemical structure of this pyridine derivative, it can interact with specific targets in organisms, or can be used to develop antibacterial, antiviral and even anti-cancer drugs. With its structure and activity, it lays the foundation for the birth of new drugs.
In the field of materials science, it also has its traces. It can be used as a basic component for the construction of special functional materials. After specific chemical reactions, it can be introduced into polymer materials, giving materials such as unique optical and electrical properties. It is expected to be used in the manufacture of optoelectronic devices, such as Light Emitting Diodes, sensors, etc., to achieve precise regulation of material properties through its structural properties.
Furthermore, in the field of organic synthetic chemistry, it is an important intermediate. Organic chemists can use various chemical modifications and transformations to construct more complex and diverse organic compounds, expand the territory of organic synthesis, and provide rich options for the creation of new compounds, thereby promoting the development of organic chemistry and playing an indispensable role in the synthesis of many fine chemicals.

2-Amino-3,5-dibromo-4-methylpyridine, the market price range of this product, it is difficult to say directly. According to Guanfu's "Tiangong Kaiwu", the price of any product often depends on many factors.
First, the abundance of raw materials is related to its price. If the raw materials used to synthesize this pyridine are easy to obtain and abundant in the market, the price may be stable and flat; if the raw materials are rare, they need to be sent far away, or they are subject to various changes in time and personnel, and their sources are scarce, the price must be high.
Second, the difficulty of making methods is also the key. If the preparation method is simple, convenient to handle, and consumes less manpower, material resources, and financial resources, the price will not be high; if the method is very difficult, requires delicate instruments, rare reagents, takes a long time, and the yield is low, the price should be high.
Furthermore, the supply and demand of the market determine its price. If many industry players compete for this product, which is used in the fields of medicine and chemical industry, the demand is greater than the supply, and the price will rise; if there are few requests, the supply will exceed the demand, and the price may drop.
In addition, regional differences also affect the price. In the prosperous city of Dayi, where trade is convergent, transportation is convenient, and logistics costs are low, its price may be relatively easy; in remote places, transportation is difficult, costs increase, and prices rise accordingly.
Overall, the market price of 2-amino-3,5-dibromo-4-methylpyridine, or due to the above reasons, fluctuates in a large range, ranging from a few gold to dozens or hundreds of gold per unit. It is difficult to determine the exact price range.