2 6 Pyridinediamine 4 Bromo
pyridine pyrrole pyrazine piperidine piperazine

2,6-Pyridinediamine, 4-bromo-

    Specifications

    HS Code

    224499

    Chemical Formula C5H6BrN3
    Molecular Weight 186.026
    Appearance Solid
    Color Typically white to off - white
    Odor May have a faint, characteristic amine - like odor
    Melting Point Data may vary, but typically in a certain range (needs specific experimental determination)
    Boiling Point Requires experimental determination
    Solubility Soluble in some polar organic solvents like ethanol, less soluble in non - polar solvents
    Density Needs experimental measurement
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Hazard May be harmful if swallowed, inhaled or in contact with skin

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    General Information
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    Frequently Asked Questions

    As a leading 2,6-Pyridinediamine, 4-bromo- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2,6-Pyridinediamine, 4-bromo-?
    2% 2C6 - Pyridinediamine% 2C + 4 - bromo - that is, 4 - bromo - 2,6 - pyridinediamine, this is an organic compound. Its chemical properties are unique, let me explain in detail.
    From the structural point of view, the pyridine ring is its core, and the amino and bromine atoms on it give it specific chemical activity. Amino groups have a certain basic nature and can react with acids to form corresponding salts. Under suitable conditions, amino groups can participate in nucleophilic substitution reactions, such as reacting with halogenated hydrocarbons to form new C-N bonds and construct more complex organic structures. The presence of
    bromine atoms is also crucial. It is a good leaving group, which can make the compound participate in many nucleophilic substitution reactions. In basic environment, bromine atoms are easily replaced by nucleophilic reagents to realize the conversion of functional groups. In addition, bromine atoms can also participate in the localization effect of aromatic electrophilic substitution reactions, which affects the regioselectivity of the reaction.
    4-bromo-2,6-pyridine diamine may also exhibit certain coordination ability. Because the nitrogen atom of the pyridine ring and amino group can provide lone pairs of electrons to coordinate with metal ions to form metal complexes, it may have potential applications in catalysis, materials science and other fields. < Br >
    This compound has a significant position in the field of organic synthesis. Due to its unique chemical properties, it provides an important starting material for the construction of various pyridine derivatives and contributes to the development of organic synthetic chemistry.
    What are the main uses of 2,6-Pyridinediamine, 4-bromo-?
    2% 2C6 - Pyridinediamine% 2C 4 - bromo - that is, 4 - bromo - 2,6 - pyridinediamine, which has a wide range of uses.
    In the field of medicinal chemistry, it can be used as a key intermediate to help create a variety of drugs. The structure of geinpyridinediamine is common in many bioactive compounds. The introduction of 4 - bromo substituents can precisely adjust the reactivity and spatial structure of molecules, so as to achieve more compatible interactions with specific biological targets. For example, in the development of antimicrobial drugs, by ingenious modification and derivation of the compound structure, it is expected to develop new antimicrobial agents with high selective inhibitory activity against specific pathogens to deal with the increasingly serious problem of bacterial resistance.
    In the field of materials science, 4-bromo-2,6-pyridinediamine also shows unique value. It can participate in the synthesis process of polymer materials, and by virtue of the amino and bromine atoms it contains, it can connect to the polymer backbone or side chain through chemical reaction, giving the material novel properties. For example, in the preparation of conjugated polymers with special optical or electrical properties, the introduction of this compound can adjust the energy level structure of the polymer and improve its photoelectric conversion efficiency, which has potential applications in organic Light Emitting Diode (OLED), solar cells and other fields.
    In organic synthetic chemistry, it can participate in many organic reactions as a multifunctional reagent. Because of its nucleophilicity of amino groups, bromine atoms have good departure properties and can be used to construct complex organic molecular structures. For example, by undergoing nucleophilic substitution reactions with halogenated aromatics, or participating in transition metal-catalyzed coupling reactions, etc., it expands the diversity of carbon frameworks and functional groups of organic molecules, providing an effective way for the synthesis of organic compounds with specific structures and functions.
    What is the synthesis method of 2,6-Pyridinediamine, 4-bromo-?
    There are currently 2,6-pyridine diamine and 4-bromine, and the synthesis method is as follows.
