2 Acetamido 5 Aminopyridine
pyridine pyrrole pyrazine piperidine piperazine

2-Acetamido-5-aminopyridine

    Specifications

    HS Code

    448861

    Chemical Formula C7H9N3O
    Molar Mass 151.166 g/mol
    Appearance Solid (likely white or off - white powder)
    Melting Point Data may vary, typically needs to be experimentally determined
    Solubility In Water Moderate to low solubility, as it has polar and non - polar regions
    Solubility In Organic Solvents Soluble in some polar organic solvents like ethanol
    Pka Value Relevant acidic or basic groups may have pKa values for acid - base equilibria, specific values need experimental determination
    Density Data may vary, needs experimental determination
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Acetamido-5-aminopyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Acetamido-5-aminopyridine?
    2-Acetamido-5-aminopyridine, this is an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. Due to its specific chemical structure and activity, it can participate in various reactions and help build complex molecular structures with biological activity. It plays an important role in the creation of antibacterial, antiviral and anti-tumor drugs.
    In the field of materials science, it may be used to prepare functional materials. By reacting or modifying with other substances, it can endow materials with unique properties, such as optical and electrical properties, providing the possibility for the development of new functional materials.
    Furthermore, in the field of organic synthesis, as an important starting material or intermediate, it can derive many organic compounds with different structures through a series of chemical reactions, enrich the variety of organic compounds, promote the development of organic synthesis chemistry, and lay the foundation for exploring new chemical synthesis paths and methods. In short, 2-acetamido-5-aminopyridine plays an indispensable role in many fields and is of great significance to the progress and development of related fields.
    What are 2-Acetamido-5-aminopyridine synthesis methods?
    2-Acetamido-5-aminopyridine can be synthesized by many methods. One of the methods is to start with 2-amino-5-nitropyridine. Take 2-amino-5-nitropyridine first, place it in a suitable reaction vessel, use acetic anhydride as the acetylation reagent, and carry out the acetylation reaction under the action of appropriate temperature and catalyst. In this process, the acetyl group of acetic anhydride replaces the hydrogen atom on the 2-amino-5-nitropyridine amino group to form 2-acetamido-5-nitropyridine.
    Then, 2-acetamido-5-nitropyridine is placed in another reaction system, and the nitro group is reduced in an acidic medium with suitable reducing agents, such as iron powder, zinc powder, etc. During the reaction, the nitro group is gradually converted into an amino group, and then 2-acetamido-5-aminopyridine is obtained.
    Another method can be started from 2-chloro-5-nitropyridine. First, 2-chloro-5-nitropyridine is reacted with acetamide under strong alkali catalysis, and the chlorine atom is replaced by acetamide group to form 2-acetamido-5-nitropyridine. Subsequent to the reduction method, the nitro group is converted into an amino group, and the final target product is obtained.
    Furthermore, 5-aminopyridine is used as a raw material. First, 5-aminopyridine is reacted with an acetylating agent, such as acetyl chloride or acetic anhydride. Under suitable conditions, the amino group is acetylated to obtain 2-acetamido-5-aminopyridine. < Br >
    This number method has its own advantages and disadvantages. In actual synthesis, it is necessary to choose carefully according to the availability of raw materials, the difficulty of reaction, and the consideration of cost.
    What are the physical properties of 2-Acetamido-5-aminopyridine?
    2-Acetamido-5-aminopyridine is an important compound in organic chemistry. Looking at its physical properties, this substance is mostly in solid form at room temperature, and it has certain stability due to specific forces between molecules. Its melting point is quite critical, because the melting point can reflect the degree of bonding between molecules. After many experiments, it can be seen that its melting point is within a certain range, which is an important indicator to define the purity and characteristics of the substance.
    Furthermore, when it comes to solubility, 2-acetamido-5-aminopyridine behaves differently in different solvents. In polar solvents, there is a certain solubility due to the interaction between molecules and solvents, such as hydrogen bonds. However, in non-polar solvents, the solubility is significantly reduced due to the large difference in the intermolecular forces between the two molecules. This solubility characteristic has crucial applications in the process of chemical synthesis and separation and purification.
    In addition, the color state of the compound is also worthy of attention. Pure 2-acetamido-5-aminopyridine often has a specific color, either white or slightly yellowish. This color state characteristic can not only be used as a basis for preliminary identification of the substance, but also reflects its purity to a certain extent. In conclusion, the physical properties of 2-acetamido-5-aminopyridine, such as melting point, solubility, color state, etc., are the basis for the in-depth understanding and application of this compound.
    2-Acetamido-5-aminopyridine What are the precautions during storage and transportation?
    2-Acetamido-5-aminopyridine is an important organic compound. When storing and transporting, the following numbers should be paid attention to:
    First, the storage environment is the key. This compound should be stored in a cool, dry and well-ventilated place. If the environment is humid, it is easy to cause it to be damp and deteriorate, and the product quality will be damaged due to moisture or chemical reactions. Excessive temperature is not suitable. Excessive temperature may accelerate its decomposition or cause other adverse reactions, so it is necessary to maintain the appropriate temperature. Generally speaking, normal temperature or slightly lower temperature is more suitable.
    Second, the packaging must be tight. Appropriate packaging materials should be selected, such as containers with excellent sealing performance, to prevent contact with air, moisture, etc. If the packaging is not strict, components such as oxygen or carbon dioxide in the air may react with the compound, causing its properties to change.
    Third, during transportation, avoid violent vibration and collision. 2-Acetamido-5-aminopyridine may have certain sensitivity, strong vibration and collision may cause its physical state to change, or even cause chemical reactions, endangering transportation safety and product quality.
    Fourth, pay attention to isolation from other substances. This compound should not be mixed or mixed with oxidizing substances, acidic substances or alkaline substances, etc., because these substances or chemical reactions with them, or cause danger such as combustion, explosion, or reduce product quality.
    Fifth, the storage and transportation site should be equipped with corresponding safety facilities and emergency treatment equipment. Such as fire extinguishing equipment, leakage emergency treatment tools, etc., so that in the event of an emergency, it can respond quickly and effectively to reduce losses and hazards.
    In short, for the storage and transportation of 2-acetamido-5-aminopyridine, it is necessary to comprehensively consider many factors such as environment, packaging, vibration and relationship with other substances to ensure its quality and safety.
    What is the market outlook for 2-Acetamido-5-aminopyridine?
    2-Acetamido-5-aminopyridine is an interesting topic in today's market prospects.
    Looking back at the past, the development of chemical products is changing with each passing day, and many new compounds have emerged, including 2-acetamido-5-aminopyridine. It has attracted much attention in the field of medicinal chemistry. Because of its unique structure or potential biological activity, it can be used as a key intermediate for drug development.
    In the drug synthesis path, 2-acetamido-5-aminopyridine can be combined with other chemical groups through specific reactions to form drug molecules with specific pharmacological functions. With the surge in demand for innovative drugs in the pharmaceutical industry, the demand for such key intermediates is also on the rise.
    Furthermore, in the field of materials science, it may also have applications. Because the amino and acetamido groups contained in itself may endow materials with certain special physical and chemical properties, such as improving the solubility and stability of materials, it may play an important role in the preparation of new materials.
    However, although the market prospect is good, there are also challenges. The process of synthesizing this compound needs to be continuously optimized to increase yield and reduce costs. And it needs to follow increasingly strict environmental regulations to ensure that the production process is green and sustainable.
    In summary, 2-acetamido-5-aminopyridine has broad market prospects in the fields of medicine and materials. However, in order to fully tap its potential, it is still necessary for industry professionals to make unremitting research and efforts in synthetic processes and environmentally friendly production.