2 6 Dichloropyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

2,6-Dichloropyridine-3-carboxylic acid

    Specifications

    HS Code

    422605

    Chemical Formula C6H3Cl2NO2
    Molar Mass 192.00 g/mol
    Appearance White to off - white solid
    Melting Point 172 - 176 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, DMSO
    Pka Around 2.7 (approximate value for the carboxylic acid group)
    Odor Odorless (usually)

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    General Information
    Where to Buy 2,6-Dichloropyridine-3-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 2,6-Dichloropyridine-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-dichloropyridine-3-carboxylic acid?
    2% 2C6-dinitrotoluene-3-carboxylic acid, this is an organic compound, its main uses are as follows:
    First, it is of great significance in the field of pharmaceutical synthesis. It can be used as a key intermediate to help synthesize specific drugs. For example, when developing therapeutic drugs for specific diseases, its structural properties can participate in complex reaction processes, through a series of chemical reactions, converted into active ingredients with therapeutic effects, and then contribute to the development of medicine.
    Second, it plays an important role in the preparation of dyes. Because of its specific chemical structure and chromophore, it can give dyes a unique color and good dyeing properties. Through chemical modification and reaction, dyes with diverse colors and good stability can be prepared to meet the needs of textile, printing and dyeing industries for dyes of different colors and properties.
    Third, it is an extremely important raw material for the study of organic synthetic chemistry. Researchers use it to carry out research on various organic synthesis reactions, explore new reaction paths and methods, expand the synthesis of organic compounds, promote the progress and development of organic chemistry, and provide theoretical basis and practical experience for the synthesis of new functional materials and fine chemicals.
    What are the synthesis methods of 2,6-dichloropyridine-3-carboxylic acid?
    2% 2C6-dihydroxypyridine-3-carboxylic acid, the synthesis method of this compound is quite complicated, let me explain it in detail.
    One method can be started from pyridine compounds. Using suitable pyridine derivatives as raw materials, hydroxyl groups are introduced at specific positions first. For example, by means of the reaction of halogenated pyridine with nucleophiles to introduce hydroxyl groups. A strong base environment can be selected to replace the halogen atom with a hydroxyl group. This process requires fine regulation of the reaction temperature and time to prevent overreaction. After the successful introduction of one hydroxyl group, a second hydroxyl group is introduced at another specific position according to a similar reaction mechanism. This step also requires strict control of the reaction conditions to ensure that the position of the hydroxyl group introduction is accurate. < Br >
    Then, carboxyl groups are constructed at specific positions in the pyridine ring. Pyridine derivatives containing hydroxyl groups can be oxidized. A suitable oxidizing agent, such as a mild oxidizing agent, is selected in a suitable reaction solvent to oxidize the specific side chains on the pyridine ring into carboxyl groups. In this process, care should be taken to avoid excessive oxidation of the hydroxyl groups due to the influence of oxidants.
    Another method can be used to start from simple nitrogen-containing heterocyclic compounds and gradually carry out cyclization and functionalization reactions. The pyridine ring skeleton is first constructed through a multi-step reaction, and the activity check points that can introduce hydroxyl and carboxyl groups are cleverly reserved during the construction process. After the pyridine ring is formed, the corresponding check points are hydroxylated and carboxylated respectively. The hydroxylation can be achieved by metal-catalyzed nucleophilic substitution reaction, and the carboxylation can be achieved by the reaction of organometallic reagents and carbon dioxide.
    The key to synthesizing 2% 2C6-dihydroxypyridine-3-carboxylic acid is to precisely control the check point selectivity of each step of the reaction, the mildness and controllability of the reaction conditions, so that the target product can be obtained efficiently and with high purity.
    What is the market price of 2,6-dichloropyridine-3-carboxylic acid?
    Wen Ru asked about the market price of 2,6-dinitrotoluene-3-carboxylic acid. This is a chemical product, and its price often changes with time, place, and supply and demand.
    At present, in the market, its price may fluctuate between [X] yuan and [X] yuan per ton. If the supply is wide and the demand is scarce, the price will decrease; if the supply is small and the demand is large, if the chemical production and demand are in peak season, or the raw material procurement is difficult, resulting in a reduction in production, the price will rise.
    And the origin is different, the price is also different. If the product is close to the source of raw materials, or if the process is refined but the cost is low, its sale may be inexpensive; if the source of raw materials is far away, plus the cost of transportation, the cost of production will increase, and the price may be high.
    In addition, the quality is also related to the price. Those who are of high quality need more in the field of special use, and the price is often high; those who are of inferior quality have limited use and poor price.
    To know the exact price, consult the chemical raw material supplier, or visit the platform and market of the industry, to obtain the real-time price for the basis of business strategy.
    What are the physical and chemical properties of 2,6-dichloropyridine-3-carboxylic acid?
    2% 2C6-dioxypiperazine-3-carboxylic acid is an organic compound. Its physical and chemical properties are unique.
    Looking at its appearance, it often takes the form of white to off-white crystalline powder, which is easy to identify and operate. When it comes to solubility, its solubility in water is limited, but it shows good solubility in organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc. This property is extremely critical in organic synthesis operations, because good solubility helps the reaction to proceed fully.
    As far as the melting point is concerned, it is about 200-210 ° C, and the melting point is relatively high, reflecting the strong intermolecular force and the stability of its structure. In terms of stability, under conventional conditions, if properly stored, it can be maintained. However, care should be taken to avoid contact with strong oxidizing agents and strong acids and bases, because it may cause chemical reactions and destroy the molecular structure.
    2% 2C6-dioxypiperazine-3-carboxylic acid The acidity and alkalinity of its molecular structure contains carboxyl groups, so it presents a certain acidity, which can neutralize and react with bases to generate corresponding salts. This property is widely used in drug synthesis and separation and purification. At the same time, its special structure endows it with certain biological activity. In the field of medicine, it can be used as a key intermediate for the synthesis of a variety of compounds with potential pharmacological activities, providing the possibility for the development of new drugs.
    What are the precautions for storing and transporting 2,6-dichloropyridine-3-carboxylic acid?
    2% 2C6-dinitrotoluene-3-sulfonic acid is one of the chemical substances. During storage and transportation, many matters should be paid attention to.
    Bear the brunt, when storing, must choose a cool and ventilated warehouse. This substance is flammable, explosive, high temperature or dangerous, so the temperature in the warehouse should not be too high, and must be kept away from fire and heat sources. The lighting, ventilation and other facilities in the warehouse should be explosion-proof, and the switch should be set outside the warehouse to prevent accidents caused by electric sparks.
    Furthermore, it should be stored separately from oxidizing agents, reducing agents, acids, bases, etc., and must not be mixed. Due to its active chemical properties, contact with other substances, or severe chemical reactions, causing explosions, fires and other disasters.
    As for transportation, extreme caution is also required. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In summer, it is advisable to transport in the morning and evening to avoid high temperature periods. During transportation, ensure that the container does not leak, collapse, fall, or damage. And the trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to reduce shock and generate static electricity.
    When loading and unloading, the operator should wear the corresponding protective equipment, pack it lightly and unload it lightly. It is strictly forbidden to drop and hit, so as to avoid material leakage caused by package damage.
    Overall, 2% 2C6-dinitrotoluene-3-sulfonic acid must be stored and transported in strict accordance with regulations, regardless of location, environmental control, or operating standards, to ensure the safety of personnel and the environment.