2 6 Dichloropyridine 3 Carbaldehyde
pyridine pyrrole pyrazine piperidine piperazine

2,6-Dichloropyridine-3-carbaldehyde

    Specifications

    HS Code

    944748

    Chemical Formula C6H3Cl2NO
    Molar Mass 176.00 g/mol
    Appearance Solid
    Color Off - white to light yellow
    Melting Point 88 - 92 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Purity Typically High - purity grades can be 98% or higher

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    General Information
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    Frequently Asked Questions

    As a leading 2,6-Dichloropyridine-3-carbaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-dichloropyridine-3-formaldehyde?
    2% 2C6-dinitrotoluene-3-methyl ether, this is an organic compound. Its main uses are quite extensive and its contribution to the chemical industry is significant.
    First, it can be used as a dye intermediate. In the preparation process of dyes, with its own specific chemical structure, it can participate in many reactions, and through a series of transformations, it helps to generate various dyes with bright color and excellent performance. For example, in the synthesis of some azo dyes, 2% 2C6-dinitrotoluene-3-methyl ether is used as a key intermediate to give specific chromophore groups to dye molecules, which in turn determines the color and dyeing properties of dyes.
    Second, it also plays an important role in the field of pharmaceutical synthesis. Its chemical properties enable it to be used as a starting material or intermediate to participate in the construction of drug molecules. Through ingenious chemical reactions, its structure can be modified and modified to prepare compounds with specific pharmacological activities, laying the foundation for the research and development of new drugs.
    Third, in the field of organic synthesis, it is often used as an important synthetic block. Due to the existence of nitro and methoxy groups in its structure, various reactions such as nucleophilic substitution and reduction can occur, providing the possibility for the construction of complex organic molecular structures. Organic chemists can carefully design reaction routes to achieve efficient synthesis of complex organic compounds with 2% 2C6-dinitrotoluene-3-methyl ether as the starting point according to the needs of the target molecule.
    What are the synthesis methods of 2,6-dichloropyridine-3-formaldehyde?
    The synthesis method of 2% 2C6-difluoroacetophenone-3-methyl ester is a crucial issue in the field of organic synthesis. Its synthesis routes are diverse, and each has its own advantages and disadvantages. The following are common methods.
    One is the reaction of halogenated aromatics with acylating reagents. Take halogenated aromatics, catalyze them with a specific catalyst, and place them in a suitable reaction environment with acylating reagents. This process requires precise control of the reaction temperature, time and catalyst dosage. If the temperature is too high or the time is too long, it may cause side reactions to cluster and the purity of the product will be damaged; if the temperature is too low or the time is too short, the reaction will not be completed and the yield will not be high. With this method, the basic structure of the target molecule can be effectively constructed, but the selection and preparation of halogenated aromatics may be difficult.
    The second method is to use acetophenone derivatives as starting materials. The p-acetophenone derivatives are first modified with specific functional groups, and then difluoromethyl and methyl ester groups are introduced. This process often involves multi-step reactions, such as substitution, addition, esterification, etc. The intermediates need to be properly handled during each step to prevent their decomposition or transformation. Although this approach is complicated, the requirements for reaction conditions are relatively mild, and the raw materials are easy to obtain, so it is widely used.
    The third method is to use metal-organic reagents. Metal-organic reagents have strong activity and can be coupled with fluorine-containing compounds and ester compounds. This reaction has the characteristics of high efficiency and good selectivity. However, the preparation cost of metal-organic reagents is high, and the reaction environment is strict. It must be operated under anhydrous and oxygen-free conditions, otherwise it is easy to cause the reagent to deactivate and affect the reaction process.
    The fourth is the strategy of activation through carbon-hydrogen bonds. This is an emerging synthesis method. With a specific catalyst to activate the carbon-hydrogen bond on the benzene ring, difluoromethyl and formyl groups are directly introduced. This method has high atomic economy and simple steps. However, the research and development of catalysts is still in the development stage, and there is still room for improvement in catalytic efficiency and selectivity.
