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What are the main uses of 2,6-dihydroxy-5-fluoro-3-cyanopyridine?
The main uses of 2% 2C6-difluoro-5-bromo-3-bromo-pyridine are as follows:
In the field of medical chemistry, this compound is often used as a key intermediate. Due to its unique chemical structure, fluoro, bromo and other substituents endow it with special reactivity and physicochemical properties. Through clever organic synthesis methods, it can be used to construct complex drug molecular skeletons. For example, in the development of anticancer drugs with specific targeting properties, the compound can be used as a starting material to react with other molecules containing specific active groups. After a series of substitution, condensation and other reaction steps, the drug molecular structure with the required pharmacological activity can be accurately built, providing a strong material basis for the treatment of major diseases such as cancer.
In the field of pesticide chemistry, it also plays an important role. With its own structural characteristics, it can be transformed into highly efficient, low-toxic and environmentally friendly pesticides. For example, in the creation of new insecticides, as a core structural unit, it can regulate the interaction between compounds and specific biological targets in pests by reasonably modifying peripheral substituents, thereby enhancing the toxic effect on pests, while reducing the negative impact on non-target organisms and the environment, and helping agricultural production achieve green and sustainable development.
In terms of materials science, 2% 2C6-difluoro-5-bromo-3-bromo-pyridine also shows application potential. It can be introduced into the molecular design of organic optoelectronic materials. Due to the electronegativity difference between fluorine and bromine atoms, the electron cloud distribution and energy level structure of the material can be adjusted, thereby optimizing the photoelectric properties of the material. Like in the development of organic Light Emitting Diode (OLED) materials, the use of this compound to participate in the construction of luminescent materials is expected to achieve higher luminous efficiency and color purity, driving display technology to new heights.
What are the physical properties of 2,6-dihydroxy-5-fluoro-3-cyanopyridine
2% 2C6-diamino-5-cyano-3-cyanopyridine has the following physical properties:
This compound is usually in solid form at room temperature and pressure. Its appearance may be white to light yellow crystalline powder, the specific color will vary depending on the purity and preparation process.
In terms of solubility, its solubility in water is relatively low. This is because the compound molecule contains more polar groups, such as amino, cyano, etc. Although it has a certain polarity, the complexity of the overall structure makes it difficult to fully interact with water molecules and dissolve in large quantities. However, in some organic solvents, such as ethanol and dichloromethane, its solubility will increase. Ethanol, as a commonly used organic solvent, can interact with the compound molecules through hydrogen bonds, etc., so that some compound molecules can be dispersed in the ethanol solvent.
From the perspective of melting point, it has a certain melting point range, which is related to the interaction forces between molecules. There are van der Waals forces, hydrogen bonds and other forces between molecules. These forces cause molecules to overcome the interaction and undergo a phase transition at a certain temperature, from solid to liquid. The specific melting point value will fluctuate slightly due to different purity, but it is roughly within a specific temperature range.
The density of this compound also has its own specific value. The density reflects the mass per unit volume of a substance. It depends on the structure of the molecule and the way the molecules are packed. The type, number and spatial arrangement of atoms in its molecular structure together determine its density characteristics.
What are the synthesis methods of 2,6-dihydroxy-5-fluoro-3-cyanopyridine
To prepare 2,6-dinitro-5-bromo-3-bromomethylpyridine, there are many ways to synthesize it.
First, it can be started from a suitable pyridine derivative. First, bromine atoms are introduced at specific positions on the pyridine ring, and by means of halogenation reaction, suitable halogenating reagents, such as bromine and appropriate catalysts, are selected to precisely replace the target position hydrogen atoms under appropriate reaction conditions. Subsequently, a nitrification reaction is carried out. A mixed system of concentrated nitric acid and concentrated sulfuric acid is used to control the reaction temperature, time and other conditions. Nitro groups are introduced into the pyridine ring, and the desired molecular structure is gradually constructed through multi-step reactions.
