2 6 Dichloropyridine 3 Carboxamide
pyridine pyrrole pyrazine piperidine piperazine

2,6-Dichloropyridine-3-carboxamide

    Specifications

    HS Code

    424213

    Chemical Formula C6H4Cl2N2O
    Molar Mass 191.01 g/mol
    Appearance Solid (usually white to off - white)
    Melting Point 173 - 177 °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Odor Odorless or faint odor

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    General Information
    Where to Buy 2,6-Dichloropyridine-3-carboxamide in China?
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    Frequently Asked Questions

    As a leading 2,6-Dichloropyridine-3-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the use of 2,6-dichloropyridine-3-formamide?
    2% 2C6-difluoroacetophenone-3-methoxybenzoic acid is an important organic compound that is widely used in the fields of medicine, pesticides and materials.
    In the field of medicine, it can be used as a key intermediate for the synthesis of a variety of drugs. Due to its unique chemical structure, it can impart specific activities and properties to drugs. For example, in the synthesis of drugs for the treatment of some neurological diseases, it plays an indispensable role in the construction of molecular structures with precise pharmacological activity to achieve effective intervention in diseases.
    In the field of pesticides, this compound is also an important raw material for the synthesis of new pesticides. Its structural characteristics endow the pesticides synthesized on this basis with excellent biological activity, high selectivity and efficient control effect on pests, and relatively small impact on the environment, in line with the current development trend of green pesticides.
    In the field of materials, 2% 2C6-difluoroacetophenone-3-methoxybenzoic acid can participate in the preparation of functional materials. Through chemical modification and polymerization, it can be introduced into the molecular structure of the material, giving the material special optical, electrical or thermal properties, etc., to meet the special needs of different fields for material properties.
    In summary, 2% 2C6-difluoroacetophenone-3-methoxybenzoic acid plays a key role in many important fields due to its unique chemical structure and properties, providing important support for technological development and product innovation in various fields.
    What are the synthesis methods of 2,6-dichloropyridine-3-formamide?
    There are many methods for the synthesis of 2% 2C6-dinitrotoluene-3-methoxybenzoic acid, and the following are common methods.
    One is the nitrification method. First, take the appropriate toluene derivative, use the mixed acid of concentrated nitric acid and concentrated sulfuric acid as the nitrifying agent, and make it nitrate at a specific temperature and reaction time, so that the nitro group is introduced at a specific position on the benzene ring. In this process, factors such as temperature and the proportion of mixed acid are crucial. If the control is not good, it is easy to cause side reactions to cluster, which affects the purity and yield of the product. After the subsequent separation and purification steps, the intermediate containing nitro can be obtained. Then a methoxylation reagent is used to introduce a methoxy group under alkali catalysis and other conditions. Finally, through carboxylation reaction, the target product is 2% 2C6-dinitrotoluene-3-methoxybenzoic acid.
    The second is the halogenation method. First, the toluene derivative is halogenated, and a halogen atom is introduced on the benzene ring. The halogen atom can provide an active check point for the subsequent reaction. After the nitration reaction, the nitro group is introduced at a specific position. The position and number of the introduced nitro groups are affected by the structure of the reactant and the reaction conditions. Then the halogen atom is replaced by a methoxy group, and the methoxy group is formed through a nucleophilic substitution reaction. Finally, the product is synthesized by carboxylation In this path, the selectivity of the halogenation reaction and the precise control of the nitrogenation position are the key points for the successful synthesis.
    The third is the coupling method. Nitro-containing aryl halide and methoxy-containing aryl boronic acid or their derivatives are used as raw materials, and the carbon-carbon bond is constructed by means of palladium catalysis and other coupling reaction mechanisms, and the nitro-containing fragment is connected to the methoxy group. Subsequent carboxylation modification is used to obtain the target product. The coupling reaction requires fine screening and optimization of catalysts and ligands to improve the reaction activity and selectivity. At the same time, suitable reaction conditions are also required for the carboxylation step to ensure the quality of the product.
    All synthetic methods have their own advantages and disadvantages. In practical application, the choice should be made carefully according to factors such as the availability of raw materials, cost considerations, and product purity requirements.
    What are the physical and chemical properties of 2,6-dichloropyridine-3-formamide?
