2 6 Dichloro 4 Difluoromethoxy Pyridine
pyridine pyrrole pyrazine piperidine piperazine

2,6-dichloro-4-(difluoromethoxy)pyridine

    Specifications

    HS Code

    221978

    Chemical Formula C6H3Cl2F2NO
    Molecular Weight 214.00
    Appearance Typically a solid
    Color Likely colorless to pale - colored
    Odor Unknown (usually has a characteristic organic chemical odor)
    Solubility In Water Low solubility (organic compound)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Vapor Pressure Low vapor pressure due to its relatively high molecular weight and non - volatile nature

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    General Information
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    Frequently Asked Questions

    As a leading 2,6-dichloro-4-(difluoromethoxy)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-dichloro-4- (difluoromethoxy) pyridine?
    2% 2C6-difluoro-4- (diethoxyformyl) pyridine, which has a wide range of uses in the chemical industry. Its main uses cover the following ends.
    The first is pharmaceutical synthesis. In the process of many drug development, it acts as a key intermediate. For example, when synthesizing a specific antibacterial drug, its unique chemical structure can participate in key reaction steps, helping to build the active molecular framework of the drug, providing the possibility for the development of new drugs with efficient antibacterial properties. In the development of some innovative drugs for specific bacterial infections, this compound plays a cornerstone role. With its special functional group, it can precisely combine with other chemicals to construct complex molecules that meet the expected pharmacological activity. < Br >
    The second is the field of materials science. In the preparation of some functional materials, 2% 2C6-difluoro-4- (diethoxyformyl) pyridine can be used as a modifier or a starting material for polymerization reactions. For example, in the process of synthesizing polymer materials with special optical or electrical properties, it can be introduced to adjust the molecular chain structure of the material, thereby changing the photoelectric properties of the material. By precisely controlling its dosage in the reaction and reaction conditions, functional materials can be customized to meet different needs, such as special materials for devices such as organic Light Emitting Diodes (OLEDs) or sensors.
    Furthermore, it also has outstanding performance in the creation of pesticides. It can be used to synthesize new insecticides or fungicides. Due to its chemical structure, which can interfere with the specific physiological processes of insects or pathogens, pesticide products with high efficiency, low toxicity and environmental friendliness can be developed. Taking the synthesis of insecticides targeting a common crop pest as an example, molecular design based on the structural properties of the compound can precisely act on the nervous system or metabolic pathways of pests to achieve effective killing of pests, while reducing the adverse effects on non-target organisms and the environment.
    What are the physical properties of 2,6-dichloro-4- (difluoromethoxy) pyridine?
    2% 2C6-difluoro-4- (diethoxymethyl) pyridine is an organic compound with the following physical properties:
    Viewed, it is often a colorless to pale yellow liquid, clear and transparent, shimmering in sunlight, like a secret treasure hidden in the world. Its smell has a slightly special aroma, but it is not rich and pungent, but seems to be hidden in the light and elegant charm, which needs to be smelled carefully.
    When talking about the boiling point, it is about a specific temperature range. At this temperature, a substance such as an emergent butterfly changes from a liquid to a gaseous state. The existence of this boiling point makes it possible to separate and purify the substance according to its characteristics by distillation. The melting point of
    is also an important property. At a certain low temperature, the material seems to enter a slumber, changing from a flowing state to a solid state, and the crystal form is regular, such as a carefully carved ice crystal, with an orderly arrangement of internal molecules. In terms of solubility, in organic solvents, such as alcohols and ethers, it can be like a duck to water and blend with it. This property is extremely critical in organic synthesis reactions. It can be used as a reaction medium or to fully mix the reactants to accelerate the process of the reaction, just like a stage builder for chemical reactions, providing a good environment for the smooth progress of the reaction.
    In terms of density, it is slightly heavier or lighter than water. Although this difference is slight, it plays a subtle and important role in many experimental operations and industrial applications. In operations such as stratification and extraction, effective separation and enrichment of substances are achieved by virtue of differences in density, just as skilled craftsmen use small differences to create exquisite utensils.
    What are the chemical properties of 2,6-dichloro-4- (difluoromethoxy) pyridine?
    2% 2C6-dioxy-4- (diethoxymethyl) pyridine is an organic compound with unique chemical properties. Let me explain in detail for you.
    First of all, in this compound, the pyridine ring gives it a certain alkalinity. The nitrogen atom on the pyridine ring has a lone pair of electrons and can accept protons. In an acidic environment, it can combine with protons to form pyridine salts.
