2 6 Difluoropyridine 4 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,6-difluoropyridine-4-carboxylic acid

    Specifications

    HS Code

    869508

    Name 2,6-difluoropyridine-4-carboxylic acid
    Molecular Formula C6H3F2NO2
    Molecular Weight 159.09
    Appearance Solid (likely white to off - white)
    Cas Number 112890-00-3
    Boiling Point Data may vary, around 280 - 290°C (estimated based on related compounds)
    Melting Point 185 - 187°C
    Solubility In Water Poor solubility in cold water, solubility may increase with temperature
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Acidity Weakly acidic due to the carboxylic acid group, pKa value around 3 - 4 (estimated for pyridine - carboxylic acid derivatives)

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    General Information
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    Frequently Asked Questions

    As a leading 2,6-difluoropyridine-4-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-difluoropyridine-4-carboxylic acid?
    2% 2C6-diethoxybenzene-4-carboxylic acid, this substance has a wide range of uses. In the field of medicine, it is a key intermediate for drug synthesis. Taking the creation of drugs for the treatment of cardiovascular diseases as an example, it can participate in the construction of molecular structures with specific pharmacological activities. With its unique chemical properties and reactivity, it can help form active ingredients that effectively act on the cardiovascular system, providing strong support for disease treatment.
    In the field of materials science, it can be used as an important raw material for the synthesis of materials with special functions. For example, when preparing polymer materials with specific optical and electrical properties, introducing them into the polymer structure can endow the materials with unique properties such as light absorption and conductivity, and meet the needs of materials for special properties in fields such as photoelectric display and semiconductors. In the field of organic synthesis, it plays an indispensable role. As an important reaction substrate, it participates in many organic reactions, such as esterification and acylation reactions. Through these reactions, a series of organic compounds with diverse structures and functions can be derived, providing a rich material basis for the development of organic synthetic chemistry and greatly promoting the progress and innovation of organic synthetic chemistry.
    What are the synthesis methods of 2,6-difluoropyridine-4-carboxylic acid?
    The synthesis method of 2% 2C6-divinylbenzene-4-carboxylic acid is an important topic in the field of organic synthesis. To make this compound, there are several common methods.
    First, benzene derivatives are used as starting materials. First, take benzene with appropriate substituents, such as p-carboxylbenzene, and introduce halogen atoms through halogenation reaction. The commonly used halogen is bromine or chlorine. This step requires appropriate halogenation reagents and reaction conditions. For example, liquid bromine and iron powder catalyze to obtain halogenated p-carboxylbenzene. Then, through a metal-catalyzed coupling reaction, such as Suzuki coupling or Heck coupling reaction, halogenated p-carboxyl benzene is reacted with vinyl borate or vinyl halide, and then vinyl is introduced. After multi-step reaction and purification steps, the target product 2% 2C6-divinylbenzene-4-carboxylic acid can be obtained.
    Second, a simple compound containing carboxyl and vinyl can also be used as a raw material for intramolecular cyclization. If an appropriate unsaturated carboxylic acid ester is used as the starting material, under specific catalyst and reaction conditions, the intramolecular cyclization occurs to construct a benzene ring structure, and the carboxyl group and vinyl group are retained. This process requires precise regulation of reaction temperature, catalyst dosage and reaction time to achieve ideal yield and selectivity.
    Third, carboxyl groups can also be introduced through carboxylation reaction starting from divinylbenzene. Among them, suitable carboxylation reagents, such as carbon dioxide and suitable metal catalyst system, can be used to react at a certain pressure and temperature to carboxylate divinylbenzene, thereby obtaining 2% 2C6-divinylbenzene-4-carboxylic acid. However, this process requires considerable equipment and operation, and it is necessary to exercise caution to ensure the smooth progress of the reaction and the purity of the product.
    What is the market price of 2,6-difluoropyridine-4-carboxylic acid?
    In today's world, the business situation is complicated, and it is not easy to figure out the market price of 2,6-diethylnaphthalene-4-carboxylic acid. In the market, this price often changes due to various factors, such as the state of supply and demand, the new technology, the rules of politics and laws, the bureau of commerce, etc., which can make it fluctuate up and down.