    In summary, there are various synthesis methods for 2% 2C6-difluoroacetophenone-3-methyl ester, each with advantages and disadvantages. In practical applications, it is necessary to carefully select the appropriate synthesis path according to the availability of raw materials, reaction conditions, cost-effectiveness and product purity to achieve the best synthesis effect.
    What is the market price of 2,6-dichloropyridine-3-formaldehyde?
    Today there are 2,6-dihydroxypyridine-3-formaldehyde, what is the market price? This is a fine chemical product, and its price often varies depending on quality, supply and demand, and production source.
    If it is of ordinary commercial grade, with ordinary quality and abundant market supply, the price per kilogram may be in the hundreds of yuan. However, if it is of excellent quality and reaches the level of high-purity reagents, it is used in fields with strict purity requirements such as scientific research experiments, and its price should rise sharply. Or the price per gram can reach tens of yuan, which is converted to tens of thousands of yuan per kilogram.
    And if the market supply and demand imbalance, demand increases sharply and supply is limited, if a new drug is required in large quantities for research and development, its price will also rise, or far exceed the usual price. Furthermore, the origin is different, and the cost is different, which also affects its price. If it is produced in a place with advanced technology and low cost, its price may be relatively simple; if the production cost of the origin is high, its price will also rise. In short, in order to know the exact price of its market, it is necessary to consider many factors in detail, or consult chemical raw material suppliers and market brokers.
    What are the physical and chemical properties of 2,6-dichloropyridine-3-formaldehyde?
    2% 2C6-dinitrotoluene-3-ethyl formate. The physical and chemical properties of this substance are as follows:
    Its appearance is mostly light yellow to yellow needle-like crystals. The melting point is quite high, about 89-91 ° C, this characteristic keeps the substance in a solid state within a specific temperature range.
    In terms of solubility, it is slightly soluble in water, which indicates that water has limited solubility to it. However, it is easily soluble in organic solvents such as ethanol, ethyl ether, and chloroform. This difference in solubility is related to the characteristics of functional groups such as nitro and ester groups in the molecular structure. Nitro is a strong electron-absorbing group, and ester groups have certain organophilicity, which makes the compound more easily dispersed and soluble in organic solvents.
    In terms of stability, the substance is relatively stable, but it should be noted that because it contains nitro groups, it may cause combustion and explosion when heated or exposed to open flames or hot topics. In chemical reactions, its nitro groups can participate in reduction reactions and be converted into amino groups; ester groups can undergo hydrolysis reactions, generating corresponding acids and alcohols under the catalysis of acids or bases.
    In terms of toxicity, it has certain toxicity and can cause harm to human health. If it is accidentally exposed, or inhaled through the respiratory tract or absorbed by the skin, it may affect the nervous system, blood system, etc. Therefore, when operating and using, strict protective measures must be taken to ensure the safety of personnel and the environment is not polluted.
    What are the precautions for storing and transporting 2,6-dichloropyridine-3-formaldehyde?
    2% 2C6-dinitrotoluene-3-aminobenzene requires attention to many matters during storage and transportation.
    It is a dangerous chemical. When storing, the warehouse must be cool and ventilated, away from fire and heat sources, and smoke is strictly prohibited. It should be stored separately from oxidants, acids and alkalis, and should not be mixed to prevent dangerous accidents caused by violent chemical reactions. The warehouse should be equipped with suitable materials for containing leaks in order to deal with sudden leaks.
    When transporting, it should be strictly implemented in accordance with the relevant regulations on the transportation of dangerous goods. The transportation vehicle must ensure that the vehicle is in good condition, equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain and high temperature. When loading and unloading, operators should wear protective equipment, pack and unload lightly to prevent damage to packaging and containers, and avoid hazards caused by leakage of goods. The transportation route should avoid sensitive areas such as densely populated areas and water sources, and choose a safe and reasonable route. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the surrounding people, isolate the leaked contaminated area, and choose appropriate methods for treatment according to the leakage volume and actual situation. It is necessary to ensure the safety of personnel and the environment.