2 6 Dichloropyridine 4 Boronic Acid Pinacol Ester
pyridine pyrrole pyrazine piperidine piperazine

2,6-Dichloropyridine-4-boronic acid, pinacol ester

    Specifications

    HS Code

    961229

    Chemical Formula C11H14BCl2NO2
    Molecular Weight 274.95
    Appearance white to off - white solid
    Purity usually high - purity, e.g., >95%
    Melting Point 118 - 122 °C
    Solubility soluble in some organic solvents like dichloromethane, less soluble in water
    Stability stable under normal conditions, but moisture - sensitive
    Usage used in organic synthesis for cross - coupling reactions

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    General Information
    Where to Buy 2,6-Dichloropyridine-4-boronic acid, pinacol ester in China?
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    Frequently Asked Questions

    As a leading 2,6-Dichloropyridine-4-boronic acid, pinacol ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2,6-dichloropyridine-4-boronic acid pinacol ester?
    The main uses of 2% 2C6 -dinitrotoluene-4 -sulfonate ethyl ester are as follows:
    This compound is often an important intermediate in the field of chemical synthesis. In the preparation of dyes, it can be converted into a variety of bright colors and outstanding properties through a series of delicate chemical reactions. Due to the specific functional groups in its structure, the cover can cleverly interact with other reagents to construct dye molecules with a special color system, so that fabrics and other materials have beautiful colors and good color fastness.
    It also has extraordinary functions in the synthesis of medicine. With its unique chemical properties, it can participate in the construction of key structural fragments of drugs. Some of its functional groups can be introduced into drug molecules to change the physicochemical properties such as drug polarity and solubility, in order to improve drug bioavailability, enhance pharmacological activity or improve pharmacokinetic properties, and help the research and development of new drugs.
    In the field of materials science, it has also made a name for itself. It can be used to prepare special polymer materials, which participate in polymer polymerization reactions and can endow materials with special properties. For example, to make materials have better heat resistance, chemical corrosion resistance, or improve the electrical properties of materials, so as to expand the scope of material applications and gain important applications in high-end fields such as aerospace, electronics and electrical appliances.
    Furthermore, in the process of scientific research and exploration, as a chemical reagent with distinct characteristics, it is favored by researchers in organic synthetic chemistry, medicinal chemistry and other disciplines. To help them delve deeper into the mechanism of organic reactions, develop novel synthesis methods, and promote the continuous progress and innovation of chemical theory and technology.
    What are the synthesis methods of 2,6-dichloropyridine-4-boronic acid pinacol ester?
    There are various ways to synthesize 2% 2C6-dinitrotoluene-4-sulfonate methyl ester.
    First, it can be started from toluene. First, the toluene is nitrified. Under appropriate conditions, the mixture of 2,4-dinitrotoluene and 2,6-dinitrotoluene can be obtained by mixed acid treatment of nitric acid and sulfuric acid. Then the physical differences between the two, such as melting point and boiling point, are separated by fractionation and crystallization. 2,6-dinitrotoluene. Then, 2,6-dinitrotoluene is reacted with a sulfonating agent, such as fuming sulfuric acid, at a suitable temperature and time, and a sulfonic acid group is introduced at its 4-position to obtain 2,6-dinitro-4-toluenesulfonic acid. Finally, methanol is esterified with the sulfonic acid under the action of a catalyst such as sulfuric acid to obtain 2,6-dinitrotoluene-4-sulfonic acid methyl ester.
    Second, 2-nitrotoluene can also be used as the starting material. First, 2-nitrotoluene is nitrified under specific conditions, and another nitro group is introduced to obtain 2,6-dinitrotoluene. The following steps are similar to those of the self-toluene initiator, first sulfonation and then esterification to obtain the target product.
    Third, p-toluenesulfonic acid is used as the starting material. First, p-toluenesulfonic acid is nitrified, and the nitro group is introduced on the benzene ring. After appropriate reduction, the nitro group at the ortho-position of the sulfonic acid is converted into other exiting groups, and then the nitro group is introduced. After a series of reactions, 2,6-dinitro-4-toluenesulfonic acid is obtained, and finally esterified to obtain 2,6-dinitrotoluene-4-sulfonic acid methyl ester.
    All synthetic methods have their own advantages and disadvantages. It is necessary to consider the availability of raw materials, the level of cost, the difficulty of reaction conditions, the amount of yield and other factors according to actual needs, and choose the appropriate method.
    What are the physicochemical properties of 2,6-dichloropyridine-4-boronic acid pinacol ester?
    2% 2C6-dinitrotoluene-4-sulfonate pyridine buzzing salt is a unique chemical substance. Its physical and chemical properties are worth exploring.
