2 6 Pyridine Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,6-Pyridine carboxylic acid

    Specifications

    HS Code

    899744

    Name 2,6-Pyridine carboxylic acid
    Molecular Formula C7H5NO4
    Molar Mass 167.12 g/mol
    Appearance White to off - white solid
    Odor Odorless
    Melting Point 292 - 296 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF
    Pka1 2.67
    Pka2 5.57
    Acidic Nature Diprotic acid
    Crystal Structure Monoclinic (reported in some studies)

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    General Information
    Where to Buy 2,6-Pyridine carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 2,6-Pyridine carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-pyridinedicarboxylic acid?
    2% 2C6-diacid was widely used in ancient times, and its main uses are quite extensive.
    In the field of medicine, the ancients found that 2% 2C6-diacid has certain medicinal effects. In case of some surface sores, the drug containing this acid is applied to the affected area, which can help reduce swelling and pain, and promote wound healing. Therefore, the acid has a certain ability to sterilize and reduce inflammation, which can prevent further infection of the sore area and accelerate the recovery of the body.
    In the field of dyeing, 2% 2C6-diacid also plays an important role. It was often used as a mordant in ancient dyeing workshops to help dyes adhere better to fabrics. Taking silk dyeing as an example, dipping silk in a solution containing 2% 2C6-diacid and then cooking it with the dye can make the dyed color more vivid and firm, and it will not fade for a long time. This is because it can chemically react with the dye to form a more stable structure and enhance the bonding force between the dye and the fabric fiber.
    Furthermore, in some processes, 2% 2C6-diacid is also indispensable. For example, when making paper of a specific texture, adding an appropriate amount of this acid can improve the flexibility and durability of the paper. The principle is that this acid can interact with the paper fibers, fill the gaps between the fibers, and make the paper structure tighter, thereby improving its quality and prolonging its service life.
    What are the physical properties of 2,6-pyridinedicarboxylic acid?
    2,6-Dimethylbenzoic acid is an organic compound with the following physical properties:
    Its appearance is white to light yellow crystalline powder. It exists stably at room temperature and pressure. The melting point is about 140-143 ° C. At this temperature, the substance changes from solid to liquid. The boiling point is about 288 ° C. When the temperature rises to the boiling point, the substance changes from liquid to gaseous.
    2,6-Dimethylbenzoic acid is slightly soluble in water. Because water is a polar molecule, while 2,6-Dimethylbenzoic acid molecules have weak polarity. According to the principle of "similar miscibility", its solubility in water is low. However, it is soluble in organic solvents such as ethanol, ether, and chloroform, because these organic solvents are similar to their intermolecular forces and can be miscible with each other.
    This substance has a certain odor. Although it is not a foul odor and pungent smell, it has its own unique smell. This smell is derived from the interaction of benzene ring and methyl groups in its molecular structure. And 2,6-dimethylbenzoic acid has a slightly higher density than water. When participating in some processes involving phase separation or mixing, it will be in a specific position due to its density characteristics. Under common conditions, 2,6-dimethylbenzoic acid is solid, and it is relatively convenient to store and transport. It is only necessary to avoid extreme environments such as high temperature and humidity to prevent its physical state from changing or chemical reactions.
    Is the chemical properties of 2,6-pyridinedicarboxylic acid stable?
    2% 2C6 - to its dicarboxylic acid (2,6 - naphthalic acid), this material is stable. Its properties are firm and resistant, and it has good resistance to heat and agents.
    Looking at its heated state, it has hot topic stability. To make it melt, it needs to be heated to more than 300 degrees. Under such a hot topic, its shape gradually changes, and it is self-solidifying and liquid. This property is beneficial for many high temperature processes, and it can ensure that the material does not lose its shape in high temperature environments. Many engineering plastics often rely on this.