    2% 2C6-dinitrotoluene-3-methoxyaniline, is a kind of organic compound. Its physical and chemical properties are as follows:
    Appearance properties, usually in solid form at room temperature, or light yellow to brown crystalline powder, the specific color may vary slightly due to differences in purity.
    Melting point, about a specific temperature range, this characteristic is critical for identifying and separating the substance. The melting point data fluctuates slightly due to different precise measurement conditions.
    In terms of solubility, in most common organic solvents, such as ethanol, ether, etc., there is a certain solubility, but very little solubility in water. This characteristic determines its dispersion and reaction in different solvent systems.
    In terms of stability, the compound is relatively stable, but under certain conditions, such as high temperature, contact with strong oxidants, etc., or chemical reactions may occur, or even cause danger. In its molecular structure, functional groups such as nitro and methoxy give it unique chemical activities. Nitro has strong electron absorption, which reduces the density of the benzene ring electron cloud and affects the reactivity of the compound; methoxy is the power supply radical, which also affects the distribution of the benzene ring electron cloud. The two work together to determine its chemical properties. Because of its nitro-containing structure, it may cause combustion and explosion in case of open fire, hot topic or vibration, friction, etc., so strict safety regulations must be followed during storage and transportation to prevent accidents.
    What is the price range of 2,6-dichloropyridine-3-formamide in the market?
    2% 2C6-dihydroxypyridine-3-formaldehyde, this product is on the market, and its price range is difficult to determine. The price of the cover often changes due to many reasons, such as the quality of the quality, the amount of production, the popularity of the demand, and the difference in the situation.
    If the quality is pure and excellent, and it meets the same strict standards, the price may be high. However, if the quality is flawed, and it does not meet the fine requirements, the price should be lowered. If the production is too large and the supply exceeds the demand, the price will fall; if the production is too small and the demand is too large, the price will rise. The times are different, and there are also big differences. In case of extraordinary periods, such as the disturbance of epidemics and political changes, the price will fluctuate unpredictably.
    According to normal circumstances, this product is in the chemical raw material market. If it is of ordinary grade, buy it in batches, per kilogram or around 100 gold. If the quantity is small and you want to get it quickly, buy it from a reagent dealer, and the price may be several times higher than this. However, this is only a rough estimate, and the market conditions are ever-changing. If you want to know the exact price, you need to consult the industry in detail, and then you can get a more accurate price.
    What are the storage conditions for 2,6-dichloropyridine-3-formamide?
    2% 2C6 -diazabicyclo [3.2.0] heptyl-3-ene-7-one, this substance is an important intermediate in organic synthesis. Its storage conditions are crucial, which is related to the stability and quality of this substance.
    At normal temperature, it needs to be stored in a dry and well-ventilated place. Because moisture can easily cause chemical reactions such as hydrolysis of this substance, which affects its structure and properties, moisture protection is extremely critical. The warehouse should be kept dry, and the humidity should be controlled at a relatively low level. Generally speaking, the relative humidity should be maintained at 40% -60%.
    At the same time, light will also have an effect on it. Prolonged exposure to light may trigger photochemical reactions that can cause it to deteriorate. Therefore, when storing, avoid light, store in a dark place, or use light-shielding packaging materials for packaging.
    In terms of temperature, it is usually suitable to store in a cool environment, and the temperature should not exceed 30 ° C. Excessive temperature may accelerate the rate of decomposition or other chemical reactions. If the temperature is too low, although the reaction can be inhibited to a certain extent, in some cases, it may cause the material to crystallize or solidify, affecting the subsequent use and use effect.
    In addition, the storage place should be away from fire, heat sources and strong oxidants. Because of its certain chemical activity, in case of open flame, hot topic or contact with strong oxidant, it may cause dangerous conditions such as combustion and explosion. At the same time, it is also necessary to avoid mixing with acids, alkalis and other substances to prevent violent chemical reactions.
    During storage, it should be checked regularly to see if the packaging is in good condition and there are no signs of deterioration. Once abnormal, it should be dealt with in time to ensure the quality and safety of 2% 2C6 -diazabicyclo [3.2.0] heptyl-3-ene-7-one.