    In terms of physical properties, this substance often takes a specific form. It is either crystalline, fine in texture, with a unique color in appearance, or light yellow, or slightly brown, all of which are different due to the preparation process and purity. Its crystal shape is regular, and subtle reflections can be seen under light, highlighting the order of its internal structure. Its melting point and boiling point are also important characteristics. The melting point is in a certain temperature range. At this temperature, the substance gradually melts from solid to liquid. This temperature is its inherent property and can be a key indicator for identification and purification. The boiling point is related to the transition between the gas phase and the liquid phase. Under specific pressure conditions, when the boiling point is reached, the substance will melt into a gaseous state and dissipate.
    As for the chemical properties, this substance has certain reactivity. In its molecular structure, the nitro group and the pyridinium sulfonate group give it its unique chemical behavior. Nitro has strong oxidation and can participate in many redox reactions under specific conditions. The pyridinium sulfonate part affects its ionization behavior in solution, and can undergo ion exchange and complexation reactions with other ions or molecules. Its stability is also an important consideration. Under different acid-base environments, temperatures and light conditions, its chemical structure may change differently. In an acidic environment, or its reactivity is changed due to protonation; under alkaline conditions, reactions such as hydrolysis may also occur, resulting in the destruction and transformation of its structure.
    The physical and chemical properties of this substance make it useful in many fields. However, due to its characteristics, during storage, transportation and use, it is necessary to strictly abide by relevant specifications according to its properties to ensure safety and efficacy.
    What are the precautions for 2,6-dichloropyridine-4-boronic acid pinacol ester during storage and transportation?
    2% 2C6-dinitrotoluene-4-cyanosulfonate should pay attention to the following things during storage and transportation:
    First, the storage place must be cool and dry. This material is flammable and explosive, and it is easy to cause danger in high temperature or humid places. Therefore, the temperature of the warehouse should be strictly controlled and well ventilated to prevent the accumulation of heat and moisture.
    Second, it needs to be stored separately from oxidants, acids, bases, etc. Because of its active chemical properties, contact with the above substances can easily trigger chemical reactions, and even cause combustion and explosion.
    Third, the storage place should be set up with prominent warning signs. So that relevant personnel can know at a glance that the substance is dangerous, so as to standardize the operation and avoid accidents.
    Fourth, when transporting, it is necessary to choose suitable means of transportation. Ensure that the transportation equipment is well sealed, can prevent leakage, and has corresponding safety facilities.
    Fifth, the transportation personnel must undergo professional training. Familiar with the characteristics of the substance, hazards and emergency disposal methods, in case of emergencies during transportation, they can respond quickly.
    Sixth, strictly follow the transportation regulations. According to the specified route and time of transportation, it cannot be changed at will, and the transportation documents are complete and the records are detailed.
    In short, the storage and transportation process of 2% 2C6-dinitrotoluene-4-cyanogen sulfonate must be treated with caution and operated strictly according to the specifications to ensure the safety of personnel and the environment.
    What is the market price of 2,6-dichloropyridine-4-boronic acid pinacol ester?
    Today there is dichlorohexafluoroisopropyl butyrate, what is the price in the market? This is a rare thing, and its price is not light.
    Phlorohexafluoroisopropyl butyrate is quite important in the chemical industry. However, it is also difficult to make, and it requires exquisite methods and strict procedures, and the materials used are also unusually easy to obtain.
    To make this thing, it is necessary to precisely control the temperature and humidity, strictly select the raw materials, and it is difficult to make a good product if there is a slight difference. And the equipment required must also be excellent. Therefore, its cost is quite high.
    In the market, such chemical specialties are often priced according to the quality and quantity. The price may be high if the top grade is sufficient; the second grade may be slightly reduced. And the trend of supply and demand also affects its price. If there are many people who want it, but there are few producers, the price will increase; otherwise, it may decrease slightly.
    In general, it is a genus of fine chemicals. The price per gram in the city can be as low as tens of gold, and as many as hundreds of gold is unknown. Because of its difficulty in preparation and specific use, the price is high, and unusual things can be compared. Merchants who seek to buy in the market must carefully observe its quality and weigh its price.