2 6 Difluoro 3 Pyridine Boronic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,6-Difluoro-3-pyridine boronic acid

    Specifications

    HS Code

    739472

    Chemical Formula C5H4BF2NO2
    Molecular Weight 158.90
    Appearance White to off - white solid
    Melting Point 120 - 125°C
    Boiling Point N/A (decomposes before boiling)
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethanol
    Pka Value N/A
    Density N/A
    Stability Stable under normal conditions, but moisture - sensitive

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    General Information
    Where to Buy 2,6-Difluoro-3-pyridine boronic acid in China?
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    Frequently Asked Questions

    As a leading 2,6-Difluoro-3-pyridine boronic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-difluoro-3-pyridyboronic acid?
    2% 2C6-diene-3-pentanoic acid, which is a crucial raw material in the field of organic synthesis. Its main use is to act as a key intermediate in organic synthesis reactions.
    The process of organic synthesis, the construction of many complex organic compounds with special structures and functions, often depends on this intermediate. Because of its unique molecular structure, it contains diene and pentanoic acid. This special structure gives it unique chemical activity and reactivity. It can be cleverly connected with other compounds through various chemical reactions, such as addition, cyclization, etc., to gradually build the complex structure of the target product.
    Furthermore, it also has important uses in the field of medicinal chemistry. The synthesis of many drug molecules may require materials containing specific structural fragments as starting materials or intermediates. The structure of 2% 2C6-diene-3-valerynic acid may be appropriately modified and converted into the molecular structure of the drug, thereby endowing the drug with specific pharmacological activity and providing a key material basis for the development and creation of new drugs.
    In addition, in the field of materials science, it may be able to participate in the synthesis of functional materials. After polymerization or reaction with other monomers or compounds, its special structure and properties can be introduced into the material, thereby imparting special optical, electrical or mechanical properties to the material, expanding the application range and performance advantages of the material.
    In summary, 2% 2C6-diene-3-valerynic acid, with its unique structure and rich reactivity, plays an indispensable role in many fields such as organic synthesis, medicinal chemistry, and materials science. It is of great significance to promote scientific research and technological development in related fields.
    What are the physical properties of 2,6-difluoro-3-pyridyl boronic acid?
    2% 2C6-diethyl-3-nitrobenzoic acid is an organic compound with the following physical properties:
    In appearance, it is often in the state of a crystalline solid. This characteristic is due to the existence of various forces between molecules, such as van der Waals force and hydrogen bonding, which promote the regular arrangement of molecules and then crystallize. Due to the molecular structure containing different groups such as benzene ring, carboxyl group and nitro group, each group absorbs and scatters light differently, resulting in a specific crystalline appearance.
    In terms of melting point, the melting point of such compounds is relatively high. Benzene ring is a rigid structure with a conjugated system, which enhances the stability of the molecule; carboxyl group can form intermolecular hydrogen bonds, and nitro group has strong electron absorption, which affects the intermolecular force. The combination of many factors increases the energy required to destroy the lattice, and the melting point increases.
    In terms of solubility, it is slightly soluble in water. Water is a polar solvent, and although the compound contains carboxyl groups, it can form hydrogen bonds with water, but the benzene ring and ethyl group are non-polar groups, accounting for a large proportion, which dominates the solubility of the molecule, making the overall interaction with water weak, so it is slightly soluble. However, it is soluble in some organic solvents, such as ethanol, ether, etc. Organic solvents such as ethanol can form similar forces between molecules of the compound, such as van der Waals force, and some can also form hydrogen bonds with carboxyl groups to help it dissolve.
    In terms of density, the relative density is greater than 1. Due to the variety of atoms in the molecule and the large atomic weight, such as the benzene ring containing multiple carbon atoms, the nitrogen and oxygen atoms in the nitro group, and the atoms carried by the ethyl group itself, the mass per unit volume is relatively high, resulting in a density greater than that of water.
    On the odor, there may be a weak special smell. This is due to its unique molecular structure, and the combination of specific groups produces volatile substances that stimulate olfactory receptors, but usually the smell is not strong.
    What are the synthesis methods of 2,6-difluoro-3-pyridyl boronic acid?
    The synthesis of 2% 2C6-diethyl-3-pentyne acid is a key issue in the field of organic synthesis. The synthesis of this compound requires delicate design and skilled techniques. The following are common synthesis methods.
