2 6 Dichloro 3 Trifluoromethylpyridine
pyridine pyrrole pyrazine piperidine piperazine

2,6-Dichloro-3-trifluoromethylpyridine

    Specifications

    HS Code

    149551

    Chemical Formula C6H2Cl2F3N
    Molecular Weight 215.99
    Appearance colorless to light yellow liquid
    Boiling Point 198 - 200 °C
    Melting Point N/A
    Density 1.53 g/cm³
    Vapor Pressure N/A
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents
    Flash Point 84 °C
    Purity Typically high - purity products available (e.g., 98%+)

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    General Information
    Where to Buy 2,6-Dichloro-3-trifluoromethylpyridine in China?
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    Frequently Asked Questions

    As a leading 2,6-Dichloro-3-trifluoromethylpyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,6-dichloro-3-trifluoromethylpyridine?
    2% 2C6 -dioxo-3 -trifluoromethylpyridine, which is an important intermediate in organic synthesis. In the field of medicine, it is often a key starting material for the creation of new drugs. For example, when developing some antiviral and anti-tumor drugs, with their unique chemical structure, they can build a molecular skeleton with specific biological activities, laying the foundation for the birth of new drugs.
    In the field of pesticides, its use is also quite extensive. It can be used as a core component in the synthesis of high-efficiency and low-toxicity pesticides, such as some new insecticides and fungicides. Due to its structural characteristics, it can endow pesticides with excellent biological activity and environmental adaptability, protecting crops from pests and diseases while reducing the negative impact on the environment.
    In addition, in the field of materials science, it also has its own role. It can participate in the synthesis of functional materials, such as materials with special optical and electrical properties. Through chemical modification and polymerization, it is integrated into the material structure, thus giving the material unique properties and meeting the specific needs of electronics, optics and other fields.
    From the above, 2% 2C6-dioxo-3-trifluoromethylpyridine plays an indispensable role in many fields and is of great significance to promote the development of related industries.
    What are the synthesis methods of 2,6-dichloro-3-trifluoromethylpyridine?
    To prepare 2,6-difluoro-3-trifluoromethylpyridine, there are many methods, and the main ones are selected, and there are the following numbers.
    One is the halogen exchange method. This starts with chloropyridine derivatives, which react with fluoride under specific conditions, and chlorine is replaced by fluorine to form the target product. In this process, the catalyst and reaction conditions need to be carefully selected to promote the reaction to occur efficiently and with high selectivity. If a chloropyridine is used as the raw material, an appropriate amount of potassium fluoride is added to a specific organic solvent, and a specific phase transfer catalyst is added to control the temperature, pressure and reaction, the product can be obtained. However, in this way, the selection of raw materials is limited, and the halogen exchange efficiency and selectivity need to be carefully regulated.
    The second is the method of building a pyridine ring. First, the pyridine ring is constructed with appropriate raw materials, and fluorine and trifluoromethyl are introduced at the same time. For example, small molecules containing fluorine and trifluoromethyl are used as starting materials, and the pyridine ring is constructed through a series of reactions such as condensation and cyclization. The availability of starting materials for this method may be the key, and the reaction steps may be complicated. The reaction sequence and conditions need to be carefully planned to ensure the yield and selectivity of each step and ensure the feasibility of the overall synthesis route.
    The third is the direct fluorination method. For the direct fluorination of existing pyridine derivatives, fluorine atoms and trifluoromethyl are introduced. This requires specific fluorination reagents and reaction conditions to precisely control the position and degree of fluorination. For example, new fluorination reagents are selected to fluorinate specific pyridine substrates under mild conditions. However, the direct fluorination reaction activity and selectivity are difficult to control, and side reactions are prone to occur, so the reaction conditions and fluorination reagents are strictly required.
    Synthesis of 2,6-difluoro-3-trifluoromethylpyridine has advantages and disadvantages. Practical application requires comprehensive consideration of factors such as raw material availability, cost, yield and selectivity, and the optimal route is selected to achieve the purpose of efficient and economical synthesis.
    What are the physical properties of 2,6-dichloro-3-trifluoromethylpyridine?
