2 6 Dichloropyridine 4 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

2,6-dichloropyridine-4-carbonitrile

    Specifications

    HS Code

    498372

    Chemical Formula C6H2Cl2N2
    Molecular Weight 173.00
    Appearance Solid (Typical)
    Color White to off - white
    Odor Typically has a characteristic odor
    Melting Point 108 - 112 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2,6-dichloropyridine-4-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-dichloropyridine-4-formonitrile?
    2% 2C6-dinitrotoluene-4-aminosulfonic acid, its main use is particularly important. This substance is used in the manufacture of fireworks and has many applications. Due to its chemical properties, the cover can make fireworks bloom with more brilliant colors and increase its ornamental effect.
    In the military field, it also has its own shadow. It can be used as an ingredient of explosives, with the powerful energy released by its own reaction, it produces huge destructive power and plays a key role in war.
    In addition, it is also indispensable in the dye industry. It can be used as a raw material through a series of processes to produce dyes with bright colors and good fastness, which can be used in many aspects such as fabric dyeing to meet the diverse needs of the public for color.
    In addition, in some special chemical synthesis reactions, 2% 2C6-dinitrotoluene-4-aminosulfonic acid can be used as an intermediate. Through ingenious chemical reaction design, the reaction is guided to the desired product direction, which helps to synthesize various compounds with special properties and contributes to the expansion of the chemical industry.
    What are the synthesis methods of 2,6-dichloropyridine-4-formonitrile?
    2% 2C6-dihydroxypyridine-4-carboxylic acid is a key compound in the field of organic synthesis, and has a wide range of uses in the fields of medicine, pesticides and materials. Its synthesis methods are diverse and have their own advantages. The following are detailed:
    1. ** Synthesis method using pyridine as raw material **:
    -pyridine undergoes oxidation reaction under specific conditions to obtain 2,6-dihydroxypyridine. Next, 2,6-dihydroxypyridine and suitable carboxyl-containing reagents, such as halocarboxylic acids or their derivatives, undergo nucleophilic substitution reaction under alkali catalysis, resulting in 2% 2C6-dihydroxypyridine-4-carboxylic acid. The raw materials of this route are easy to find, and the operation is relatively conventional. However, the reaction steps are slightly more, and the overall yield may be limited.
    - Specifically, pyridine is oxidized with a strong oxidant, such as potassium permanganate, at an appropriate temperature and in a solvent, and the reaction conditions are precisely controlled to promote the hydroxylation of the pyridine ring at a specific position to obtain 2,6-dihydroxypyridine. Subsequently, it is heated with halogenated ethyl acetate in a suitable organic solvent in the presence of a base such as potassium carbonate, and nucleophilic substitution occurs. After hydrolysis, acidification and other steps, the final target product is obtained.
    2. ** Synthesis strategy via heterocyclic ring construction **:
    - Select suitable small molecule compounds containing nitrogen and oxygen atoms, build a pyridine ring through cyclization reaction, and introduce hydroxyl and carboxyl groups at the same time. For example, using amino acid derivatives and dicarbonyl compounds with specific structures as starting materials, under the action of acidic or basic catalysts, through a series of reactions such as condensation and cyclization, 2% 2C6-dihydroxypyridine-4-carboxylic acid can be synthesized in one or more steps. This method is relatively simple in steps and has high atomic economy. However, the preparation of raw materials may be difficult and the reaction conditions are strict. < Br > - For example, an amino acid ester and a diketone compound are heated and reacted in a solvent such as ethanol under the catalysis of ammonium acetate and an appropriate amount of acid. The key intermediate is first formed, and then the target product is obtained by subsequent treatment such as oxidation and hydrolysis.
    3. ** Biosynthetic method **:
    - Synthesis of 2% 2C6-dihydroxypyridine-4-formic acid with the help of microorganisms or enzymes. Specific enzymes in some microorganisms can catalyze the conversion of specific substrates to generate this compound. This method is green and environmentally friendly, the reaction conditions are mild, and the selectivity is very high. However, the biological system is complex, and the process of cultivating microorganisms or obtaining highly active enzymes is cumbersome, and the yield improvement is also challenging. < Br > - Such as screening specific bacterial strains, culturing in an optimized medium, using their in vivo enzymes to catalyze the transformation of specific precursor substances, and then isolating and purifying the products.
    What is the market prospect of 2,6-dichloropyridine-4-formonitrile?
    2% 2C6-diethoxyacetophenone-4-methanesulfonic acid, this product has a considerable market prospect in the current market.
