2 6 Dim Thyl 4 2 Nitroph Nyl 1 4 Dihydropyridine 3 5 Dicarboxylate De Dim Thyle
pyridine pyrrole pyrazine piperidine piperazine

2,6-dim茅thyl-4-(2-nitroph茅nyl)-1,4-dihydropyridine-3,5-dicarboxylate de dim茅thyle

    Specifications

    HS Code

    491015

    Chemical Name 2,6 - dimethyl - 4 - (2 - nitrophenyl)-1,4 - dihydropyridine - 3,5 - dicarboxylate de dimethyle
    Molecular Formula C20H22N2O6
    Molecular Weight 386.40
    Appearance Typically a solid (color may vary)
    Melting Point Specific value would depend on purity and conditions
    Solubility Solubility characteristics in common solvents like ethanol, acetone, etc. would vary
    Density Value depends on physical state and purity
    Stability Stability can be affected by light, heat, and moisture
    Pka Values associated with acidic or basic groups in the molecule
    Logp Indicator of lipophilicity

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    Frequently Asked Questions

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    What are the chemical properties of dimethyl 2,6-dimethyl-4- (2-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate
    2% 2C6-dimethyl-4- (2-furanylphenyl) - 1% 2C4-diazonaphthalene-3% 2C5-dimethyl dicarboxylate, this is an organic compound. Its chemical properties are quite complicated, let me tell you in detail.
    From the structural point of view, the compound contains dimethyl, furanylphenyl, diazonaphthalene and dimethyl dicarboxylate. These groups interact to give it unique chemical properties.
    Stability is first mentioned. The structure of diazanaphthalene makes the molecule have certain aromatic stability, and the conjugated system can disperse the electron cloud, reduce the internal energy of the molecule, and improve the stability. The existence of dimethyl, because methyl is the power supply group, can affect the electron cloud density of surrounding atoms, and moderately change the molecular stability and reactivity.
    Re-discussion of solubility. Because of the ester group (dimethyl dicarboxylate), the compound has a certain solubility in organic solvents such as chloroform and dichloromethane. The ester group itself has a certain polarity, and it can interact with organic solvents to form van der Waals forces, which is conducive to dissolution. However, due to the relatively large molecule and the aromatic structure, its solubility in water is not good, because it is difficult to form a good interaction between water molecules and the molecule, and the non-polar part of the molecule is large, and the pol
    Talking about the reactivity, the furan ring of furanylphenyl is electron-rich and prone to electrophilic substitution reaction. Electrophilic reagents are prone to attack areas with high electron cloud density of furan ring and initiate substitution reactions. At the same time, the ester group of dimethyl dicarboxylate can undergo hydrolysis, alcoholysis and other reactions. Under acidic or basic conditions, ester groups can be hydrolyzed to carboxylic acids or carboxylic salts; under the action of alcohols in catalysts, alcoholysis can occur to form new esters.
    In summary, 2% 2C6-dimethyl-4- (2-furanylphenyl) -1% 2C4-diazonaphthalene-3% 2C5-dicarboxylic acid dimethyl ester is characterized by its unique structure, stability, solubility and reactivity, and may have important uses in organic synthesis and related fields.
    What are the synthesis methods of dimethyl 2,6-dimethyl-4- (2-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate
    The synthesis method of 2% 2C6-dimethyl-4- (2-furanylphenyl) -1% 2C4-dihydropyridine-3% 2C5-dicarboxylic acid dimethyl ester, in the era of "Tiangong Kaiqi", although there is no modern fine organic synthesis method, it can also be explored according to the idea of ancient chemical operation.
    Ancient alchemy and alchemy have accumulated a lot of experience in material transformation. To form this compound, you can first observe its structure and disassemble it into several simple fragments.
    The selection of raw materials requires substances containing methyl, furanyl, phenyl and other structures. In ancient methods, components containing corresponding groups can be extracted from natural products. Such as certain plants or minerals, or substances containing methyl structure, with appropriate treatment, can be used as the basis for the introduction of methyl.
    For furyl and phenyl structures, similar aromatic natural products can be started. Although there is no precise organic synthesis method in ancient times, natural materials can be treated by heating, distillation, extraction and other methods to obtain substances with similar structures.
    Synthetic process, analogous to the reaction conditions of ancient methods. Heating is a common means of promoting reaction. It can be used in special ceramic or metal containers to control the temperature and make the raw materials interact. For example, heating with charcoal fire, according to the size and duration of the fire, the reaction process can be regulated.
    In the reaction system, some natural acid-base substances can be used as catalysts. For example, plant ash contains potassium carbonate, which is weakly alkaline, or can promote certain reaction steps. Or use vinegar and other acidic substances to catalyze specific reactions.
    Separation and purification, there are ancient methods. Using the difference in solubility of substances, water, wine, etc. as solvents, dissolution, filtration, recrystallization and other operations are carried out to obtain relatively pure products.
    Although ancient methods are difficult to achieve the precision and efficiency of modern synthesis, according to the wisdom and practical means of the ancients, the initial path of synthesizing this compound can be explored, which will pave the foundation for the development of synthetic chemistry in later generations.
    What are the applications of dimethyl 2,6-dimethyl-4- (2-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate in the field of medicine?
    2% 2C6-dimethyl-4- (2-furanylphenyl) - 1% 2C4-dihydropyridine-3% 2C5-dimethyl dicarboxylate, which is widely used in the field of medicine.
    First, it plays an important role in the prevention and treatment of cardiovascular diseases. It is like a skilled craftsman who can precisely control the cardiovascular system, which can effectively dilate blood vessels, just like building a more spacious channel for blood vessels, so that blood can flow smoothly, thereby lowering blood pressure and relieving the pressure on the heart. In addition, it can optimize the blood supply of the myocardium, just like injecting a source of vitality into the myocardium, enhancing myocardial function, and has a good therapeutic effect on coronary heart disease, angina pectoris and other diseases.