    Those who supply and demand are the foundation of the market. If there are many people who want this thing, but there are few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price will drop. In today's chemical industry, many industries may rely on this product as a material. If the industry is prosperous and the demand is strong, the price will also be high; if the industry is sluggish, the demand will drop sharply, and the price will inevitably fall.
    The new process is also the key. If the new technology is released, which increases the efficiency of production and reduces the cost, there will be more goods on the market, and the price will also tend to drop; if the research and development is blocked, the production efficiency will not increase, the cost will be high, and the price will also be difficult to drop.
    The regulations of politics and laws have a great impact. Environmental protection orders and taxation are all related to the production and trade of this product. Under strict laws, production is limited, supply or contraction, and prices may rise as a result; conversely, policies are favorable, or production is promoted, supply is increased, and prices are leveled.
    The situation of commerce and trade cannot be ignored. International trade, tariffs and exchange rates can change their prices. Trade is peaceful, logistics is smooth, and prices are stable; if disputes arise and trade is blocked, prices will change.
    In general, if you want to know the current market price of 2,6-diethylnaphthalene-4-carboxylic acid, you need to look at these numbers and constantly observe changes in market conditions before you can get a more accurate number. The market is impermanent, and the price is not fixed. Keep an eye out for the true picture of the market situation.
    What are the physical and chemical properties of 2,6-difluoropyridine-4-carboxylic acid?
    2% 2C6-divinylbenzene-4-sulfonic acid is an organic compound with unique physicochemical properties. It is a solid at room temperature and has a certain melting point and boiling point. The melting point causes the substance to change from solid to liquid at a specific temperature, which has a significant impact on its morphology under different conditions. In the heating or cooling process, the melting point determines the node of material state change, which is conducive to controlling the reaction process. The boiling point determines its temperature from liquid to gaseous. In chemical operations such as separation and purification, the difference in boiling point can be used to separate the substance from other components.
    This compound is acidic because it contains a sulfonic acid group. The acidic nature enables it to neutralize and react with bases to generate corresponding salts and water. In organic synthesis, this property can be used to introduce specific functional groups, change molecular structure and properties, and synthesize new organic materials. And its acidity is also used in the field of catalysis, and can be used as a catalyst for some reactions to accelerate the reaction process.
    2% 2C6-divinylbenzene-4-sulfonic acid solubility is also an important property. It has a certain solubility in some organic solvents, which facilitates its reaction in solution. In the fields of coatings, adhesives, etc., it needs to be dissolved in a suitable solvent to uniformly disperse in the system and play a corresponding role. At the same time, solubility affects its transport and diffusion in different media, which affects its effect in practical applications. In addition, the vinyl in its molecule gives it a certain reactivity, which can undergo reactions such as addition and polymerization, and is used to prepare high-molecular polymers to expand its application range.
    In which fields are 2,6-difluoropyridine-4-carboxylic acids used?
    2% 2C6-diethoxybenzene-4-carboxylic acid has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help synthesize a variety of drugs. For example, the synthesis of compounds with specific physiological activities, or the preparation of pharmaceutical components for the treatment of certain diseases, provides an important material basis for the research and development of medicine.
    In the field of materials science, this compound may participate in the creation of new materials. Its unique chemical structure may endow materials with special properties, such as improving material stability, solubility, and even affecting the optical and electrical properties of materials, which contribute to material innovation.
    In the field of organic synthesis, it is an important synthetic building block. With its functional group characteristics, it can build complex organic molecular structures through various chemical reactions, greatly expanding the possibility of organic synthesis and promoting the development of organic chemistry.
    In addition, it may also have applications in the fragrance industry. Due to its chemical structure, it may be able to derive substances with special aromas, adding unique ingredients to the preparation of fragrances and enriching the variety of fragrances. In short, 2% 2C6-diethoxybenzene-4-carboxylic acid plays a role that cannot be ignored in many fields, providing assistance for the development of various fields.