    2% 2C6-difluoro-3-trifluoromethylpyridine, this is a special organic compound. Its physical properties are unique and it is widely used in many fields such as chemical industry, medicine, pesticides, etc.
    Looking at its properties, it is mostly colorless to light yellow liquid under normal conditions, with a pure and uniform texture and no impurities visible. The smell is unique, but it is not pungent and unpleasant, and it has a certain volatility. It gradually emits in the air.
    Boiling point and melting point are also important physical properties. Its boiling point is moderate. Due to the presence of fluorine atoms in the molecular structure, fluorine atoms have high electronegativity and cause different intermolecular forces. The boiling point is different from that of ordinary pyridine compounds. This property makes it particularly critical for temperature control during separation, purification and reaction. The melting point determines its physical state under specific temperature conditions, and it can be solid at low temperatures, making it easy to store and transport.
    In terms of solubility, the compound has good solubility in organic solvents such as ethanol, ether and acetone. Due to the molecular structure of the organic solvent and 2% 2C6-difluoro-3-trifluoromethyl pyridine molecules, suitable interaction forces, such as van der Waals force, hydrogen bond, etc., can be formed between them. However, the solubility in water is poor, because its molecular polarity does not match the polarity of water, and the fluoroalkyl chain is hydrophobic.
    Density is also a factor to consider its physical properties. Due to the relatively large atomic mass of fluorine atoms in the molecule, the density is slightly higher than that of common hydrocarbons. This density characteristic has a significant impact on operations such as liquid-liquid separation and mixing.
    In addition, the vapor pressure of 2% 2C6-difluoro-3-trifluoromethylpyridine has a specific value at a specific temperature. The vapor pressure reflects the difficulty of volatilization, and puts forward corresponding requirements for ventilation conditions in the production and storage environment to ensure safe operation and avoid danger caused by vapor accumulation.
    What is the market price of 2,6-dichloro-3-trifluoromethylpyridine?
    Today there are 2,6-difluoro-3-trifluoromethylpyridine, what is the price in the market? I try to find out for you. However, the price in the market often varies according to time, place, quality and quantity, and it is difficult to have a fixed number.
    This product, or used in medicine, pesticides, materials and other fields, has different needs and different prices. In the market of chemical raw materials, if its quality is high and the mass production is sufficient, the price may be relatively easy; if its preparation is difficult, the output is scarce, or the market is in urgent need, the price will rise.
    In the past, the price of such fine chemicals fluctuated. Or due to the abundance of raw materials, the change of process, and the guidance of policies, the price fluctuates. If you want to know the current price, you should consult chemical raw material suppliers, traders, or visit relevant trading platforms. They are in the market, familiar with the current price, and can get the exact number.
    If you want to know the market price of 2,6-difluoro-3-trifluoromethylpyridine, you need to study the market carefully and consult many parties to obtain its approximation. It is difficult to determine it suddenly.
    What are the storage conditions for 2,6-dichloro-3-trifluoromethylpyridine?
    2% 2C6-dideuterium-3-trifluoromethylpyridine, this substance is extraordinary, and its storage conditions are quite critical.
    According to the method of "Tiangong Kaiwu", the storage of this substance should be placed in a cool and dry place. Those who are cool can be protected from the intense sun. The sun is hot, or it may cause unpredictable changes, which will damage its quality. Drying is also essential. Moisture can easily lead to deliquescence, or biochemical reactions, which will damage its original state.
    And it needs to be kept away from fire and heat sources. Fire can cause the temperature to rise sharply. If this object encounters high temperature, it may burn or explode, and it is dangerous. The same is true for heat sources. Even if the temperature does not reach the ignition point, long-term heating will cause its components to decompose and deteriorate.
    Furthermore, it should be stored separately from oxidants, acids and other substances. Oxidants are strongly oxidizing, and acids are corrosive. The two meet with 2% 2C6-dideuterium-3-trifluoromethylpyridine, or cause a violent reaction, endangering safety.
    Storage places should also be equipped with suitable materials to deal with possible leaks. If there is a leak, it can be disposed of in time to prevent it from spreading and causing greater harm. In this way, it is a way to properly store 2% 2C6-dideuterium-3-trifluoromethylpyridine.