    Pyridine is first taken as the starting material. Pyridine has an aromatic ring structure and is chemically stable. Appropriate brominating reagents, such as bromine (Br ³), react with pyridine under suitable reaction conditions. This reaction condition needs to be carefully controlled, the temperature should be maintained at a low temperature range, and it can be operated in an ice bath environment. Appropriate catalysts, such as iron powder (Fe) or iron tribromide (FeBr ³), need to be added. Under these conditions, bromine atoms can selectively replace hydrogen atoms at the 4-position on the pyridine ring to generate 4-bromopyridine. < Br >
    After obtaining 4-bromopyridine, react it with an appropriate amination reagent. An alcohol solution of ammonia (NH 🥰) can be selected and reacted in an autoclave. The reaction temperature needs to be raised to a certain extent, between about 100-150 ° C, and the pressure needs to be maintained within a certain range, so that the ammonia molecule can effectively replace the bromine atom to generate the 4-bromo-2,6-diaminopyridine precursor.
    However, at this time, the product or containing impurities needs to go through a fine purification step. The method of recrystallization can be used to select a suitable solvent, such as ethanol-water mixed solvent, and take advantage of the difference in solubility between the product and impurities in the solvent at different temperatures to recrystallize multiple times to obtain a pure 4-bromo-2,6-pyridinediamine.
    In addition, there are other synthesis paths. Pyridine can be aminated first and then brominated. However, attention should be paid to the regulation of the reaction conditions at each step to ensure the selectivity and yield of the reaction. In this way, the synthesis method of 2,6-pyridinediamine and 4-bromine can be obtained.
    2,6-Pyridinediamine, 4-bromo - what are the precautions in storage and transportation
    2% 2C6-pyridinediamine, 4-bromine - When storing and transporting this product, many key things need to be paid attention to.
    First, because of its chemical properties, it is quite sensitive to environmental factors. It should be stored in a dry, cool and well-ventilated place, beware of moisture and high temperature. If it is in a humid environment, it is easy to cause chemical reactions, or deterioration and failure; under high temperature, it may also cause unstable reactions, which will damage its quality and performance.
    Second, when transporting, it is necessary to ensure that the packaging is tight. This compound may be dangerous, and tight packaging can effectively avoid leakage to prevent threats to transporters and the surrounding environment. The packaging material must meet the relevant standards and have sufficient strength and sealing.
    Third, during the handling process, the operator should handle it with care and must not operate it brutally. Due to its special chemical structure, it is subject to violent impact or vibration, or causes unexpected reactions.
    Fourth, whether it is storage or transportation, it is necessary to strictly follow relevant regulations and standards. This compound may be a controlled chemical, and following regulations can ensure legal compliance of the entire process and avoid legal risks. And it should be equipped with corresponding emergency measures. In the event of unexpected situations such as leaks, it can be dealt with quickly and properly to minimize the harm. In this way, the safety and stability of 2% 2C6-pyridinediamine, 4-bromine can be ensured during storage and transportation.
    2,6-Pyridinediamine, 4-bromo - What are the effects on the environment and human health?
    2% 2C6 - Pyridinediamine% 2C 4 - bromo - that is, 4 - bromo - 2,6 - pyridinediamine. The impact of this substance on the environment and human health, although the ancients did not see this substance firsthand, it can be deduced from today's reasons.
    In terms of the environment, if this chemical substance is released in nature, it may disturb the ecological balance. It enters the soil, or affects the reproduction and metabolism of soil microorganisms, causing soil fertility and material cycles to change. Enter the water body, or poison aquatic organisms, from plankton to fish and shrimp, or suffer from it, destroying the food chain structure of aquatic ecosystems.
    As for human health, if people are exposed to this substance through breathing, skin contact or ingestion, there may be many hazards. Respiratory contact, or cause respiratory irritation, such as cough, asthma, breathing difficulties; skin contact, or cause allergies, redness, swelling, itching and other symptoms. If ingested by mistake, it may damage the digestive system, cause nausea, vomiting, abdominal pain, or even affect liver and kidney function. Long-term exposure may cause mutation and cancer.
    To sum up, although the ancient people have not heard of this chemical, it is now scientifically recognized that its potential threat to the environment and human health should not be underestimated, and it should be treated with caution to prevent its improper discharge and exposure.