    In today's chemical industry, the demand for fine chemicals is increasing. Due to its unique molecular structure, this compound can be used as a key intermediate in the field of pharmaceutical synthesis. Today, the pharmaceutical industry is booming, and new drug research and development are emerging one after another. The demand for such intermediates that can precisely build the molecular structure of drugs is also rising. For example, in the synthesis of many targeted anti-cancer drugs, 2% 2C6-diethoxyacetophenone-4-methanesulfonic acid can effectively participate in the reaction and help build complex drug active structures by virtue of its specific functional groups. Therefore, it plays a pivotal role in the anti-cancer drug research and development industry chain.
    In the field of materials science, with the increase in demand for high-end materials, this compound can be chemically modified and integrated into new material systems. For example, when synthesizing some high-performance polymer materials, adding an appropriate amount of this substance can optimize the thermal stability and mechanical properties of the material, meet the strict requirements of high-end fields such as aerospace and electronic devices, and expand its application space in the materials market.
    Furthermore, with the concept of green chemistry deeply rooted in the hearts of the people, chemical production has become increasingly concerned about the green and environmentally friendly properties of raw materials and intermediates. If 2% 2C6-diethoxyacetophenone-4-methanesulfonic acid can be further optimized in the synthesis process to achieve green and efficient preparation, it will be able to meet the general trend of market development and occupy a favorable position in the future market competition, with a bright future.
    What are the physical and chemical properties of 2,6-dichloropyridine-4-formonitrile?
    2% 2C6-dinitrotoluene-4-formic acid is an organic compound. Its physicochemical properties are as follows:
    In terms of concept, this compound is a light yellow crystalline substance, which is stable at room temperature and pressure. Regarding the melting point, it is between 180-182 ° C. At this temperature, it melts from a solid state to a liquid state. Its boiling point is higher, and it may decompose before reaching the boiling point under normal pressure, so accurate boiling point data are rare.
    In terms of solubility, it is slightly soluble in water, because water is a polar solvent, and the polar compound is weak. According to the principle of similar miscibility, it is difficult to dissolve in water. However, it can be soluble in organic solvents such as ethanol, ether, acetone, etc. Such organic solvents have moderate polarity and are similar to the structure of the compound, so they can be mutually soluble.
    Stability, stable at room temperature and pressure. However, it should be noted that it contains nitro groups, which are strong electron-absorbing groups, causing the compound to have certain oxidation and potential explosiveness. When heated, rubbed or exposed to an open flame, it may react violently and even explode.
    Chemical activity, because it contains carboxyl groups and has carboxylic acid commonality, it can neutralize with bases to form corresponding carboxylic salts and water; it can also react with alcohols under the catalysis of concentrated sulfuric acid to form esters and water. At the same time, it contains nitro groups, which can be reduced to amino groups under specific conditions, such as under the action of metals and acids.
    What are the precautions for storing and transporting 2,6-dichloropyridine-4-formonitrile?
    2% 2C6-dinitrotoluene-4-aminosulfonic acid is a highly toxic drug. When storing and transporting, you should pay great attention to the following things:
    First, the storage place must be dry and well ventilated. This drug is highly susceptible to moisture and deterioration, and humid gas can cause changes in its properties, affect its quality, or even be dangerous. And good ventilation can avoid the accumulation of harmful gases and ensure environmental safety.
    Second, temperature and humidity must be strictly controlled. If the temperature is too high, or the reaction of the drug is intensified, it will cause danger; if the humidity is too large, it will not be conducive to its existence. Therefore, it is advisable to set up a temperature and humidity monitoring device, which should be controlled within an appropriate range according to the characteristics of the drug.
    Third, the storage place should be far from the source of fire and heat. This medicine is very easy to explode when it encounters open flames and hot topics, so fireworks are strictly prohibited around, and electrical equipment must also meet explosion-proof standards.
    Fourth, during transportation, the packaging must be firm and reliable. To prevent bumps and collisions from causing package damage and medicine leakage. And transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment.
    Fifth, when handling, the operator should handle it with care. It must not be loaded and unloaded brutally to avoid accidents due to impact and friction.
    Sixth, storage and transportation need to be managed by special personnel. Managers should be familiar with the characteristics, safety knowledge and emergency handling methods of drugs, and strictly abide by relevant rules and regulations, and do a good job in warehousing and outbound registration.
    In short, the storage and transportation of 2% 2C6-dinitrotoluene-4-aminosulfonic acid is related to the overall safety situation, and all details should not be underestimated. It is necessary to be cautious to avoid disasters.