2 6 Dimethyl 4 Nitropyridine
pyridine pyrrole pyrazine piperidine piperazine

2,6-Dimethyl-4-nitropyridine

    Specifications

    HS Code

    289608

    Chemical Formula C7H8N2O2
    Molar Mass 152.15 g/mol
    Appearance Solid
    Physical State At Room Temperature Solid
    Solubility In Water Low solubility in water (due to non - polar nature of dimethyl groups and hydrophobicity of the pyridine ring)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, dichloromethane

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    Frequently Asked Questions

    As a leading 2,6-Dimethyl-4-nitropyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2,6-dimethyl-4-nitropyridine?
    2% 2C6-dimethyl-4-nitroaniline, which is an organic compound. Its physical properties are as follows:
    Viewed at room temperature, it is mostly in the state of yellow to brown crystalline powder. This color and shape are caused by the interaction of specific atoms and groups in the molecular structure. It is emitted by smell, or there is a special odor, which is derived from the unique chemical composition of its molecules.
    As for the melting point, it is about 113-116 ° C. The characteristics of the melting point are closely related to the intermolecular forces. At this temperature range, the molecule is gradually energized enough to break free from the lattice binding, and the lattice structure disintegrates, and then melts from a solid state to a liquid state. < Br >
    In terms of solubility, the solubility of water is not good, because the molecular polarity is relatively small, while water is a strong polar solvent. According to the principle of "similar miscibility", the two are difficult to dissolve each other. However, in organic solvents such as ethanol and ether, the solubility is still good, and the organic solvent and the compound molecules can attract each other by van der Waals force, hydrogen bond, etc., so they are soluble.
    Density is also an important physical property, and its density is about 1.26 g/cm ³. This value reflects the mass of the substance per unit volume, which is related to the degree of close accumulation of molecules and the relative molecular mass.
    In addition, its stability needs attention. If it is heated or exposed to open flames or hot topics, there is a risk of combustion and explosion. Due to its nitro content, nitro is an oxidizing group, which is easy to decompose and release oxygen when heated, which can support combustion and cause explosion risk. When storing, it should be placed in a cool and ventilated place, away from fire and heat sources to avoid danger.
    What are the chemical properties of 2,6-dimethyl-4-nitropyridine?
    2% 2C6-dimethyl-4-nitroaniline is an organic compound. Its properties are quite unique and it has a wide range of uses in many fields.
    This compound has significant chemical properties. First, it has strong oxidizing properties. Due to the existence of nitro groups, it can exhibit oxidizing properties under specific conditions and can react with many reducing agents. Second, the presence of its substituents changes the electron cloud density of the benzene ring, which affects the activity of electrophilic substitution reactions. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring, making the electrophilic substitution reaction more likely to occur; nitro is a strong electron-absorbing group, but it will reduce the electron cloud density of the benzene ring, which has a significant impact on the localization effect of electrophilic substitution reactions. < Br >
    Physical properties can not be ignored. At room temperature, it is mostly solid, with specific melting points and boiling points. In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether, but relatively small solubility in water.
    From the perspective of stability, it can be maintained relatively stable under normal environmental conditions. In case of high temperature, open flame or strong oxidant, the stability is affected or dangerous.
    In chemical reactions, it can participate in a variety of reaction types. In addition to electrophilic substitution reactions, nitro groups can be reduced to amino groups, which can be converted into 2% 2C6-dimethyl-4-aminoaniline by appropriate reducing agent treatment. This product is widely used in dyes, pharmaceutical synthesis and other fields.
    In short, 2% 2C6-dimethyl-4-nitroaniline has rich chemical properties and is important in chemical, pharmaceutical and other industries. However, its characteristics should be paid attention to when using and storing to ensure safety.
    What are the common synthesis methods of 2,6-dimethyl-4-nitropyridine?
    The common synthesis method of 2% 2C6-dimethyl-4-nitroaniline, in the paradigm of "Tiangong Kaiwu", in classical Chinese words, is as follows:
    To obtain 2% 2C6-dimethyl-4-nitroaniline, follow the number method. First, take 2% 2C6-dimethylaniline as the base and nitrate it. Put 2% 2C6-dimethylaniline in a suitable reactor and slowly add a nitrifying reagent. This nitrifying reagent is often a mixed acid of concentrated nitric acid and concentrated sulfuric acid. For mixed acids, mix the two in a suitable ratio to adjust their nitrifying activity. When adding acid, the temperature should be carefully controlled to prevent overreaction. Usually, temperature control in the low temperature range, such as 0 to 10 degrees Celsius, can ensure the steady progress of the reaction, so that the nitro group selects the position and substitutes, mostly falling above the 4-position, to obtain the target product.
    Second, it can also be gradually derived from other substances. First, a suitable halogen is substituted with 2% 2C6-dimethylaniline. The halogen atom in the halogen is quite active, and it is easy to undergo nucleophilic substitution with the amino group of aniline. After the intermediate product is obtained, it is then nitrified. In this way, the conditions of the substitution reaction also need to be carefully observed. The choice of solvent, the amount and type of base are all related to the success or failure of the reaction and the purity of the product. When nitrifying, as in the previous method, carefully adjust the temperature and other conditions to make the nitro group just reach the 4-position, and finally obtain 2% 2C6-dimethyl-4-nitroaniline.
    In addition, there may be those who start with 2% 2C6-dimethylphenol. First, the phenolic hydroxyl group is converted into an easy-to-leave group, and then nucleophilic substitution is performed to introduce an amino-containing structure. Subsequently, the nitro group is inserted into the 4-position through nitrification. In this process, the accuracy of the group conversion and the control of the reaction conditions are all key. Each step requires fine operation to achieve the purity of the product and high yield. Although the methods of synthesis are different, they all depend on a deep understanding of the reaction mechanism and strict control of the conditions in order to achieve their goals.
    In which fields is 2,6-dimethyl-4-nitropyridine used?
    2% 2C6-dimethyl-4-nitroaniline, which is used in many fields such as medicine, dyes, and pesticides.
    In the field of medicine, it can be used as a key intermediate for drug synthesis. Due to the special chemical properties of nitro and amino groups, other functional groups can be introduced through many chemical reactions, and then complex drug molecular structures can be constructed. For example, the reduction reaction converts nitro groups into amino groups, and then reacts with other compounds containing specific functional groups to synthesize pharmaceutical ingredients with specific pharmacological activities, which are of great significance for the treatment of certain diseases.
    In the dye industry, it is an important raw material. After proper chemical modification of aniline compounds, the presence of chromophore and chromophore groups in the structure can endow the dyes with good dyeing properties and color stability. Using 2,6-dimethyl-4-nitroaniline as the starting material, through a series of diazotization and coupling reactions, a variety of dyes with bright colors and excellent fastness can be prepared, which are widely used in the dyeing of textiles, leather and other materials.
    In the field of pesticides, it can be used to synthesize some pesticides. Due to its structural characteristics, the synthesized pesticides may be biologically active to specific pests or weeds. It can interfere with the physiological and metabolic processes of pests or inhibit the growth and development of weeds, providing effective means for pest control and weed control in agricultural production, and helping to ensure the yield and quality of crops.
    What are the storage conditions for 2,6-dimethyl-4-nitropyridine?
    For 2% 2C6-dimethyl-4-nitroaniline, its existence is not yet available for investigation. This is a chemical compound, and its properties are not yet viable, so it needs to be carefully stored.
    First, avoid open flames and high temperatures. Because of its flammability, in case of open flames and high temperatures, it may burn or even explode. Therefore, the place where it exists must be a source of fire, and its environmental temperature should be controlled to prevent high temperatures.
    Second, it is suitable to be placed in a room where it is clean and well-connected. If it is low, it can reduce the reaction rate of its transformation; if it is good, it can prevent the polymerization of water and reduce the risk.
    Third, it needs to be stored in parts such as oxidation and acid. Because 2% 2C6-dimethyl-4-nitroaniline is oxidized, it is easy to oxidize and react. When it encounters acid, it may also be chemically modified, which will cause its properties to change, and even be dangerous.
    Fourth, there are suitable materials in the room to contain leaks. In order to prevent accidental leakage, it can be prevented and prevented, and it is less harmful to the environment and people. Therefore, the storage of 2% 2C6-dimethyl-4-nitroaniline must be kept in phase according to its characteristics to ensure safety.