Second, other nitrogen-containing heterocyclic compounds can also be designed as raw materials, through cyclization, substitution and other series of reactions. For example, the heterocyclic intermediate with part of the target structure is synthesized first, and then brominated and nitrified by specific reagents and reaction conditions. For example, a nitrogen-containing precursor compound is introduced into bromomethyl by reacting with halogenated hydrocarbons under basic conditions, and then brominated and nitrified to achieve the conversion to the target product.
Third, metal-catalyzed reactions can also be used. With the help of transition metal catalysts, such as palladium, copper and other catalytic coupling reactions, small molecule fragments containing bromine, nitro and other functional groups are connected to pyridine derivatives. By rationally designing the reaction substrate and catalyst system, the reaction conditions are optimized to obtain the target product with high selectivity and yield. During the reaction, attention should be paid to the influence of factors such as catalyst dosage, ligand selection, reaction solvent and temperature on the reaction.
To synthesize this compound, each method should pay attention to the precise control of the reaction conditions, such as temperature, pH, reaction time, etc., to ensure that the reaction proceeds in the expected direction and improve the purity and yield of the product. After each step of the reaction, separation and purification methods, such as column chromatography, recrystallization, etc. are often used to obtain pure intermediates and final products.
What is the price range of 2,6-dihydroxy-5-fluoro-3-cyanopyridine in the market?
Nowadays, there are diphenol-5-ene-3-hydroxypyridine, and the price range on the market will be described in the style of "Tiangong Kaiwu".
Fudiphenol-5-ene-3-hydroxypyridine is a very useful substance in the chemical industry. The price range is subject to many factors.
First, the cost of raw materials is the key. If the raw materials required to prepare this compound are difficult to obtain and expensive, the price of this product will also be high. If the raw materials need to be refined finely, or the origin is far away, and the transportation cost is expensive, the cost will rise, which will then increase the market price.
Second, the complexity of the preparation process also affects. If the preparation method is complicated, special equipment, precise operation and long time are required, during which human and material resources are consumed, the price is naturally not low. On the contrary, if the process is simple and can be mass-produced, the price may be reduced.
Third, the supply and demand relationship in the market also affects the price. If the market demand for this product is strong and the supply is limited, the so-called "rare is expensive", the price will rise; if the supply exceeds the demand, the merchant may reduce the price in order to sell its goods.
Overall, the price range of diphenol-5-ene-3-hydroxypyridine in the market can range from ten dollars per single digit to hundreds of dollars. However, this is only an approximate number. The actual price varies with the above factors, or fluctuates up and down. The industry can only know the exact price when considering the situation and observing the changes in the market.
What are the storage conditions for 2,6-dihydroxy-5-fluoro-3-cyanopyridine?
The storage conditions of 2% 2C6-difluoro-5-bromo-3-bromo-pyridine are as follows:
This compound contains special groups such as fluorine and bromine, and its properties are relatively active. It needs to be properly stored to maintain its chemical stability. It should be stored in a cool and dry place. Due to high temperature, it may promote the thermal movement of molecules to intensify, trigger chemical reactions, cause decomposition or deterioration; environmental humidity can easily make the compound absorb moisture, which may change its physical and chemical properties, and even cause reactions such as hydrolysis.
Ensure that the storage environment is well ventilated. The substance may volatilize trace amounts of harmful gases. Good ventilation can disperse in time, reduce safety risks, ensure the air quality of storage space, and avoid the accumulation of harmful gases to cause harm to personnel and the environment.
Be sure to place it in a sealed container. Sealing can effectively isolate air and moisture, prevent oxygen oxidation compounds, and moisture from participating in chemical reactions, minimize contact with the external environment, and maintain its chemical structure and purity.
Storage sites should be kept away from fire sources, heat sources, and strong oxidants. Due to its chemical structure characteristics, in case of open flames, hot topics, or contact with strong oxidants, there is a risk of combustion and explosion. Strict isolation can greatly reduce safety hazards and ensure the safety of the storage process. < Br >
For such organic compounds containing special groups, following the above storage conditions can ensure their quality and stability for subsequent scientific research, production, and other uses.