    The structure of the dioxy, 2,6-dioxy makes the compound exhibit specific activities in certain reactions. This dioxy structure may participate in some nucleophilic substitution reactions, because the oxygen atom has a certain electronegativity, or it can make the carbon atom attached to it more vulnerable to the attack of nucleophilic reagents.
    Furthermore, the 4- (diethoxy methyl) part also affects its chemical properties. In diethoxy methyl, ethoxy is an electron-supplying group, which can produce electronic effects on the pyridine ring, affecting the distribution of electron clouds on the pyridine ring, and then affecting its reactivity. At the same time, the carbon and oxygen bonds of diethoxy methyl can be broken under certain conditions, participating in various chemical reactions, such as hydrolysis. Under suitable acidic conditions, diethoxy methyl can undergo hydrolysis to generate corresponding aldehyde compounds and ethanol.
    In addition, the compound may participate in some organic synthesis reactions, such as reacting with electrophilic reagents. Due to the influence of substituents on the electron cloud distribution of the pyridine ring, the electron cloud density at some positions of the pyridine ring changes, making it easier for electrophilic reagents to react, thereby constructing new organic compound structures, which have potential application value in the field of organic synthesis.
    What are the synthesis methods of 2,6-dichloro-4- (difluoromethoxy) pyridine?
    To prepare 2,6-difluoro-4- (diethoxyformyl) pyridine, the method is as follows:
    First, pyridine is used as the starting material. First, pyridine is used to interact with fluorinated reagents under specific conditions, and fluorine atoms are introduced to obtain fluorine-containing pyridine intermediates. In this step, attention should be paid to the reaction temperature, time and reagent ratio, so that fluorine atoms are accurately introduced into the 2,6 position. Then, the intermediate is reacted with diethoxyformylated reagents, and the diethoxyformyl group can be connected to the 4 position by means of a suitable catalyst and reaction environment. In this path, the raw material pyridine is easy to obtain, but the reaction conditions of each step are severe and need to be carefully regulated.
    Second, start with a benzene ring compound containing a specific substituent. First, a pyridine ring is constructed by cyclization reaction. During the cyclization process, the reaction is cleverly designed to introduce the required substituent into a suitable position. For example, benzene derivatives with suitable fluorine substitutions and can be converted into diethoxyformyl groups are selected, and a series of reactions such as cyclization and modification are used to achieve the synthesis of the target product. The key to this approach lies in the design and control of the cyclization reaction, and the synthesis of the initial benzene ring compound may be slightly more complicated, but it can effectively control the position and type of substituents on the pyridine ring.
    Third, a simple nitrogen-containing and carbon-containing compound can be used to gradually build a pyridine skeleton and introduce substituents through multi-step condensation and substitution reactions. For example, fluorine-containing and ethoxyformyl-related small molecules are used as raw materials and gradually spliced through multi-step reactions to finally synthesize the target pyridine product. Although this method is cumbersome in steps, it is flexible and can fine-tune the reaction conditions and raw materials according to actual needs to optimize the yield and selectivity.
    Each synthesis method has its own advantages and disadvantages. In practical application, when considering many factors such as raw material availability, cost, yield and product purity, the optimal method is selected.
    What is the price range of 2,6-dichloro-4- (difluoromethoxy) pyridine in the market?
    The price range of "2,6-difluoro-4- (diethoxymethyl) pyridine" you asked about in the market is not a single word. The price is determined by various factors, making it difficult to determine.
    First, the price of raw materials is related to its cost. If the price of various raw materials required for the preparation of this compound fluctuates due to changes in weather, geographical location, and supply and demand, the price of the product will also fluctuate. If the raw materials are abundant and oversupplied, the price may decline; conversely, if the raw materials are scarce and the supply does not continue, the price will rise.
    Second, the difficulty of the preparation process is also the key. If the preparation of this pyridine derivative is complicated, requires exquisite equipment, superb skills, and consumes a lot of manpower and material resources, the cost is high, and the price is not cheap. On the contrary, if the process is simple, the cost may be reduced, and the price is expected to drop.
    Third, the market supply and demand situation has a great impact. If the compound is in strong demand in the fields of medicine and chemical industry, but the supply is limited, the price will increase; if the demand is weak and the supply is excessive, the price will decline.
    Fourth, the size and brand of the manufacturer also have an impact. Large factories may have slightly lower costs due to scale effects; and well-known brands may be able to price slightly higher due to their quality reputation.
    In summary, it is difficult to determine the price range of "2,6-difluoro-4- (diethoxymethyl) pyridine" in the market, which may vary from time to time and from place to place. For details, please consult the chemical product trading platform, supplier or industry insiders to obtain a more accurate price.