    First, a suitable halogenated hydrocarbon can undergo a nucleophilic substitution reaction with sodium alkyne. Select a suitable halogenated alkane and place it in a suitable solvent with a sodium alkyne reagent. For example, by reacting halogenated ethane with the prepared sodium pentyne, and carefully controlling the reaction conditions, such as temperature, time and proportion of reactants, the target product precursor can be obtained. After acidification, the resulting alkynyl alkylate is converted into 2% 2C6-diethyl-3-valerynic acid. The advantage of this method is that the reaction steps are relatively clear, and the raw materials are easy to obtain. However, the reaction conditions need to be precisely controlled to ensure the yield and purity.
    Second, the addition reaction of carbonyl compound and alkynide is used. Select the appropriate aldehyde or ketone and add it to the alkynyl lithium or alkynyl magnesium reagent. For example, the valeraldehyde and the diethynyl lithium reagent react at low temperature and under the protection of inert gas to form the alkynyl alcohol intermediate. After the oxidation step, the alkynyl alcohol is oxidized to the corresponding carboxylic acid to obtain 2% 2C6-diethyl-3-valerynic acid. This path can flexibly introduce different substituents to improve the structural diversity of the product. However, the oxidation step needs to choose the appropriate oxidant and conditions to avoid excessive oxidation or side reactions.
    Third, the coupling reaction of alkynes is used. With the help of transition metal catalysis, alkynes are coupled to halogenated hydrocarbons or alkenyl halides. For example, palladium catalyzed system is used to react pentyne with diethylhalogenated hydrocarbons in the presence of ligands. After optimizing the reaction parameters, the carbon-carbon bond of the target molecule can be constructed, and then 2% 2C6-diethyl-3-valerynic acid can be obtained through the carboxylation step. This method relies on a highly efficient catalytic system, which can achieve complex molecular construction, requires high reaction equipment and operation, and may affect large-scale production of catalysts.
    What are the precautions for storing and transporting 2,6-difluoro-3-pyridyboronic acid?
    2% 2C6-diene-3-alkynylbenzoic acid should pay attention to the following things during storage and transportation:
    First, because of its special chemical structure, containing conjugated dienes and alkynyl groups, it is chemically active and easy to cause chemical reactions. When storing, it must be placed in a cool, dry and well-ventilated place, away from fire, heat and oxidants. If coexisted with strong oxidants, it is very easy to trigger violent oxidation reactions, even the risk of combustion or explosion.
    Second, the substance is sensitive to light and air. Light or long-term exposure to air may cause structural changes and performance degradation. Therefore, it is advisable to use a light-shielding container for storage, and it is tightly sealed to minimize contact with air. Light-shielding and sealing measures should also be taken during transportation to prevent it from being affected by light and air.
    Third, 2% 2C6-diene-3-alkynylbenzoic acid may have certain toxicity and irritation. When operating, be sure to take appropriate protective measures, such as protective clothing, gloves and goggles, to avoid skin contact and inhalation. In case of accidental contact, rinse with plenty of water immediately and seek medical treatment according to specific circumstances.
    Fourth, the transportation process should follow relevant regulations and standards. Compliance transportation tools and packaging materials should be used to ensure the stability and safety of substances during transportation. Packaging must be sturdy to prevent leakage, collision and damage. At the same time, shipping documents should specify the nature of the material, hazards and emergency treatment methods in order to deal with emergencies.
    What is the market price of 2,6-difluoro-3-pyridyboronic acid?
    Today there are twenty-six generations who are suffering from the disease of two or three. The product involved is called hexadecarboxylic-diene-3-pentenoic acid. As for the price of this product in the market, it is difficult to determine it. The price of it is determined by various factors.
    The first to bear the brunt is the trend of supply and demand. If there are many people in the world who want this product, but there are few people who produce it, the price will be high; on the contrary, if the supply exceeds the demand, the price will naturally decline. For example, in the valley of abundant years, the supply is sufficient and the price is flat; in the age of hunger, the grain is more and the price is rising.
    The second is related to the difficulty of production. If the system of this thing requires rare materials and exquisite skills, over time, it will necessarily be high, and the price will also increase. There is no reason why the price is not high.
    Furthermore, the changes of the city and the regulations of the government also have an impact. The changing situation of the city, such as the replacement of other things, the rise and fall of the tide, can move the price. The regulations of the government, or the promotion of production, or the restriction of trade, can also make the price change.
    In addition, the quality is different from the price. Those who are pure, use them well, and the price is often higher than those who are poor. Just like craft wine, with excellent taste and quality, the price is higher than that of ordinary wine. < Br >
    However, I have searched all over the cities, but I have not been able to obtain a definite number. Or because this item is not a regular product of the market, and the circulation is not wide, it is difficult to determine the price. To know the details, when you visit the elders in the various industries, and inquire about the households of production and sales, and observe the changes in the city and the differences in the analysis of feelings, you can get a more accurate price.