    Let's talk about its chemical resistance again. In case of common acid-base reagents, 2,6-naphthalic acid is stable. In acid, such as dilute sulfuric acid and hydrochloric acid, it can sit still and not react, insoluble and insoluble, and the shape and quality are the same as before; in alkali, such as sodium hydroxide solution, it is also safe and unresponsive. This characteristic makes it widely used in many fields of chemical and pharmaceutical industry. It can be used as a container, pipeline material to hold acid and alkali and other chemicals to ensure the stability of its chemical process.
    And because of its molecular structure, it has good oxidation resistance. In the air, after years, it is not easy to be eroded by oxygen. This shows its superiority in outdoor materials. It can still maintain its properties after sun and rain, and the color and strength are not easy to change. For example, outdoor building decoration materials can be used for a long time and are always new. < Br >
    Overall, 2,6-naphthalic acid has stable properties, good thermal and chemical resistance, and strong oxidation resistance. It is widely used in industrial production and material preparation. It is an important and excellent compound.
    What are the synthesis methods of 2,6-pyridinedicarboxylic acid?
    2% 2C6-glutaric acid, also known as sorbic acid, has many synthesis methods, which are described in detail below.
    First, butenaldehyde and malonic acid are used as raw materials. Under the catalysis of pyridine, the condensation reaction of the two occurs to generate 2% 2C6-glutaric acid. This reaction is mild, the conditions are easy to control, and the raw materials are relatively common. The reaction mechanism is that malonic acid under the action of pyridine, the carboxyl activity is enhanced, and the nucleophilic addition occurs with the double bond of butenaldehyde, and then dehydrated and condensed to obtain the target product.
    Second, crotonaldehyde and diethyl oxalate are used as starting materials. First, under the catalysis of sodium alcohol, the two condensed to form an intermediate, and then the intermediate was hydrolyzed and decarboxylated to obtain 2% 2C6-glutenedioic acid. This path step is slightly complicated, but the source of raw materials is extensive and the cost is controllable. During condensation, sodium alcohol activates the α-hydrogen of diethyl oxalate and adds double bonds with crotonaldehyde; in the stage of hydrolysis and decarboxylation, under acidic conditions, ester groups are hydrolyzed to carboxyl groups, and then decarboxylated to obtain the target.
    Third, vinyl acetylene, carbon monoxide and water are used as raw materials. In the presence of a specific catalyst, a carbonylation reaction occurs to generate 2% 2C6-glutenedioic acid. This reaction has high atomic utilization and conforms to the concept of green chemistry. During the reaction, the catalyst activates vinyl acetylene, and carbon monoxide and water participate in the reaction to build the skeleton of glutaric acid.
    The above synthesis methods have their own advantages and disadvantages, and the practical application needs to be carefully selected according to factors such as raw material availability, cost, and product purity.
    What is the price range of 2,6-pyridinedicarboxylic acid in the market?
    2% 2C6 - The price of the diacid in the market is uncertain. The price of the cover often changes due to changes in time, place, and supply and demand. However, you can consider the market conditions and know the price of the domain.
    Looking at the books of various commercial affairs and the reports of Jia Ren, 2% 2C6 - The price of the diacid in the market is often around 100 yuan per kilogram. If the market is abundant and the demand is limited, the price may be reduced to 80 yuan per kilogram; if the supply is less and the demand is more, the price may rise to one hundred and twenty yuan per kilogram.
    Also, its price is also dependent on quality. Those with high quality are often higher than ordinary products. The refined 2% 2C6 - diacid may reach one hundred and fifty yuan per kilogram, and the lesser one, or only seventy or eighty yuan per kilogram.
    And the origin and shipping route also affect its price. If it is shipped from a distance, the price may be slightly higher due to the additional freight. If it is produced in a nearby place, the price may be slightly lower.
    The price in the city changes rapidly. For real-time prices, you should consult Jia people in the city, brokers, or the Internet of business conditions to get the latest price. However, roughly speaking, the price of 2% 2C6 - diacid per kilogram is usually between eighty yuan and one hundred and fifty yuan.