    Second, in the field of nervous system diseases, it also has extraordinary performance. It is like a guardian of the nervous system, which can regulate the function of nerve cells and maintain the stability of nerve transmission. For neurological diseases such as migraine and Parkinson's disease, it has a certain relieving and therapeutic effect, as if it can rearrange the disordered neural order.
    Third, its efficacy in anti-atherosclerosis should not be underestimated. It is like a diligent scavenger, which can inhibit the formation and development of atherosclerotic plaques, clean up the "garbage" on the blood vessel wall, reduce blood lipids, stabilize plaques, and effectively prevent the occurrence of cardiovascular events, just like building a strong defense line for vascular health.
    Fourth, it also plays a key role in the prevention and treatment of diabetic complications. It can improve the vascular function of diabetic patients, reduce microvascular lesions, such as providing strong support for the fragile blood vessels of diabetic patients, and has positive significance for the prevention and treatment of diabetic nephropathy, retinopathy and other complications.
    What are the market prospects for dimethyl 2,6-dimethyl-4- (2-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
    2% 2C6-dimethyl-4- (2-furanylphenyl) - 1% 2C4-dihydropyridine-3% 2C5-dimethyl dicarboxylate, this compound has many advantages in terms of market prospects. In the field of pharmaceutical research and development, due to its unique structure, it can provide novel ideas for the creation of drugs for cardiovascular diseases. Cardiovascular diseases are a high-incidence disease in the world, and the demand for specific therapeutic drugs continues to rise. This compound may be optimized to become a targeted therapeutic drug, and the market demand is considerable.
    In the field of materials science, the characteristics endowed by its structure may emerge in the synthesis of new organic materials. With the development of science and technology, the demand for high-performance organic materials is increasing. For example, in the field of optoelectronic materials, the compound may be modified to show excellent optoelectronic properties and applied to new display technologies, etc., opening up a broad market space.
    At the level of pesticide research and development, the compound may have potential biological activity. After research and optimization, high-efficiency, low-toxicity, and environmentally friendly pesticides can be developed, which is in line with the current development trend of green agriculture and has broad market prospects.
    However, its market expansion also faces challenges. R & D costs are high, and a lot of money and time are required from basic research to product launch. And the market competition is fierce, and there are many mature products and R & D projects in related fields. But overall, if the challenge can be effectively overcome, with its own characteristics, 2% 2C6-dimethyl-4- (2-furanylphenyl) -1% 2C4-dihydropyridine-3% 2C5-dimethyl dicarboxylate is expected to occupy an important market position in many fields, creating considerable economic and social benefits.
    What are the precautions in the preparation of dimethyl 2,6-dimethyl-4- (2-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
    To prepare 2,6-dimethyl-4- (2-furanyl) -1,4-dihydropyridine-3,5-dicarboxylate diethyl ester, the following things should be paid attention to:
    The first is the purity of the raw material. The purity of the raw material is related to the reaction effect and the quality of the product. For example, if 2-furanaldehyde contains impurities or causes side reactions, the purity of the product will be reduced and the yield will be low. Therefore, the raw materials need to be purified finely before use, and the high purity of the raw materials should be ensured by distillation, recrystallization and other methods.
    The second is the temperature of the reaction. This reaction is sensitive to temperature. If the temperature is too high, side reactions are easy to occur, such as excessive condensation of pyridine rings, and the product is complex and difficult to separate. If the temperature is too low, the reaction rate is slow, time-consuming and the yield is not good. It is advisable to precisely control the temperature, and use temperature control devices such as oil bath and water bath to make the reaction proceed smoothly in a suitable temperature range (often specified in specific documents).
    Furthermore, the amount of catalyst is used. The catalyst can promote the reaction to accelerate, and the improper amount will affect the reaction. If the amount is small, the catalytic effect is not obvious, and the reaction is slow; if the amount is large, the side reaction may be intensified. The amount of catalyst should be accurately determined by pre-experiment according to the reaction scale and the amount of raw materials.
    The reaction time is insufficient, the raw materials are difficult to be fully converted, and the yield is low; if the time is too long, the product may be decomposed or other side reactions may occur. During the reaction process, real-time monitoring is required by means of thin-layer chromatography (TLC), etc., to achieve the expected degree of reaction, that is, to terminate the reaction in a timely manner.
    There is also a choice of solvent. A suitable solvent can help the reactants to disperse uniformly, which is beneficial to the reaction. Solvent polarity, solubility and other properties have a great impact on the reaction. Choose the wrong solvent, or cause the reactants to dissolve poorly, and the reaction is difficult to occur. According to the reaction characteristics and the properties of the reactants, choose the matching solvent.
    The final is the separation and purification of Appropriate separation and purification methods, such as column chromatography, distillation, extraction, etc. should be used to obtain high-purity products. During operation, attention should be paid to the conditions and parameters of each link to ensure the separation and purification effect.